Isl1 and Ldb Co‐regulators of transcription are essential early determinants of mouse limb development

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Developmental Dynamics

• Publication date

  2012-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/dvdy.23761PMID 22411555PMCID PMC3443392
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice

  2011influential reference
• Site-specific recombinases for manipulation of the mouse genome.

  2009cited by this paper
• LIM homeobox transcription factors integrate signaling events that control three-dimensional limb patterning and growth

  2009cited by this paper
• Vertebrate limb bud development: moving towards integrative analysis of organogenesis

  2009cited by this paper
• LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum

  2007cited by this paper
• Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells.

  2007influential reference
• Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning

  2005cited by this paper
• Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development

  2005cited by this paper
• Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo

  2003cited by this paper
• Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation

  2003cited by this paper
• Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois

  2003cited by this paper
• Functions of FGF signalling from the apical ectodermal ridge in limb development

  2002influential reference
• Patterning mechanisms controlling vertebrate limb development.

  2001cited by this paper
• A highly efficient ligand‐regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

  2001cited by this paper
• Fgf8 signalling from the AER is essential for normal limb development

  2000cited by this paper
• Fgf8 is required for outgrowth and patterning of the limbs

  2000cited by this paper
• Fgf10 is essential for limb and lung formation

  1999influential reference
• Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless.

  1998influential reference
• The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor.

  1997influential reference
• Specification of the wing by localized expression of wingless protein

  1996cited by this paper
• Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb.

  1996cited by this paper
• Evidence of a role for T-☐ genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity

  1996cited by this paper
• Roles for FGF8 in the induction, initiation, and maintenance of chick limb development.

  1996cited by this paper
• Expression of the T‐box family genes, Tbx1–Tbx5, during early mouse development

  1996cited by this paper
• Hox genes and the evolution of vertebrate axial morphology.

  1995cited by this paper
• Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila.

  1993cited by this paper
• apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins.

  1992cited by this paper

• Shifts in embryonic oxygen levels cue heterochrony in limb initiation

  2024cites this paper
• Sall genes regulate hindlimb initiation in mouse embryos.

  2024cites this paper
• Generation of human expandable limb-bud-like progenitors via chemically induced dedifferentiation.

  2024cites this paper
• Functional genomics of human skeletal development and the patterning of height heritability.

  2024cites this paper
• Human ERG oncoprotein represses a Drosophila LIM domain binding protein–coding gene Chip

  2023cites this paper
• The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5

  2023cites this paper
• G9a inactivation in progenitor cells with Isl1-Cre with reduced recombinase activity models aspects of Dandy-Walker complex

  2023cites this paper
• Lateral thinking in syndromic congenital cardiovascular disease

  2023cites this paper
• Molecular Function and Contribution of TBX4 in Development and Disease.

  2022cites this paper
• Cell fate decisions, transcription factors and signaling during early retinal development

  2022cites this paper
• SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

  2022cites this paper
• A human embryonic limb cell atlas resolved in 1 space and time 2

  2022cites this paper
• LIM Homeodomain (LIM-HD) Genes and Their Co-Regulators in Developing Reproductive System and Disorders of Sex Development

  2021cites this paper
• Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects

  2021cites this paper
• Enhancer long-range contacts: The multi-adaptor protein LDB1 is the tie that binds.

  2019cites this paper
• LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus

  2019cites this paper
• Pigeon foot feathering reveals conserved limb identity networks

  2019cites this paper
• Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a

  2018cites this paper
• Genetics of clubfoot; recent progress and future perspectives.

  2017cites this paper
• Isl 1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp 4 , Fgf 10 and Wnt 5 a

  2017cites this paper
• Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.

  2017cites this paper
• The Role of LMO4 in the Regulation of SLK Localization & Activation within Migrating Cells and in Murine Mammary Tumorigenesis

  2016cites this paper
• The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis

  2016cites this paper
• Histone modifications interact with DNA methylation at the GATA4 promoter during differentiation of mesenchymal stem cells into cardiomyocyte‐like cells

  2016cites this paper
• Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4.

  2015cites this paper
• Expression and function of the LIM-homeodomain transcription factor Islet-1 in the developing and mature vertebrate retina.

  2015cites this paper
• How the embryo makes a limb: determination, polarity and identity

  2015cites this paper
• Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood

  2015cites this paper
• RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation

  2015cites this paper
• Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

  2014cites this paper
• Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway.

  2014cites this paper
• Expression of Isl1 during mouse development.

  2013cites this paper
• Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

  2013cites this paper
• Stem Cell Repor ts

  year unknowncites this paper