Noninvasive evaluation of antiangiogenic effect in a mouse tumor model by DCE-MRI with Gd-DTPA cystamine copolymers.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Molecular Pharmaceutics

• Publication date

  2010-02-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/mp900153fPMID 19958031PMCID PMC2815092
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural effect on degradability and in vivo contrast enhancement of polydisulfide Gd(III) complexes as biodegradable macromolecular MRI contrast agents.

  2009cited by this paper
• Application of a biodegradable macromolecular contrast agent in dynamic contrast‐enhanced MRI for assessing the efficacy of indocyanine green‐enhanced photothermal cancer therapy

  2009cited by this paper
• Characterization of tumor angiogenesis with dynamic contrast‐enhanced MRI and biodegradable macromolecular contrast agents in mice

  2008cited by this paper
• Bevacizumab, a humanized anti‐angiogenic monoclonal antibody for the treatment of colorectal cancer

  2007cited by this paper
• VEGF-targeted cancer therapy strategies: current progress, hurdles and future prospects.

  2007cited by this paper
• Modification of Gd‐DTPA cystine copolymers with PEG‐1000 optimizes pharmacokinetics and tissue retention for magnetic resonance angiography

  2007cited by this paper
• Diffusion-weighted and macromolecular contrast enhanced MRI of tumor response to antivascular therapy with ZD6126

  2007cited by this paper
• Signal transduction of VEGF receptors toward angiogenesis

  2006cited by this paper
• Gd-DTPA l-Cystine Bisamide Copolymers as Novel Biodegradable Macromolecular Contrast Agents for MR Blood Pool Imaging

  2006cited by this paper
• Effect of size and charge on pharmacokinetics and in vivo MRI contrast enhancement of biodegradable polydisulfide Gd(III) complexes.

  2006cited by this paper
• Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents

  2006cited by this paper
• Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies.

  2006cited by this paper
• Mineralocorticoid receptor mediates glucocorticoid treatment effects in the autoimmune mouse ear.

  2006cited by this paper
• Pharmacokinetics, Biodistribution and Contrast Enhanced MR Blood Pool Imaging of Gd-DTPA Cystine Copolymers and Gd-DTPA Cystine Diethyl Ester Copolymers in a Rat Model

  2006cited by this paper
• Bevacizumab--current status and future directions.

  2005cited by this paper
• Early Antiangiogenic Activity of SU11248 Evaluated In vivo by Dynamic Contrast-Enhanced Magnetic Resonance Imaging in an Experimental Model of Colon Carcinoma

  2005cited by this paper
• Pharmacokinetics and Tissue Retention of (Gd-DTPA)-Cystamine Copolymers, a Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agent

  2005cited by this paper
• Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging.

  2005cited by this paper
• Dynamic contrast-enhanced MR imaging kinetic parameters and molecular weight of dendritic contrast agents in tumor angiogenesis in mice.

  2005cited by this paper
• Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478.

  2005cited by this paper
• Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy.

  2005cited by this paper
• Contrast‐enhanced MRI with new biodegradable macromolecular Gd(III) complexes in tumor‐bearing mice

  2005cited by this paper
• Dynamic contrast enhanced MRI in the differential diagnosis of soft tissue tumors.

  2005cited by this paper
• Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

  2004cited by this paper
• New model for analysis of dynamic contrast‐enhanced MRI data distinguishes metastatic from nonmetastatic transplanted rodent prostate tumors

  2004cited by this paper
• Extracellular biodegradable macromolecular gadolinium(III) complexes for MRI

  2004cited by this paper
• Vascular endothelial growth factor: basic science and clinical progress.

  2004cited by this paper
• Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470.

  2003cited by this paper
• Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis.

  2003cited by this paper
• Angiogenesis modulation in cancer research: novel clinical approaches

  2002cited by this paper
• VEGF and the quest for tumour angiogenesis factors

  2002cited by this paper
• Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

  2000cited by this paper
• Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor.

  2000cited by this paper
• Vascular-specific growth factors and blood vessel formation

  2000cited by this paper
• Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: comparison of macromolecular and small-molecular contrast media.

  1998cited by this paper
• Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders.

  1997cited by this paper
• Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody.

  1996cited by this paper
• [Regulators of angiogenesis].

  1996cited by this paper
• Measurement of capillary permeability to macromolecules by dynamic magnetic resonance imaging: A quantitative noninvasive technique

  1993cited by this paper
• Regulators of angiogenesis.

