STABILISING HEMOCYANINS: STEPS TOWARDS FORMULATION OF NEW PROTEIN PHARMACEUTICALS

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  2016-02-29

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Thermal denaturation and protein stability analysis of Haliotis rubra hemocyanin

  2016cited by this paper
• Protein Production and Purification

  2015cited by this paper
• Formulation of abalone hemocyanin with high antiviral activity and stability.

  2014cited by this paper
• The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.

  2013cited by this paper
• Antiviral agents for herpes simplex virus.

  2013cited by this paper
• Thermal stability of lysozyme as a function of ion concentration: A reappraisal of the relationship between the Hofmeister series and protein stability

  2013cited by this paper
• Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism.

  2013cited by this paper
• Immunogenicity of protein aggregates--concerns and realities.

  2012cited by this paper
• Protein aggregation: kinetics versus thermodynamics.

  2012cited by this paper
• Intracutaneous and intravesical immunotherapy with keyhole limpet hemocyanin compared with intravesical mitomycin in patients with non-muscle-invasive bladder cancer: results from a prospective randomized phase III trial.

  2012cited by this paper
• Stabilizing effect of saccharides on bovine plasma protein: a calorimetric study.

  2012influential reference
• Enhancement of the Activity of a Lactobacilli-Aggregating Peptide by Freezing Treatment

  2012cited by this paper
• Unexpected effects of macromolecular crowding on protein stability.

  2012cited by this paper
• Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non‐specific immunostimulatory effects

  2012cited by this paper
• Ion specific influences on the stability and unfolding transitions of a naturally aggregating protein; RecA.

  2012cited by this paper
• Analytical methods and formulation factors to enhance protein stability in solution

  2012cited by this paper
• In vitro antiviral activity against herpes simplex virus in the abalone Haliotis laevigata.

  2011cited by this paper
• The use of dynamic light scattering and brownian microscopy to characterize protein aggregation.

  2011cited by this paper
• Principles and Techniques of Biochemistry and Molecular Biology

  2010cited by this paper
• Correlating aggregation kinetics and stationary diffusion in protein-sodium salt systems observed with dynamic light scattering.

  2010cited by this paper
• Molluscan mega-hemocyanin: an ancient oxygen carrier tuned by a ~550 kDa polypeptide

  2010cited by this paper
• Microcalorimetry of proteins and their complexes.

  2009cited by this paper
• Keyhole limpet hemocyanin: 9-A CryoEM structure and molecular model of the KLH1 didecamer reveal the interfaces and intricate topology of the 160 functional units.

  2009cited by this paper
• Molecular crowding and solvation: direct and indirect impact on protein reactions.

  2009cited by this paper
• Defining the stability of multimeric proteins.

  2009cited by this paper
• An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection.

  2008influential reference
• Thermal stability of homologous functional units of Helix pomatia hemocyanin does not correlate with carbohydrate content

  2008cited by this paper
• Calorimetry and Thermodynamics in Drug Design

  2008cited by this paper
• Anti-Herpes Effect of Hemocyanin Derived from the Mollusk Rapana thomasiana

  2008influential reference
• Irreversible Thermal Denaturation of β-Hemocyanin of Helix pomatia and its Substructures Studied by Differential Scanning Calorimetry

  2007cited by this paper
• Handbook of proteins : structure, function and methods

  2007cited by this paper
• Respiratory protein–generated reactive oxygen species as an antimicrobial strategy

  2007cited by this paper
• Nautilus pompilius hemocyanin: 9 A cryo-EM structure and molecular model reveal the subunit pathway and the interfaces between the 70 functional units.

  2007cited by this paper
• Minireview: Recent progress in hemocyanin research.

  2007influential reference
• Monitoring protein aggregation during thermal unfolding in circular dichroism experiments

  2006cited by this paper
• Polysaccharides for drug delivery and pharmaceutical applications

  2006cited by this paper
• Differential scanning calorimetry of the irreversible denaturation of Rapana thomasiana (marine snail, Gastropod) hemocyanin.

  2005influential reference
• Glycans in cancer and inflammation — potential for therapeutics and diagnostics

  2005cited by this paper
• Structure and stability of arthropodan hemocyanin Limulus polyphemus.

