Modulatory Sites Associated with the GABA Receptor-lonophore Complex and the Development of New, Potentially Specific Therapeutic Agents

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-1-4613-0925-3_13
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• ZK 91296, a partial agonist at benzodiazepine receptors

  2004cited by this paper
• β-Carbolines can enhance or antagonize the effects of punishment in mice

  2004cited by this paper
• Handbook of Psychopharmacology

  1988cited by this paper
• Bidirectional effects of β-carbolines and benzodiazepines on cognitive processes

  1987cited by this paper
• Bidirectional effects of beta-carbolines in rats with spontaneous petit mal-like seizures.

  1987cited by this paper
• Enhancement of performance by methyl β-carboline-3-carboxylate, in learning and memory tasks

  1987cited by this paper
• Electrophysiological studies in cultured mouse CNS neurones of the actions of an agonist and an inverse agonist at the benzodiazepine receptor

  1986cited by this paper
• Bidirectional modulation of GABA function by beta-carbolines.

  1986cited by this paper
• New Perspectives in Benzodiazepine Receptor Pharmacology

  1986cited by this paper
• Effects of methyl beta-carboline-3-carboxylate, Ro 15-1788 and CGS 8216 on muscle tone in genetically spastic rats.

  1985cited by this paper
• On the location of γ-aminobutyrate and benzodiazepine receptors in the cerebellum of the normal C3H and Lurcher mutant mouse

  1985cited by this paper
• Radiation inactivation of brain [35S]t-butylbicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.

  1985cited by this paper
• The GABA-ergic system: a locus of benzodiazepine action.

  1985cited by this paper
• Evaluation of the muscle relaxant properties of a novel β‐carboline, ZK 93423 in rats and cats

  1985cited by this paper
• ZK 91296, an anticonvulsant β-carboline which lacks muscle relaxant properties

  1985cited by this paper
• Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

  1985cited by this paper
• GABAB receptors: has adenylate cyclase inhibition any functional relevance?

  1984cited by this paper
• Properties of [3H]diazepam binding sites on cultured murine glia and neurons.

  1984cited by this paper
• Modulation of the responses to the GABA-mimetics, THIP and piperidine-4-sulphonic acid, by agents which interact with benzodiazepine receptors. An electrophysiological study on cultured mouse neurones.

  1984cited by this paper
• Modulation of Neuronal Function through Benzodiazepine Receptors: Biochemical and Electrophysiological Studies of Neurons in Primary Monolayer Cell Culture

  1984cited by this paper
• Proconflict effect of benzodiazepine receptor inverse agonists and other inhibitors of GABA function.

  1984cited by this paper
• Benzodiazepine receptor ligands with positive and negative efficacy.

  1983cited by this paper
• Convulsant‐induced depression of amino acid responses in cultured mouse spinal neurones studied under voltage clamp

  1983cited by this paper
• Anxiogenic and non-anxiogenic benzodiazepine antagonists

  1983cited by this paper
• Properties of [3H]flunitrazepam binding to different benzodiazepine binding proteins.

  1983cited by this paper
• SEVERE ANXIETY INDUCED BY FG 7142, A β-CARBOLINE LIGAND FOR BENZODIAZEPINE RECEPTORS

  1983cited by this paper
• Diazepam stimulates the binding of GABA and muscimol but not THIP to rat brain membranes.

  1983cited by this paper
• Anticonvulsant action in the photosensitive baboon, Papio papio, of a novel beta-carboline derivative, ZK 91296.

  1983cited by this paper
• Binding of [3H]DMCM, a Convulsive Benzodiazepine Ligand, to Rat Brain Membranes: Preliminary Studies

  1983cited by this paper
• Audiogenic seizures in DBA/2 mice discriminate sensitively between low efficacy benzodiazepine receptor agonists and inverse agonists.

  1983cited by this paper
• Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.

  1983cited by this paper
• beta-Carbolines enhance shock-induced suppression of drinking in rats.

  1983cited by this paper
• DMCM: a potent convulsive benzodiazepine receptor ligand.

  1983cited by this paper
• Differential pharmacological effects of benzodiazepine receptor inverse agonists.

  1983cited by this paper
• Benzodiazepine recognition site ligands : biochemistry and pharmacology

  1983cited by this paper
• Benzodiazepine receptors: differential interaction of benzodiazepine agonists and antagonists after photoaffinity labeling with flunitrazepam.

  1982cited by this paper
• Diazepam enhancement of low affinity GABA binding to rat brain membranes.

  1982cited by this paper
• Drug interactions at the GABA receptor-ionophore complex.

  1982cited by this paper
• Unusual interactions of benzodiazepine receptor antagonists

  1982cited by this paper
• Benzodiazepine receptor-mediated experimental "anxiety" in primates.

  1982cited by this paper
• Modulation of GABA binding to rat brain membranes by alkyl beta-carboline-3-carboxylate esters.

