Measurement of Total and Unbound Mycophenolic Acid and Its Glucuronide by LC Coupled with MS. Application to a Pharmacokinetic Study of Mycophenolate Mofetil in Patients with Autoimmune Diseases

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Chromatographia

• Publication date

  2009-08-23

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1365/S10337-009-1223-8
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Measurement of mycophenolic acid and its glucuronide using a novel rapid liquid chromatography-electrospray ionization tandem mass spectrometry assay.

  2009cited by this paper
• Clinical Pharmacokinetics and Pharmacodynamics of Mycophenolate in Solid Organ Transplant Recipients

  2007cited by this paper
• Simple reversed-phase liquid chromatographic assay for simultaneous quantification of free mycophenolic acid and its glucuronide metabolite in human plasma.

  2007cited by this paper
• Sensitive high-performance liquid chromatography-tandem mass spectrometry method for quantitative analysis of mycophenolic acid and its glucuronide metabolites in human plasma and urine.

  2007cited by this paper
• Relationship between MPA free fraction and free MPAG concentrations in heart transplant recipients based on simultaneous HPLC quantification of the target compounds in human plasma.

  2007cited by this paper
• Pharmacokinetics of Mycophenolate Mofetil in Hematopoietic Stem Cell Transplant Recipients

  2007cited by this paper
• Individualized Mycophenolate Mofetil Dosing Based on Drug Exposure Significantly Improves Patient Outcomes After Renal Transplantation

  2007cited by this paper
• Total and free mycophenolic acid and its 7-O-glucuronide metabolite in Chinese adult renal transplant patients: pharmacokinetics and application of limited sampling strategies

  2006cited by this paper
• Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasma.

  2005cited by this paper
• Quantification of mycophenolic acid and glucuronide metabolite in human serum by HPLC-tandem mass spectrometry.

  2005cited by this paper
• Simultaneous determination of mycophenolic acid and its phenolic glucuronide in human plasma using an isocratic high-performance liquid chromatography procedure.

  2005cited by this paper
• Determination of mycophenolic acid in human plasma by high-performance liquid chromatography.

  2004cited by this paper
• Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid.

  2004cited by this paper
• HPLC determination of mycophenolic acid and mycophenolic acid glucuronide in human plasma with hybrid material.

  2004cited by this paper
• Determination of the immunosuppressant mycophenolic acid in human serum by solid-phase microextraction coupled to liquid chromatography.

  2004cited by this paper
• Mycophenolates in transplantation

  2004cited by this paper
• Comparison of Liquid Chromatography-Tandem Mass Spectrometry with a Commercial Enzyme-Multiplied Immunoassay for the Determination of Plasma MPA in Renal Transplant Recipients and Consequences for Therapeutic Drug Monitoring

  2004cited by this paper
• Quantification of free mycophenolic acid and its glucuronide metabolite in human plasma by liquid-chromatography using mass spectrometric and ultraviolet absorbance detection.

  2004cited by this paper
• Development of a high pressure liquid chromatography method for the determination of mycophenolic acid and its glucuronide metabolite in small volumes of plasma from paediatric patients.

  2004cited by this paper
• Automated Determination of Free Mycophenolic Acid and Its Glucuronide in Plasma From Renal Allograft Recipients

  2003cited by this paper
• Rapid determination of mycophenolic acid in plasma by reversed-phase high-performance liquid chromatography.

  2002cited by this paper
• Mycophenolate mofetil and its mechanisms of action.

  2000cited by this paper
• Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and Emit.

  2000cited by this paper
• Clinical Pharmacokinetics of Mycophenolate Mofetil

  1998cited by this paper
• Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure.

  1998cited by this paper

• Rapid Separation and Screening of Mycophenolate Mofetil and Mycophenolic Acid with a Novel (Vinyl Ester) Resin Molecular Imprinted Monolithic Column

  2020cites this paper
• Free mycophenolic acid determination in human plasma ultrafiltrate by a validated liquid chromatography-tandem mass spectrometry method.

  2017cites this paper
• Pre-dose plasma concentration monitoring of mycophenolate mofetil in patients with autoimmune diseases.

  2014cites this paper
• Determination of Mycophenolic acid in the vitreous humor using the HPLC-ESI-MS/MS method: application of intraocular pharmacokinetics study in rabbit eyes with ophthalmic implantable device.

  2013cites this paper
• Steady-state mycophenolate mofetil pharmacokinetic parameters enable prediction of systemic lupus erythematosus clinical flares: an observational cohort study

  2010cites this paper
• Determination of mycophenolic acid and its phenyl glucuronide in human plasma, ultrafiltrate, blood, DBS and dried plasma spots.

  2010cites this paper
• Therapeutic drug monitoring of mycophenolate mofetil and enteric-coated mycophenolate sodium in patients with systemic lupus erythematosus

  2010cites this paper