Inhibition of microtubule polymerization by synthetic estrogens: formation of a ribbon structure.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Journal of Biochemistry (Tokyo)

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/OXFORDJOURNALS.JBCHEM.A121988PMID 3654591
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Diethylstilbestrol induces metaphase arrest and inhibits microtubule assembly.

  1985cited by this paper
• Diethylstilboestrol: the binding and effects of diethylstilboestrol upon the polymerisation and depolymerisation of purified microtubule protein in vitro.

  1985cited by this paper
• Disruptive effect of diethylstilbestrol on microtubules.

  1984cited by this paper
• Relative carcinogenic activity of various synthetic and natural estrogens in the Syrian hamster kidney.

  1983cited by this paper
• Bundling of microtubules in vitro by fodrin.

  1983cited by this paper
• Morphologic and neoplastic transformation of Syrian hamster embryo fibroblasts by diethylstilbestrol and its analogs.

  1982cited by this paper
• Complete amino acid sequence of alpha-tubulin from porcine brain.

  1981cited by this paper
• Conformational analysis of nonsteroidal estrogens: The effect of conformer populations on the binding affinity of meso- and dl-hexestrol to the estrogen receptor.

  1981cited by this paper
• Complete amino acid sequence of beta-tubulin from porcine brain.

  1981cited by this paper
• Different tubulin polymers are produced by microtubule-associated proteins MAP2 and tau in the presence of guanosine 5'-(alpha, beta-methylene)triphosphate.

  1980cited by this paper
• The interactions between calcium-dependent regulator protein of cyclic nucleotide phosphodiesterase and microtubule proteins. II. Association of calcium-dependent regulator protein with tubulin dimer.

  1979cited by this paper
• Polymerization of tubulin in the presence of colchicine or podophyllotoxin. Formation of a ribbon structure induced by guanylyl-5'-methylene diphosphonate.

  1979cited by this paper
• Microtubule assembly in vitro. Purification of assembly-promoting factors.

  1977cited by this paper
• Polymorphism of tubulin assembly. In vitro formation of sheet, twisted ribbon and microtubule.

  1976cited by this paper
• Quantitative electron microscopy of microtubule assembly in vitro.

  1975cited by this paper
• Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules.

  1974cited by this paper
• Microtubule assembly in the absence of added nucleotides.

  1973cited by this paper
• Biochemical studies of diethylstilbestrol-induced kidney tumors in the golden Syrian hamster.

  1971cited by this paper
• Peroxidase-catalyzed oxidation of diethylstilbestrol.

  1962cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper
• The hexahydro derivatives of meso-hexestrol.

  1948cited by this paper

• Estrogens—Origin of Centrosome Defects in Human Cancer?

  2022cites this paper
• Regioselective and Stereoselective Heck-Matsuda Arylations of Trisubstituted Allylic Alkenols and Their Silyl and Methyl Ether Derivatives To Access Two Contiguous Stereogenic Centers: Expanding the Redox-Relay Process and Application in the Total Synthesis of meso-Hexestrol.

  2018cites this paper
• Identification of Proteomic Signatures of Exposure to Marine Pollutants in Mussels (Mytilus edulis)*S

  2006cites this paper
• Tetrahydrofuran-mediated radical processes: stereoselective synthesis of d,l-hexestrol

  2003cites this paper
• Cytotoxicity of synthetic estrogen and related compounds in various tumor-derived cells.

  2001cites this paper
• 2-Methoxymethylestradiol: a new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics.

  2001cites this paper
• Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats.

  2001cites this paper
• Cytoskeleton-interacting activity of geiparvarin, diethylstilbestrol and conjugates.

  2001cites this paper
• Diethylstilbestrol (DES)-induced cell cycle delay and meiotic spindle disruption in mouse oocytes during in-vitro maturation.

  2000cites this paper
• Geiparvarin and derivatives in combination with taxol: effect on microtubular organization in 3T3 fibroblasts.

  1997cites this paper
• Interaction of geiparvarin and related compounds with purified microtubular protein.

  1996cites this paper
• Estrogen receptor-mediated transcriptional activation by 17 beta-estradiol and its analogs.

