APOE genotype, lipids, and coronary heart disease risk: a prospective population study.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Archives of Internal Medicine

• Publication date

  2009-08-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1001/archinternmed.2009.234PMID 19667307
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Exercise as a Mean to Control Low-Grade Systemic Inflammation

  2009cited by this paper
• The Colon Health and Life-Long Exercise Change trial: a randomized trial of the National Cancer Institute of Canada Clinical Trials Group

  2008cited by this paper
• ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation

  2007cited by this paper
• Association of apolipoprotein E genotypes with lipid levels and coronary risk.

  2007influential reference
• Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study.

  2007cited by this paper
• Plasma C-Reactive Protein and Risk of Colorectal Cancer in a Nested Case-Control Study: Japan Public Health Center–Based Prospective Study

  2006cited by this paper
• Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.

  2006cited by this paper
• Systemic therapy for colorectal cancer.

  2005cited by this paper
• [Systemic therapy for colorectal cancer].

  2005cited by this paper
• The Significant Increase in Cardiovascular Disease Risk in APOEɛ4 Carriers is Evident Only in Men Who Smoke: Potential Relationship Between Reduced Antioxidant Status and ApoE4

  2005cited by this paper
• Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study.

  2004cited by this paper
• Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk.

  2004cited by this paper
• No APOEepsilon4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II study.

  2004cited by this paper
• Quality of life in patients with colorectal cancer 1 year after diagnosis compared with the general population: a population-based study.

  2004cited by this paper
• The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study).

  2004cited by this paper
• Prognostic importance of comorbidity in a hospital-based cancer registry.

  2004cited by this paper
• No APOEε4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II study

  2004cited by this paper
• Meta-Analysis: Apolipoprotein E Genotypes and Risk for Coronary Heart Disease

  2004cited by this paper
• Methodological problems in genetic association studies of longevity--the apolipoprotein E gene as an example.

  2004cited by this paper
• Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E epsilon2/epsilon3/epsilon4 genotype.

  2003cited by this paper
• Validity and repeatability of a simple index derived from the short physical activity questionnaire used in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

  2003cited by this paper
• In search of genetic precision. Authors' reply

  2003cited by this paper
• Apolipoprotein E Polymorphism and Atherosclerosis

  2003cited by this paper
• A prospective study of the association between APOE genotype and the risk of myocardial infarction among apparently healthy men.

  2003cited by this paper
• Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E ε2/ε3/ε4 genotype

  2003cited by this paper
• In search of genetic precision.

  2003cited by this paper
• Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden

  2002cited by this paper
• Apolipoprotein E polymorphism affects carotid artery atherosclerosis in smoking hypertensive men

  2002cited by this paper
• Influence of Apolipoprotein E, Smoking, and Alcohol Intake on Carotid Atherosclerosis: National Heart, Lung, and Blood Institute Family Heart Study

  2002cited by this paper
• Physical activity and cancer prevention: etiologic evidence and biological mechanisms.

  2002cited by this paper
• Evidence of reduced coronary artery disease risk for apolipoprotein epsilon2/3 heterozygotes.

  2002cited by this paper
• Socioeconomic and demographic disparities in treatment for carcinomas of the colon and rectum

  2002cited by this paper
• Evidence of reduced coronary artery disease risk for apolipoprotein ϵ2/3 heterozygotes

  2002cited by this paper
• Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study.

  2001cited by this paper
• Physical activity and cancer prevention: from observational to intervention research.

  2001cited by this paper
• Is the apoE4 allele an independent predictor of coronary events?

  2001cited by this paper
• Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study.

  2001cited by this paper
• A prospective study of plasma levels of insulin-like growth factor I (IGF-I) and IGF-binding protein-3, and colorectal cancer risk among men.

  2000cited by this paper
• The New England Journal

  2000cited by this paper
• C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.

  2000cited by this paper
• Apolipoprotein E genotype: epsilon32 women are protected while epsilon43 and epsilon44 men are susceptible to ischemic heart disease: the Copenhagen City Heart Study.