  2005cited by this paper
• The prophenoloxidase‐activating system in invertebrates

  2004cited by this paper
• Characterization of keyhole limpet hemocyanin (KLH) glycans sharing a carbohydrate epitope with Schistosoma mansoni glycoconjugates.

  2004cited by this paper
• Antiviral properties of hemocyanin isolated from shrimp Penaeus monodon.

  2004influential reference
• Protein structure, stability and solubility in water and other solvents.

  2004cited by this paper
• Effect of pegylation on pharmaceuticals

  2003cited by this paper
• Strategies in the design of antiviral drugs

  2002cited by this paper
• Introduction to protein architecture : the structural biologyof proteins

  2001cited by this paper
• Hemocyanins and Invertebrate Evolution*

  2001cited by this paper
• Thermodynamics and kinetics for the biological sciences

  2001cited by this paper
• Immunogenicity of a fucosyl-GM1-keyhole limpet hemocyanin conjugate vaccine in patients with small cell lung cancer.

  1999cited by this paper
• Organization of the <400 kDa subunit, and amino acid sequence of its functional units f, g and h

  1999influential reference
• Circular dichroism study of the hemocyanin thermostability

  1998influential reference
• Therapeutic protein and peptide formulation and delivery

  1997cited by this paper
• A brief history of hemoglobins: plant, animal, protist, and bacteria.

  1996cited by this paper
• How Hofmeister ion interactions affect protein stability.

  1996cited by this paper
• Extreme thermostability of tarantula hemocyanin

  1995cited by this paper
• GM2-KLH conjugate vaccine: increased immunogenicity in melanoma patients after administration with immunological adjuvant QS-21.

  1995cited by this paper
• Protein Stability and Folding: Theory and Practice

  1995cited by this paper
• COMPARATIVE STUDY OF HEMOCYANINS OF DECAPODA USING ISOELECTRIC FOCUSING

  1995cited by this paper
• Common Oxygen Binding Site in Hemocyanins from Arthropods and Mollusks. Evidence from Raman Spectroscopy and Normal Coordinate Analysis

  1994cited by this paper
• PARTICLE SIZING BY PHOTON-CORRELATION SPECTROSCOPY .4. RESOLUTION OF BIMODALS AND COMPARISON WITH OTHER PARTICLE SIZING METHODS.

  1993cited by this paper
• The control of protein stability and association by weak interactions with water: how do solvents affect these processes?

  1993cited by this paper
• Chemical and physical pathways of protein degradation

  1992cited by this paper
• Theoretical analysis of Lumry-Eyring models in differential scanning calorimetry.

  1992cited by this paper
• Differential scanning calorimetry of lobster haemocyanin.

  1990influential reference
• A simple model for proteins with interacting domains. Applications to scanning calorimetry data.

  1989cited by this paper
• Differential scanning calorimetry of the irreversible thermal denaturation of thermolysin.

  1988influential reference
• Protein stability curves

  1987cited by this paper
• EVOLUTION AND FUNCTION OF STRUCTURALLY DIVERSE SUBUNITS IN THE RESPIRATORY PROTEIN HEMOCYANIN FROM ARTHROPODS

  1986cited by this paper
• Proteins. Structures and molecular properties, T.E. Creighton. W. H. Freeman and Company, New York (1984), 515, $36.95

  1985cited by this paper
• Annual review of biophysics and biophysical chemistry

  1985cited by this paper
• Hemocyanin--a current perspective.

  1983cited by this paper
• Stabilization of protein structure by sugars.

  1982cited by this paper
• The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins.

  1982cited by this paper
• Increased thermal stability of proteins in the presence of sugars and polyols.

  1979influential reference
• Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol.

  1977cited by this paper
• A thermodynamic approach to the problem of stabilization of globular protein structure: a calorimetric study.

  1974cited by this paper
• Principles that govern the folding of protein chains.

  1973cited by this paper
• Some factors in the interpretation of protein denaturation.

  1959cited by this paper
• Conformation Changes of Proteins

  1954cited by this paper
• Free Volume and Entropy in Condensed Systems III. Entropy in Binary Liquid Mixtures; Partial Molal Entropy in Dilute Solutions; Structure and Thermodynamics in Aqueous Electrolytes

  1945cited by this paper
• The Activated Complex in Chemical Reactions

  1935cited by this paper
• THE HAEMOCYANIN OF LIMULUS POLYPHEMUS

  1910cited by this paper

• No citing papers are available for this paper.