Role of Agmatine on Neuroglia in Central Nervous System Injury

Sumit Barua,Jong Youl Kim,J. E. Lee

Published 2019 in Brain & Neurorehabilitation

ABSTRACT

• The primary amine agmatine is neuroprotective after central nervous system (CNS) injury. • The agmatine downregulates the astrogliosis following the CNS injury. • Agmatine attenuates the detrimental effects of activated microglia in CNS injury. • Agmatine regulates the astrogliosis and microgliosis via modulating the bone morphogenic proteins expression. Brain Neurorehabil. 2019 Mar;12(1):e2 https://doi.org/10.12786/bn.2019.12.e2 pISSN 1976-8753·eISSN 2383-9910

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