  2000cited by this paper
• Influence of hospital procedure volume on outcomes following surgery for colon cancer.

  2000cited by this paper
• Apolipoprotein E: far more than a lipid transport protein.

  2000cited by this paper
• Smoking and cardiovascular disease.

  2000cited by this paper
• Response: More About: Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF- Binding Protein-3

  1999cited by this paper
• Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

  1999cited by this paper
• Comparison of the LDL-receptor binding of VLDL and LDL from apoE4 and apoE3 homozygotes.

  1999cited by this paper
• IGF‐I and IGF‐II in relation to colorectal cancer

  1999cited by this paper
• EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer.

  1999influential reference
• Apolipoprotein E genotype modulates the effect of black tea drinking on blood lipids and blood coagulation factors: a pilot study

  1998cited by this paper
• Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients

  1998cited by this paper
• Apolipoprotein E alleles and risk of coronary disease. A meta-analysis.

  1996cited by this paper
• The influence of other diseases upon the outcome of colorectal cancer patients.

  1995cited by this paper
• Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study.

  1994cited by this paper
• Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction. The ECTIM Study.

  1994cited by this paper
• Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study.

  1994cited by this paper
• Smoking and cardiovascular disease.

  1992cited by this paper
• Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis.

  1992cited by this paper
• Cholesterol absorption, elimination, and synthesis related to LDL kinetics during varying fat intake in men with different apoprotein E phenotypes.

  1992cited by this paper
• Apolipoprotein E polymorphism and atherosclerosis.

  1988cited by this paper
• Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.

  1985cited by this paper
• Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.

  1982cited by this paper
• Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

  1972cited by this paper

• The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

  2025cites this paper
• Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study

  2024cites this paper
• Assessment Outcomes Effect of Apolipoprotein E4 Allele on Cardiovascular Diseases

  2024cites this paper
• Relationships Between APOE, Type 2 Diabetes, and Cardiovascular Disease in Postmenopausal Women

  2024cites this paper
• Apolipoprotein E-ε2 and Resistance to Atherosclerosis in Midlife: The PESA Observational Study

  2024cites this paper
• Genetic Polymorphisms and Genetic Risk Scores Contribute to the Risk of Coronary Artery Disease (CAD) in a North Indian Population

  2024cites this paper
• Association of epistatic effects of MTHFR, ACE, APOB, and APOE gene polymorphisms with the risk of myocardial infarction and unstable angina in Egyptian patients.

  2023cites this paper
• Effect of ApoE ε4 gene polymorphism on the correlation between serum uric acid and left ventricular hypertrophy remodeling in patients with coronary heart disease

  2022cites this paper
• Longitudinal association of Apolipoprotein E polymorphism with lipid profile, type 2 diabetes and metabolic syndrome: Results from a 15 year follow-up study.

  2022cites this paper
• Examining the effects of the CLU and APOE polymorphisms' combination on coronary artery disease complexed with type 2 diabetes mellitus.

  2021cites this paper
• Associations between Apolipoprotein E Gene Polymorphism, Diet and Dyslipidemia in a Yao Minority Area, China.

  2021cites this paper
• The rs429358 Locus in Apolipoprotein E Is Associated With Hepatocellular Carcinoma in Patients With Cirrhosis

  2021cites this paper
• Mediation of the APOE associations with Alzheimer’s and coronary heart diseases through body mass index and lipids

  2021cites this paper
• DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health

  2020cites this paper
• Genetic polymorphisms in early-onset myocardial infarction in a sample of Iraqi patients: a pilot study

  2020cites this paper
• Association between apolipoprotein E gene polymorphism and the risk of coronary artery disease in Hakka postmenopausal women in southern China

  2020cites this paper
• DNA methylation in the APOE gene: its link with Alzheimer’s and cardiovascular health

  2019cites this paper
• A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward.

