EXPLORING ANTI-HYPERGLYCEMIC POTENTIAL OF ALKALOID COMPOUNDS FROM CATHARANTHUS ROSEUS G. DON (L) AGAINST VARIOUS TYPE II DIABETES TARGETS BY IN SILICO VIRTUAL SCREENING

No abstract is available for this paper.

• Publication year

  2017

• Venue

  World journal of Pharmacy and pharmaceutical sciences

• Publication date

  2017-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.20959/WJPPS20178-9647
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

  2017cited by this paper
• NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis

  2016cited by this paper
• Predicting drug metabolism: experiment and/or computation?

  2015cited by this paper
• Compounds from rosemary and Mexican oregano are natural inhibitors of dipeptidyl peptidase‐IV, a target for type‐2 diabetes management (1045.20)

  2014cited by this paper
• The role of drug metabolizing enzymes in clearance

  2014cited by this paper
• Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase

  2014cited by this paper
• A novel 11β-HSD1 inhibitor improves diabesity and osteoblast differentiation.

  2014cited by this paper
• Dictionary of natural products

  2014cited by this paper
• Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.) G. Don

  2013cited by this paper
• Support vector machine

  2013cited by this paper
• Treating Type 2 Diabetes Mellitus with Traditional Chinese and Indian Medicinal Herbs

  2013cited by this paper
• The α-amylase and α-glucosidase inhibitory effects of Irish seaweed extracts.

  2013cited by this paper
• KNApSAcK-3D: a three-dimensional structure database of plant metabolites.

  2013cited by this paper
• 11 b-Hydroxysteroid dehydrogenase type 1 : potential therapeutic target for metabolic syndrome

  2012cited by this paper
• The ORCA program system

  2012cited by this paper
• Diabetes in Older Adults: A Consensus Report

  2012cited by this paper
• Protein data bank

  2012cited by this paper
• A Critical Analysis of the Interplay between Cytochrome P450 3A and P-Glycoprotein: Recent Insights from Knockout and Transgenic Mice

  2011cited by this paper
• Open Babel: An open chemical toolbox

  2011cited by this paper
• Insight into the Hypoglycaemic Effect of Traditional Indian Herbs used in the Treatment of Diabetes

  2011cited by this paper
• Natural Products as α-Amylase and α-Glucosidase Inhibitors and their Hypoglycaemic Potential in the Treatment of Diabetes: An Update

  2010cited by this paper
• Antihyperglycemic activity of Catharanthus roseus leaf powder in streptozotocin-induced diabetic rats

  2010cited by this paper
• Oral glucose tolerance test (OGTT) in normal control and glucose induced hyperglycemic rats with Coccinia cordifolia l. and Catharanthus roseus L.

  2009cited by this paper
• AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

  2009cited by this paper
• The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors.

  2009cited by this paper
• Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines.

  2009cited by this paper
• Bioclipse 2: A scriptable integration platform for the life sciences

  2009cited by this paper
• PubChem: Integrated Platform of Small Molecules and Biological Activities

  2008cited by this paper
• New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process

  2008cited by this paper
• Indian Herbs and Herbal Drugs Used for the Treatment of Diabetes

  2007cited by this paper
• DrugBank: a knowledgebase for drugs, drug actions and drug targets

  2007cited by this paper
• ChEBI: a database and ontology for chemical entities of biological interest

  2007cited by this paper
• Bioclipse: an open source workbench for chemo- and bioinformatics

  2007cited by this paper
• The Biochemistry of Drug Metabolism – An Introduction

  2007cited by this paper
• Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.

  2007cited by this paper
• PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.

  2007cited by this paper
• Therapeutic strategies for targeting PTP1B in diabetes

  2005cited by this paper
• Dipeptidyl peptidase IV inhibitors for type 2 diabetes and metabolic syndrome

  2005cited by this paper
• DrugBank: a comprehensive resource for in silico drug discovery and exploration

  2005cited by this paper
• LigandScout: 3-D Pharmacophores Derived from Protein-Bound Ligands and Their Use as Virtual Screening Filters

  2005cited by this paper
• PTP1B inhibitors as potential therapeutics in the treatment of Type 2 diabetes and obesity

  2003cited by this paper
• Dipeptidyl peptidase IV inhibitors for the treatment of impaired glucose tolerance and type 2 diabetes.

  2003cited by this paper
• Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes

  2002cited by this paper
• Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.

  2001cited by this paper
• VMD: visual molecular dynamics.

  1996influential reference
• Pharmacogenetics

  1968cited by this paper

• No citing papers are available for this paper.