  1991cited by this paper
• Albumin labeled with Gd-DTPA as an intravascular, blood pool-enhancing agent for MR imaging: biodistribution and imaging studies.

  1987cited by this paper

• Effect of Methylene Blue and PI3K-Akt Pathway Inhibitors on the Neurovascular System after Chronic Cerebral Hypoperfusion in Rats

  2020influential citation
• Gd-encapsulated carbonaceous dots for accurate characterization of tumor vessel permeability in magnetic resonance imaging.

  2019cites this paper
• Real-time monitoring of tumor vascular disruption induced by radiofrequency assisted gadofullerene

  2018cites this paper
• Molecular imaging of the tumor microenvironment☆

  2017cites this paper
• Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1α with Targeted Multifunctional ECO/siRNA Nanoparticles.

  2016cites this paper
• Metal-containing and related polymers for biomedical applications.

  2016cites this paper
• Trastuzumab improves tumor perfusion and vascular delivery of cytotoxic therapy in a murine model of HER2+ breast cancer: preliminary results

  2016cites this paper
• EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma

  2015cites this paper
• Anti-angiogenic Effects of Bumetanide Revealed by DCE-MRI with a Biodegradable Macromolecular Contrast Agent in a Colon Cancer Model

  2015cites this paper
• Evaluation of multimodality imaging using image fusion with MRI and CEUS in an experimental animal model

  2015cites this paper
• Diffusion-weighted magnetic resonance imaging for early response assessment of chemoradiotherapy in patients with nasopharyngeal carcinoma.

  2014cites this paper
• Non-invasive quantification of anti-angiogenic therapy by contrast-enhanced MRI in experimental pancreatic cancer

  2014cites this paper
• Early detection of antiangiogenic treatment responses in a mouse xenograft tumor model using quantitative perfusion MRI

  2014cites this paper
• Evaluation of multimodality imaging using image fusion with ultrasound tissue elasticity imaging in an experimental animal model

  2014cites this paper
• Feasibility of Small Animal Anatomical and Functional Imaging with Neutrons: A Monte Carlo Simulation Study

  2014cites this paper
• Stratification of 18F-Labeled PET Imaging Agents for the Assessment of Antiangiogenic Therapy Responses in Tumors

  2013cites this paper
• Polymeric Materials for Theranostic Applications

  2013cites this paper
• Low‐molecular contrast agent dynamic contrast‐enhanced (DCE)‐MRI and diffusion‐weighted (DW)‐MRI in early assessment of bevacizumab treatment in breast cancer xenografts

  2013cites this paper
• A dedicated automated injection system for dynamic contrast‐enhanced MRI experiments in mice

  2013cites this paper
• Polydisulfide manganese(II) complexes as non‐gadolinium biodegradable macromolecular MRI contrast agents

  2012cites this paper
• Integrin αvβ3–Targeted Dynamic Contrast–Enhanced Magnetic Resonance Imaging Using a Gadolinium-Loaded Polyethylene Gycol–Dendrimer–Cyclic RGD Conjugate to Evaluate Tumor Angiogenesis and to Assess Early Antiangiogenic Treatment Response in a Mouse Xenograft Tumor Model

  2012cites this paper
• Imaging in the age of molecular medicine: monitoring of anti-angiogenic treatments.

  2012cites this paper
• Tracing and quantification of pharmaceuticals using MR imaging and spectroscopy at clinical MRI system

  2012cites this paper
• Assessment of neovascular permeability in a pancreatic tumor model using dynamic contrast-enhanced (DCE) MRI with contrast agents of different molecular weights

  2011cites this paper
• Polydisulfide Based Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agents.

  2010cites this paper
• Assessment of the In vivo Antitumor Effects of ENMD-2076, a Novel Multitargeted Kinase Inhibitor, against Primary and Cell Line–Derived Human Colorectal Cancer Xenograft Models

  2010cites this paper
• Stability and Biodistribution of a Biodegradable Macromolecular MRI Contrast Agent Gd-DTPA Cystamine Copolymers (GDCC) in Rats

  2010cites this paper
• Nanotheranostics and image-guided drug delivery: current concepts and future directions.

  2010cites this paper
• Current Awareness in NMR in Biomedicine

  2010cites this paper