  2019cites this paper
• Association between APOE polymorphisms and lipid profile in Mexican Amerindian population

  2019cites this paper
• Gene Polymorphisms of Methylenetetrahydrofolate Reductase and Apolipoprotein E: Causes or Markers for Coronary Artery Disease?

  2019cites this paper
• Apolipoprotein E2 Genotype Is Associated with a 2-Fold Increase in the Incidence of Type 2 Diabetes Mellitus: Results from a Long-Term Observational Study

  2019cites this paper
• ASSOCIATION OF GENETIC VARIATION AND LIPID-RELATED CONCENTRATIONS IN AFRICAN AMERICAN MEN WITH AND WITHOUT TYPE 2 DIABETES

  2018cites this paper
• Effects of polymorphisms in APOB, APOE, HSD11β1, PLIN4, and ADIPOQ genes on lipid profile and anthropometric variables related to obesity in children and adolescents

  2018cites this paper
• IMPACT OF APOE 2 ALLELE ON LIPID PROFILE CHANGE AFTER A WEIGHT LOSS PROGRAM EXERCISE

  2018cites this paper
• Analysis of SLCO1B1 and APOE genetic polymorphisms in a large ethnic Hakka population in southern China

  2018cites this paper
• The T2238C Human Atrial Natriuretic Peptide Molecular Variant and the Risk of Cardiovascular Diseases

  2018cites this paper
• APOE Gene polymorphism among Jordanian Alzheimer’s patients with relation to lipid profile

  2018cites this paper
• Apolipoprotein E: the resilience gene

  2017cites this paper
• Association of APOE gene polymorphism with lipid profile and coronary artery disease in Afro-Caribbeans

  2017cites this paper
• Genetic Research and Women’s Heart Disease: a Primer

  2016cites this paper
• Serum apolipoprotein E concentration and polymorphism influence serum lipid levels in Chinese Shandong Han population

  2016cites this paper
• The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial.

  2016cites this paper
• Association of ApoE4 genotypes, peripheral arterial disease and cardiovascular complications among a cohort of elderly diabetic Egyptian patients: A case–control study

  2016cites this paper
• Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders

  2016cites this paper
• Prevalencia de factores de riesgo cardiovascular asociados a marcadores genéticos en población andaluza

  2016influential citation
• The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial1

  2016cites this paper
• Apolipoprotein E gene polymorphisms in relation to chronic periodontitis, periodontopathic bacteria, and lipid levels.

  2015cites this paper
• Candidate Gene–Environment Interaction Research

  2015cites this paper
• Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations

  2015influential citation
• Relation between Apolipoprotein E Gene Polymorphism and Severity of Coronary Artery Disease in Acute Myocardial Infarction

  2015cites this paper
• C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro

  2015cites this paper
• Selenium Level and Dyslipidemia in Rural Elderly Chinese

  2015cites this paper
• APOE Gene Polymorphism and Risk of Coronary Stenosis in Pakistani Population

  2015cites this paper
• Genes, lifestyle and coronary heart disease risk-epidemiological interaction studies

  2015cites this paper
• The Intersection of Genomics of Cardiometabolic Disease and Eye Health

  2015cites this paper
• Study of Apolipoprotein E Polymorphism as a Biomarker in Coronary Artery Diseases

  2014cites this paper
• Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes

  2014cites this paper
• APOE2 enhances neuroprotection against Alzheimer’s disease through multiple molecular mechanisms

  2014cites this paper
• CASE REPORT OF A PATIENT WITH RARE P.ARG136CYS (APOE2*) MUTATION IN APOLIPOPROTEIN E GENE

  2014cites this paper
• Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study

  2014cites this paper
• Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Is It Contributing to Higher Risk of Cognitive Decline and Coronary Heart Disease?

