Anxiety sensitivity as a predictor of broad dimensions of psychopathology after cognitive behavioral therapy for panic disorder

Background Panic disorder (PD) is a common disease and presents with broad dimensions of psychopathology. Cognitive behavioral therapy (CBT) is known to improve these broad dimensions of psychopathology in addition to PD symptoms. However, little is known about the predictors of treatment response in comorbid psychiatric symptoms after CBT for PD. Recent studies suggest that anxiety sensitivity (AS) may be a key vulnerability for PD. This study aimed to examine AS as a predictor of broad dimensions of psychopathology after CBT for PD. Materials and methods In total, 118 patients with PD were treated with manualized group CBT. We used multiple regression analysis to examine the associations between 3 Anxiety Sensitivity Index (ASI) factors (physical concerns, mental incapacitation concerns, and social concerns) at baseline and the subscales of the Symptom Checklist-90 Revised (SCL-90-R) at endpoint. Results Low levels of social concerns at baseline predicted low levels on 5 SCL-90-R subscales after CBT: interpersonal sensitivity, depression, hostility, paranoid ideation, and psychosis. High levels of mental incapacitation concerns significantly predicted low levels on 3 SCL-90-R subscales after treatment: interpersonal sensitivity, hostility, and paranoid ideation. Physical concerns at baseline did not predict broad dimensions of psychopathology. Conclusion This study suggested that the social concerns and mental incapacitation concerns subscales of the ASI at baseline predicted several dimensions of psychopathology after CBT for PD. To improve comorbid psychopathology, it may be useful to direct more attention to these ASI subscales.

• Publication year

  2017

• Venue

  Neuropsychiatric Disease and Treatment

• Publication date

  2017-07-13

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.2147/NDT.S121360PMID 28761346PMCID 5516871
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Influence of vulnerability factors in panic disorder severity.

  2016influential reference
• Reduction of cognitive concerns of anxiety sensitivity is uniquely associated with reduction of PTSD and depressive symptoms: a comparison of civilians and veterans.

  2014cited by this paper
• Cognitive vulnerability to anxiety in the stress generation process: further investigation of the interaction effect between the looming cognitive style and anxiety sensitivity.

  2013cited by this paper
• Anxiety Sensitivity Index

  2011cited by this paper
• Combined psychotherapy plus benzodiazepines for panic disorder.

  2009cited by this paper
• Anxiety sensitivity as a predictor of the clinical course of panic disorder: a 1‐year follow‐up study

  2009influential reference
• Anxiety sensitivity as an incremental predictor of later anxiety symptoms and syndromes.

  2008cited by this paper
• Reliability and validity of the Japanese version of the Anxiety Sensitivity Index.

  2007influential reference
• Anxiety sensitivity within the anxiety disorders: disorder-specific sensitivities and depression comorbidity.

  2007cited by this paper
• Cognitive behavioral therapy for panic disorder and comorbidity: more of the same or less of more?

  2007influential reference
• Psychotherapy plus antidepressant for panic disorder with or without agoraphobia

  2006cited by this paper
• Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.

  2005cited by this paper
• Cross‐cultural evaluation of the Panic Disorder Severity Scale in Japan

  2004cited by this paper
• Psychopathological correlates of anxiety sensitivity: evidence from clinical interviews and self-report measures.

  2001cited by this paper
• An expanded anxiety sensitivity index: evidence for a hierarchic structure in a clinical sample.

  1998cited by this paper
• The effects of cognitive-behavior therapy for panic disorder on comorbid conditions.

  1998cited by this paper
• Structured clinical interview for DSM-IV axis I disorders : SCID-I: clinical version : administration booklet

  1997cited by this paper
• Multicenter collaborative panic disorder severity scale.

  1997cited by this paper
• Diagnostic comorbidity in panic disorder: effect on treatment outcome and course of comorbid diagnoses following treatment.

  1995cited by this paper
• The Treatment of Anxiety Disorders: Clinician Guides and Patient Manuals

  1995cited by this paper
• Treatment of panic attacks using cognitive therapy without exposure or breathing retraining.

  1991cited by this paper
• Outcome of panic disorder. Relationship to diagnostic subtypes and comorbidity.

  1990cited by this paper
• Anxiety sensitivity, anxiety frequency and the prediction of fearfulness.

  1986cited by this paper
• SCL-90-R, Administration, Scoring, and Procedures Manual-II for the R(evised) Version and Other Instruments of the Psychopathology Rating Scale Series

  1983cited by this paper

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  2025cites this paper
• Gender differences in the transactional associations between anxiety sensitivity and emotion regulation over time

  2023cites this paper
• Treatment Mechanisms, Community Empowerment, & Technology Innovations (TCT) Lab

  2022cites this paper
• Potential Predictors of Virtual Reality Exposure Therapy for Fear of Flying: Anxiety Sensitivity, Self-efficacy and the Therapeutic Alliance

  2022cites this paper
• Testing Clinical Intuitions About Barriers to Improvement in Cognitive-Behavioral Therapy for Panic Disorder.

  2021cites this paper
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  2020cites this paper
• Anxiety sensitivity and emotion regulation as mechanisms of successful CBT outcome for anxiety-related disorders in a naturalistic treatment setting.

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• Sensitividad Ansiosa y Afecto Negativo: Modelo transdiagnóstico para síntomas ansiosos y depresivos

  2019cites this paper
• Anxiety sensitivity does not predict treatment outcome or treatment length in obsessive-compulsive disorder and related anxiety disorders

  2019cites this paper
• Assessing anxiety sensitivity

  2019cites this paper
• Predictors of Broad Dimensions of Psychopathology among Patients with Panic Disorder after Cognitive-Behavioral Therapy

  2018cites this paper
• Treatment-Resistant Panic Disorder

  2018cites this paper
• Investigating effective treatment factors in brief cognitive behavioral therapy for panic disorder

  2018influential citation