Poliovirus Polymerase

Abstract This chapter describes structure and function of poliovirus RNA-dependent RNA polymerase (RdRP). It starts by providing the perspective for the need of antipolio drugs along with the various targets for the discovery of such drugs. A highlight is then presented on the importance RdRP of the virus in the development of drugs against it, followed by the discussion on the various inhibitors of the enzyme discovered till date and the challenges encountered in their designing and biological evaluation. The chapter concludes with a future perspective in the discovery of novel drug molecules against polio.

• Publication year

  2019

• Venue

  Viral Polymerases

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/B978-0-12-815422-9.00005-X
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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