  2014cites this paper
• Sources of adverse selection in insurance markets with genetic information

  2014cites this paper
• Adverse selection in a start-up long-term care insurance market

  2014cites this paper
• Genetic variation at the CELF1 (CUGBP, elav‐like family member 1 gene) locus is genome‐wide associated with Alzheimer's disease and obesity

  2014cites this paper
• Smoking, apolipoprotein E genotypes, and mortality (the Ludwigshafen RIsk and Cardiovascular Health study).

  2013cites this paper
• Association between APOE, SCARB1, PPARα polymorphisms and serum lipids in a population of Lithuanian adults

  2013cites this paper
• Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

  2013cites this paper
• How Genetic Transmission Works

  2013cites this paper
• The number of cysteine residues per mole in apolipoprotein E affects systematically synchronous neural interactions in women’s healthy brains

  2013cites this paper
• Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.

  2013cites this paper
• Response of serum lipids to a fat meal in Black South African subjects with different apoe genotypes

  2013influential citation
• Genetic contributions to cognitive ageing and structural brain magnetic resonance imaging phenotypes

  2013cites this paper
• APOLIPOPROTEIN E GENE POLYMORPHISM, ALCOHOL USE, AND THEIR INTERACTIONS IN COMBAT‐RELATED POSTTRAUMATIC STRESS DISORDER

  2013cites this paper
• Does Apolipoprotein E genotype affect cardiovascular risk in subjects with acromegaly?

  2012cites this paper
• CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions

  2012cites this paper
• KIF6 719Arg Allele is Associated with Statin Effects on Cholesterol Levels in Amnestic Mild Cognitive Impairment and Alzheimer's Disease Patients

  2012cites this paper
• Human apolipoprotein E genotypes differentially modify house dust mite-induced airway disease in mice.

  2012cites this paper
• Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.

  2012cites this paper
• The apolipoprotein E polymorphism and cardiovascular diseases--an autopsy study.

  2012cites this paper
• Familial genetic risk factors in premature cardiovascular disease: a family study

  2012cites this paper
• Apolipoprotein E polymorphism is associated with both number of diseased vessels and extent of coronary artery disease in Czech patients with CAD.

  2012cites this paper
• Associations between Apolipoprotein E Genotype, Diet, Body Mass Index, and Serum Lipids in Lithuanian Adult Population

  2012cites this paper
• ApoE isoforms, treatment of diabetes and the risk of coronary heart disease.

  2012cites this paper
• The Apolipoprotein E (APOE) Gene Appears Functionally Monomorphic in Chimpanzees (Pan troglodytes)

  2012cites this paper
• Systematic Reviews and Meta- and Pooled Analyses Variations in Apolipoprotein E FrequencyWith Age in a Pooled Analysis of a Large Group of Older People

  2011cites this paper
• Thematic Review Series: Genetics of Human Lipid Diseases Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classifi cation and disease risk

  2011cites this paper
• Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people.

  2011cites this paper
• A functional mutation at position -155 in porcine APOE promoter affects gene expression

  2011cites this paper
• Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk

  2011cites this paper
• Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy

  2011cites this paper
• Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

  2011cites this paper
• Effect of Obesity, Serum Lipoproteins, and Apolipoprotein E Genotypes on Mortality in Hospitalized Elderly Patients

  2011cites this paper
• APOE polymorphism is associated with lipid profile, but not with arterial stiffness in the general population

  2010cites this paper
• Apolipoprotein E genotype and mortality in Southern European and Anglo-Celt patients with type 2 diabetes: the Fremantle Diabetes Study.

  2010cites this paper
• Apolipoprotein E Genotype and Cardiovascular Diseases in the Elderly

  2010cites this paper
• Apolipoprotein E Polymorphisms and Postprandial Triglyceridemia Before and After Fenofibrate Treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study

  2010cites this paper
• Genetic architecture of coronary artery disease in the genome-wide era: implications for the emerging "golden dozen" loci.

  2009cites this paper
• Genetic Architecture of Coronary Artery Disease in the Genome-Wide Era: Implications for the Emerging “Golden Dozen” Loci

  2009cites this paper