  1996cites this paper
• Hormonal Carcinogenesis II

  1996cites this paper
• Induction of Micronucleation, Spindle Disturbances, and Mitotic Arrest in Human Chorionic Villi Cells by 17ß-Estradiol, Diethylstilbestrol, and Coumestrol

  1996cites this paper
• Hormones and the cytoskeleton of animals and plants.

  1996cites this paper
• [Biosynthesis and microbial transformation of griseofulvin and carcinogenesis and prevention of cancer by estrogens].

  1995cites this paper
• Natural estrogens induce modulation of microtubules in Chinese hamster V79 cells in culture.

  1995cites this paper
• Effects of some diethylstilbestrol metabolites and analogs on cytotoxicity and aneuploidy induction in Chinese hamster V79 cells.

  1995cites this paper
• Relationship between cytotoxic and microtubule disruptive activities of (+)-, (-)- and (+/-)-indenestrol A and B monomethyl ethers in Chinese hamster V79 cells in culture.

  1995cites this paper
• Glucocorticoid receptor inhibits microtubule assembly in vitro.

  1995cites this paper
• Microtubule disruption induced by estradiol in estrogen receptor-positive and -negative human breast cancer cell lines.

  1994cites this paper
• Inhibition of DNA topoisomerase I activity by diethylstilbestrol and its analogues.

  1993cites this paper
• Effects of (+)-, (-)- and (+/-)-indenestrols A and B on microtubule distribution and cytotoxicity in Chinese hamster V79 cells.

  1993cites this paper
• Interaction of the Tumor Inhibitor IKP‐104, a 4(1H)‐Pyridinone Derivative, with Microtubule Proteins

  1992cites this paper
• Effect of estradiol and ethynylestradiol on microtubule distribution in Chinese hamster V79 cells.

  1992cites this paper
• Effects of 3,3'-dihydroxy-alpha,beta-diethylstilbene and 3,3',4,5'-tetrahydroxystilbene on microtubule assembly in vitro, aneuploidy induction, and cellular microtubule and actin networks.

  1992cites this paper
• Effects of (+)-, (-)- and (+/-)-indenestrols A and B on microtubule polymerization.

  1992cites this paper
• Inhibition of transcription by mammalian ribonucleic acid polymerase II: effects of diethylstilbestrol and its analogues.

  1991cites this paper
• Qualitative study of the interaction mechanism of estrogenic drugs with tubulin.

  1991cites this paper
• Effects of diethylstilbestrol and its methyl ethers on aneuploidy induction and microtubule distribution in Chinese hamster V79 cells.

  1991cites this paper
• Effects of antimitotic agents on tubulin-nucleotide interactions.

  1991cites this paper
• Evidence of intercalation of trans-diethylstilbestrol and its methyl ether derivatives in multibilayers of egg phosphatidylcholine by high-power deuterium nuclear magnetic resonance (2H-NMR) spectroscopy.

  1990cites this paper
• Effect of meso-hexestrol, a synthetic estrogen, on S-tubulin.

  1990cites this paper
• Diethylcarbamazine, antifilarial drug, inhibits microtubule polymerization and disrupts preformed microtubules.

  1990cites this paper
• Effects of synthetic estrogens, (R,R)-(+)-, (S,S)-(-)-, dl- and meso-hexestrol stereoisomers on microtubule assembly.

  1990cites this paper
• Diethylcarbamazine, antifilarial drug, inhibits microtubule polymerization and disrupts preformed microtubules.

  1990cites this paper
• and steroid hormone secretion: a review

  1989cites this paper
• Biotransformation, estrogenicity, and steroid structure as determinants of dysmorphogenic and generalized embryotoxic effects of steroidal and nonsteroidal estrogens.

  1989cites this paper
• Estramustine inhibits monocyte phagocytosis

  1988cites this paper
• Carbon-13 nuclear magnetic resonance study of meso-hexestrol and its derivatives.

  1988cites this paper
• Studies of the interaction of chemicals with microtubule assembly in vitro can be used as an assay for detection of cytotoxic chemicals and possible inducers of aneuploidy.

  1988cites this paper
• 13C NMR spectra of para‐substituted methoxybenzenes and phenols in the solid state: Examination of chemical shift non‐equivalence in ortho and meta carbons related to non‐equivalent electron distribution, and application to assignment of peaks in meso‐hexestrol and its derivatives

  1988cites this paper
• Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.

  1988cites this paper