Dissecting the in vivo leukemogenic potency of BCLxl.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Leukemia

• Publication date

  2014-09-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4172/2329-6917.1000158PMID 26636115PMCID PMC4666309
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

  2014cited by this paper
• Ubiquilin1 Represses Migration and Epithelial to Mesenchymal Transition of Human Non-small Cell Lung Cancer Cells

  2014cited by this paper
• Structural biology of the Bcl-2 family and its mimicry by viral proteins

  2013influential reference
• The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein interactions with Bak

  2013cited by this paper
• Mechanisms of action of Bcl-2 family proteins.

  2013cited by this paper
• Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-Like Proteins

  2013cited by this paper
• Oncogenic driver supersedes BM preparation as the critical determinant of leukemic outcome: a one day protocol for BM harvest, infection and transplantation

  2013cited by this paper
• Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis

  2012cited by this paper
• Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1

  2012cited by this paper
• The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment.

  2011cited by this paper
• MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family

  2009cited by this paper
• Bcl2 family proteins in carcinogenesis and the treatment of cancer

  2009cited by this paper
• Bcl-2 family proteins and cancer

  2008cited by this paper
• ‘Seed’ analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737

  2007cited by this paper
• A novel Bcl-2/Bcl-XL/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma

  2007cited by this paper
• Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma

  2007cited by this paper
• New Approaches and Therapeutics Targeting Apoptosis in Disease

  2005cited by this paper
• Apoptosis in the development and treatment of cancer.

  2004cited by this paper
• BH4-domain peptide from Bcl-xL exerts anti-apoptotic activity in vivo

  2003cited by this paper
• Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance

  2003cited by this paper
• BAX and BAK Regulation of Endoplasmic Reticulum Ca2+: A Control Point for Apoptosis

  2003cited by this paper
• Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells.

  2000cited by this paper
• Apoptosis signaling.

  2000cited by this paper
• BCL-2 family members and the mitochondria in apoptosis.

  1999cited by this paper
• Bcl-2 family proteins and mitochondria.

  1998cited by this paper
• Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases.

  1997cited by this paper
• Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.

  1996cited by this paper
• Bcl-XL protects cancer cells from p53-mediated apoptosis.

  1995cited by this paper

• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.

  2024cites this paper
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  2023influential citation
• Characterization of a more clinically relevant human leukemia xenograft model to examine perturbation of MET/SAM metabolism as a novel therapeutic paradigm for MLL-R leukemia in vivo.

  2019cites this paper
• Design and Success of a 21st Century Cancer Education Program at the University of Louisville

  2018cites this paper
• Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response.

  2018cites this paper
• Cancer Metastasis and its Suppressor Genes

  2017cites this paper
• Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.

  2017cites this paper
• Looking at Bacterial Behaviour in Our Body: Probiotics

  2015cites this paper