Cyclic AMP-dependent protein kinase but not protein kinase C regulates the cardiac Ca2+ channel through phosphorylation of its alpha 1 subunit.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Journal of Biochemistry (Tokyo)

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 8864860
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphorylation of Ion channels

  2005cited by this paper
• Subunit structure and phosphorylation of the cardiac L-type calcium channel.

  1994cited by this paper
• Protein kinase C-mediated regulation of L-type Ca channels from skeletal muscle requires phosphorylation of the alpha 1 subunit.

  1994cited by this paper
• Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells.

  1994cited by this paper
• Phosphorylation of the L-type calcium channel beta subunit is involved in beta-adrenergic signal transduction in canine myocardium.

  1993cited by this paper
• Cyclic AMP‐Dependent Phosphorylation and Regulation of the Cardiac Dihydropyridine‐Sensitive Ca Channel

  1993cited by this paper
• Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase.

  1992cited by this paper
• Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel.

  1992cited by this paper
• Structural characterization of the dihydropyridine receptor-linked calcium channel from porcine heart.

  1992cited by this paper
• Purification of the cardiac 1,4-dihydropyridine receptor using immunoaffinity chromatography with a monoclonal antibody against the alpha 2 delta subunit of the skeletal muscle dihydropyridine receptor.

  1992cited by this paper
• Synergism between cAMP and ATP in signal transduction in cardiac myocytes.

  1992cited by this paper
• A Gs protein couples P2-purinergic stimulation to cardiac Ca channels without cyclic AMP production

  1992cited by this paper
• β-Subunit expression is required for cAMP-dependent increase of cloned cardiac and vascular calcium channel currents

  1992cited by this paper
• A rapid procedure for the purification of cardiac 1,4-dihydropyridine receptors from porcine heart.

  1991cited by this paper
• The roles of the subunits in the function of the calcium channel.

  1991cited by this paper
• Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels.

  1991cited by this paper
• Dihydropyridine-sensitive calcium channels from skeletal muscle. II. Functional effects of differential phosphorylation of channel subunits.

  1991cited by this paper
• Molecular characterization of 1,4-dihydropyridine-sensitive calcium channels of chick heart and skeletal muscle.

  1990cited by this paper
• Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells.

  1990cited by this paper
• Activation of purified calcium channels by stoichiometric protein phosphorylation.

  1989cited by this paper
• Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

  1989cited by this paper
• Modulation of ion channel activity: a key function of the protein kinase C enzyme family.

  1989cited by this paper
• Regulation of a heart potassium channel by protein kinase A and C.

  1988cited by this paper
• Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel.

  1988cited by this paper
• Phorbol Ester Increases Calcium Current and Simulates the Effects of Angiotensin II on Cultured Neonatal Rat Heart Myocytes

  1988cited by this paper
• Dihydropyridine and phenylalkylamine receptors associated with cardiac and skeletal muscle calcium channels are structurally different.

  1988cited by this paper
• The bovine cardiac receptor for calcium channel blockers is a 195-kDa protein.

  1988cited by this paper
• Mode of activation and kinetic properties of three distinct forms of protein kinase C from rat brain.

  1988cited by this paper
• Phosphorylation of the 165-kDa dihydropyridine/phenylalkylamine receptor from skeletal muscle by protein kinase C.

  1988cited by this paper
• Calcium efflux through cardiac calcium channels reconstituted into liposomes--flux measurement with fura-2.

  1988cited by this paper
• Calcium channels: Molecular pharmacology, structure and regulation

  1988cited by this paper
• Effects of protein kinase C activators on cardiac Ca2+ channels

  1988cited by this paper
• Multiple types of neuronal calcium channels and their selective modulation.

  1988cited by this paper
• The heterogeneity of protein kinase C in various rat tissues.

  1988cited by this paper
• Regulation of calcium slow channels of cardiac muscle by cyclic nucleotides and phosphorylation.

  1988cited by this paper
• Phosphorylation of the purified receptor for calcium channel blockers by cAMP kinase and protein kinase C.

  1987cited by this paper
• Photoaffinity labelling of the cardiac calcium channel. (-)-[3H]azidopine labels a 165 kDa polypeptide, and evidence against a [3H]-1,4-dihydropyridine-isothiocyanate being a calcium-channel-specific affinity ligand.

  1987cited by this paper
• Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel

  1986cited by this paper
• Rapid purification of protein kinase C by high performance liquid chromatography.

  1986cited by this paper
• Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase.

  1985cited by this paper
• Ion channels in cardiac cell membranes.

  1984cited by this paper

• Methods of reconstitution to investigate membrane protein function.

  2018cites this paper
• Regulation of cardiac L-type Ca²⁺ channel CaV1.2 via the β-adrenergic-cAMP-protein kinase A pathway: old dogmas, advances, and new uncertainties.

  2013cites this paper
• The Heart: A Novel Gonadotrophin‐Releasing Hormone Target

  2011cites this paper
• Chronic morphine treatment decreases the Cav1.3 subunit of the L-type calcium channel.

  2008cites this paper
• Channel phosphorylation and modulation of L-type Ca2+ currents by cytosolic Mg2+ concentration.

  2006cites this paper
• Channel phosphorylation and modulation of L-type calcium currents by cytosolic magnesium ion concentration

  2006cites this paper
• Regulation of L-type Ca2+ channels in the heart: Overview of recent advances

  2003cites this paper
• Effect of hydrogen peroxide on the membrane currents of sinoatrial node cells from rabbit heart.

  2000cites this paper
• Regulation of Ion Channels in Myocardial Cells and Protection of Ischemic Myocardium

  2000cites this paper
• Signaling from β‐adrenoceptor to L‐type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK

  1999cites this paper
• Cardiac protein phosphorylation: functional and pathophysiological correlates.

  1998cites this paper
• The autonomic nervous system and the heart

  1997cites this paper
• Special Topic: Calcium Signaling Membrane Protein Reconstitution for Functional and Structural Studies

  year unknowncites this paper