Separation of phospholipid molecular species by high performance liquid chromatography: potentials for use in metabolic studies.

Different molecular species of phospholipids exhibit distinctly different patterns of biologic behavior. In this minireview, the utility of HPLC for analysis of molecular species of phospholipids is illustrated in studies in which it has been demonstrated that molecular species are selectively synthesized, selectively transported, and selectively participate in enzymatic reactions. HPLC appears to be more adaptable for routine use than older procedures used to separate phospholipid molecular species. Since the metabolism of intact molecules can be characterized with HPLC, this procedure promises to provide particularly novel information with respect to changes in composition brought about by remodelling reactions during the biologic life of specific phospholipids.

• Publication year

  1986

• Venue

  Journal of Lipid Research

• Publication date

  1986-02-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0022-2275(20)38844-1PMID 3958616
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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