Reduction of the amplitude of preovulatory LH and FSH surges and of the amplitude of the in vitro GnRH-induced LH release by substance P. Reversal of the effect by RP 67580.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Neuropharmacology

• Publication date

  1996-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0028-3908(96)00124-4PMID 9076760
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bioactive peptides in anterior pituitary cells.

  1994cited by this paper
• Higher potency of RP 67580, in the mouse and the rat compared with other nonpeptide and peptide tachykinin NK1 antagonists

  1993cited by this paper
• Hypothalamo-anterior pituitary gonadotropin-releasing hormone and substance-P systems during the 17 beta-estradiol-induced plasma luteinizing hormone surge in the ovariectomized female monkey.

  1993cited by this paper
• Distribution of the substance P receptor (NK-1 receptor) in the central nervous system.

  1993cited by this paper
• Substance P (NK-1 receptor) antagonists: in vivo and in vitro activities in rats and guinea pigs.

  1993cited by this paper
• Substance P: multifunctional peptide in the hypothalamo-pituitary system?

  1992cited by this paper
• Substance P stimulates luteinizing hormone secretion from anterior pituitary cells in culture.

  1992cited by this paper
• Binding of an iodinated substance P analogue to cultured anterior pituitary prolactin- and luteinizing hormone-containing cells.

  1992cited by this paper
• In-vivo inhibition of the preovulatory LH surge by substance P and in-vitro modulation of gonadotrophin-releasing hormone-induced LH release by substance P, oestradiol and progesterone in the female rat.

  1991cited by this paper
• Ovulation induction with pulsatile gonadotropin-releasing hormone: technical modalities and clinical perspectives.

  1991cited by this paper
• Pharmacological properties of a potent and selective nonpeptide substance P antagonist.

  1991cited by this paper
• Gonadal steroid regulation of substance P (SP) and SP-encoding messenger ribonucleic acids in the rat anterior pituitary and hypothalamus.

  1990cited by this paper
• Stimulatory role of substance P on gonadotropin release in ovariectomized rats.

  1990cited by this paper
• The regulation of neuropeptide expression in rat anterior pituitary following chronic manipulation of estrogen status: a comparison between substance P, neuropeptide Y, neurotensin, and vasoactive intestinal peptide.

  1990cited by this paper
• Binding of a iodinated substance P analog to a NK-1 receptor on isolated cell membranes from rat anterior pituitary.

  1989cited by this paper
• Pharmacological receptors for substance P and neurokinins.

  1987cited by this paper
• Substance P stimulates gonadotropin-releasing hormone release from rat hypothalamus in vitro with involvement of oestrogen.

  1987cited by this paper
• Binding studies of substance P anterior pituitary binding sites: changes in substance P binding sites during the rat estrous cycle.

  1985cited by this paper
• Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices.

  1985cited by this paper
• The effects of gonadal steroids on the content of substance P in the rat anterior pituitary.

  1984cited by this paper
• Substance P.

  1983cited by this paper
• In vivo and in vitro effects of substance P and neurotensin on gonadotropin and prolactin release.

  1979cited by this paper
• [Stimulation of pituitary LH and FSH secretion after immunoneutralization of endogenous substance P in the cycling rat].

  1978cited by this paper
• [Inhibition of LH-RH induced release of gonadotropins by substance P in cultured rat anterior pituitary cells].

  1978cited by this paper
• Delayed effects of in vivo LHRH immunoneutralization on gonadotropins and prolactin secretion in the female rat.

  1976cited by this paper
• [Demonstration of a radioimmunologic determination of rat luteinizing hormone (LH) by means of a sheep anti-LH immune serum and a labelled rat LH preparation].

  1969cited by this paper

• Sexual Dimorphic Distribution of Hypothalamic Tachykinin1 Cells and Their Innervations to GnRH Neurons in the Zebrafish

  2021cites this paper
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  2006cites this paper
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  2002cites this paper
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  2002cites this paper
• Substance P Downregulates Basal and Gonadotropin‐Releasing Hormone‐Induced Gonadotropin In Vitro Secretion by Pituitary Gland of Crested Newt, Triturus carnifex

  2000cites this paper
• In vitro basal and GnRH-stimulated secretion of gonadotrophins reflects long-lasting modulatory effects, and peripheral levels are not predicted by pituitary responsiveness to GnRH.

  1999cites this paper
• Modulation of gonadotropin levels by peptides acting at the anterior pituitary gland.

  1999cites this paper
• Ovarian Steroid Modulation of Neurokinin Contents in Hypothalamus, Pituitary, Trigeminal Nucleus, and Cervical Spinal Cord of the Ovariectomized Female Rat

  1998cites this paper
• The in vitro effect of substance P on the GnRH-induced LH release depends on the steroidal environment and is reverted by a NK1 receptor antagonist (RP 67580) in the cycling female rat.

  1998cites this paper