  1982cited by this paper
• A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, β-carbolines, and phenobarbitone

  1982cited by this paper
• Interaction of convulsive ligands with benzodiazepine receptors.

  1982cited by this paper
• Investigation in man of the efficacy of a benzodiazepine antagonist, Ro 15-1788.

  1981cited by this paper
• Biochemical identification of pharmacologically and functionally distinct GABA receptors in rat brain

  1981cited by this paper
• Benzodiazepine binding and interactions with the GABA receptor complex in living cultures of rat cerebral cortex.

  1981cited by this paper
• Dihydropicrotoxinin binding sites in mammalian brain: interaction with convulsant and depressant benzodiazepines.

  1981cited by this paper
• Selective antagonists of benzodiazepines

  1981cited by this paper
• The interaction between barbiturate anaesthetics and excitatory amino acid responses on cat spinal neurones.

  1981cited by this paper
• Agonist and antagonist benzodiazepine receptor interaction in vitro

  1981cited by this paper
• Chlordiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture.

  1981cited by this paper
• Autoradiographic localization of benzodiazepine receptors in immunocytochemically identified gamma-aminobutyrergic synapses.

  1981cited by this paper
• Ethyl β-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats

  1981cited by this paper
• Pentobarbital: dual actions to increase brain benzodiazepine receptor affinity.

  1981cited by this paper
• Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons.

  1981cited by this paper
• Proconvulsant effects in baboons of β-carboline, a putative endogenous ligand for benzodiazepine receptors

  1981cited by this paper
• [3H]Diazepam binding in mammalian central nervous system: a pharmacological characterization

  1981cited by this paper
• Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study.

  1981cited by this paper
• Enhancement of GABA binding by pentobarbitone.

  1980cited by this paper
• Urinary and brain beta-carboline-3-carboxylates as potent inhibitors of brain benzodiazepine receptors.

  1980cited by this paper
• Properties of [3H]diazepam binding sites on rat blood platelets.

  1980cited by this paper
• Electrophysiological studies of the mode of action of GABA on vertebrate central neurons.

  1980cited by this paper
• β-Carboline-3-carboxylic acid ethyl ester antagonizes diazepam activity

  1980cited by this paper
• Evidence that bicuculline and picrotoxin act at separate sites to antagonize gamma-aminobutyric acid in rat cuneate nucleus.

  1980cited by this paper
• The proconvulsant and diazepam-reversing effects of ethyl-beta-carboline-3-carboxylate.

  1980cited by this paper
• Characterization of benzodiazepine receptors in primary cultures of fetal mouse brain and spinal cord neurons.

  1980cited by this paper
• Partial agonists for brain GABA/benzodiazepine receptor complex

  1979cited by this paper
• Some properties of brain specific benzodiazepine receptors: new evidence for multiple receptors.

  1979cited by this paper
• Neuronal localisation of benzodiazepine receptors in cerebellum.

  1979cited by this paper
• Some properties of 3H-diazepam displacing activity from human urine.

  1979cited by this paper
• Pharmacological characterization of different types of GABA and glutamate receptors in vertebrates and invertebrates.

  1979cited by this paper
• Is the benzodiazepine receptor coupled to a chloride anion channel?

  1979cited by this paper
• Is stimulation of benzodiazepine receptor binding mediated by a novel GABA receptor?

  1979cited by this paper
• The Benzodiazepine Receptor in Normal and Pathological Human Brain

  1978cited by this paper
• Amino acid pharmacology of mammalian central neurones grown in tissue culture.

  1978cited by this paper
• Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture.

  1978cited by this paper
• Autoradiographic localization of γ-aminobutyric acid receptors in the rat central nervous system by using [3H]muscimol

  1978cited by this paper
• Brain Specific Benzodiazepine Receptors

  1978cited by this paper
• Interaction of barbiturates with dihydropicrotoxinin binding sites related to the GABA receptor-ionophore system.

  1978cited by this paper
• Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones

  1978cited by this paper
• GABAergic modulation of benzodiazepine binding site sensitivity

  1978cited by this paper
• Benzodiazepine receptors in rat brain

  1977cited by this paper
• t-Butyl bicyclo phosphate: a convulsant and GABA antagonist more potent than bicuculline [proceedings].

  1977cited by this paper
• GABA receptor binding with 3H (+) bicuculline–methiodide in rat CNS

  1977cited by this paper
• Effects of two benzodiazepines, phenobarbitone, and baclofen on synaptic transmission in the cat cuneate nucleus

  1976cited by this paper
• Rachitogenicity of Green Oats

  1950cited by this paper
• The Antecedents of Cancer

  1867cited by this paper

• Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABAA receptor partial agonist, 4-PIOL.

  1996cites this paper
• Stimulation of cortical acetylcholine efflux by FG 7142 measured with repeated microdialysis sampling

  1995cites this paper
• Electrophysiological studies of the GABAA receptor ligand, 4‐PIOL, on cultured hippocampal neurones

  1991cites this paper