Reimplementation of the Potjans-Diesmann cortical microcircuit model: from NEST to Brian

This work targets the replicability of computational models to provide the community with tested and proven open-source models to be used in new studies and implementations. The Potjans-Diesmann model describes a cortical microcircuit containing two cell types (excitatory and inhibitory) distributed in four layers, and represents the cortical network below a surface of 1 mm2. The original implementation of the Potjans-Diesmann model was based on the NEST simulator and our goal here was to re-implement the model in the Brian 2 simulator and obtain the same results presented in the reference article. We did not replicate analyses that involve changes in the network structure. Our replicated network model presents activity dynamic patterns very similar to the ones observed in the original model, with comparisons made in terms of firing rates and synchrony and irregularity measures. In conclusion, the Potjans-Diesmann model was successfully replicated in a different platform than the one in which it was originally implemented.

• Publication year

  2018

• Venue

  bioRxiv

• Publication date

  2018-01-16

• Fields of study

  Biology, Computer Science

• Identifiers
  DOI 10.1101/248401
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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