Antagonism of activin by inhibin and inhibin receptors: a functional role for betaglycan.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular and Cellular Endocrinology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11911962
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antagonism of activin by inhibin and inhibin receptors: a functional role for betaglycan-glycan.

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• Structure and expression of a membrane component of the inhibin receptor system.

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• Activins and their receptors in female reproduction.

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• The Smad pathway.

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• Activin signal transduction pathways.

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• Betaglycan binds inhibin and can mediate functional antagonism of activin signalling

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• Identification of a Binding Site on the Type II Activin Receptor for Activin and Inhibin*

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• Role of activins in the male reproductive tract.

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• Role of activin and other peptide growth factors in body patterning in the early amphibian embryo.

  1999cited by this paper
• Identification of high affinity binding sites for inhibin on ovine pituitary cells in culture.

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• Roles of pathway-specific and inhibitory Smads in activin receptor signaling.

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• A novel role of activin in inflammation and repair.

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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Smad7 Is an Activin-inducible Inhibitor of Activin-induced Growth Arrest and Apoptosis in Mouse B Cells*

  1998cited by this paper
• Identification of an Inhibin Receptor in Gonadal Tumors from Inhibin α-Subunit Knockout Mice*

  1998cited by this paper
• Activins and Activin Receptors in Cell Growth 1

  1997cited by this paper
• Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells.

  1997cited by this paper
• Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.

  1997cited by this paper
• Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation

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• Activation of signalling by the activin receptor complex

  1996cited by this paper
• Pituitary follistatin and inhibin subunit messenger ribonucleic acid levels are differentially regulated by local and hormonal factors.

  1996cited by this paper
• Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development.

  1996cited by this paper
• Hybridization histochemical and immunohistochemical localization of inhibin/activin subunits and messenger ribonucleic acids in the rat brain

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• Inhibin Antagonizes Inhibition of Liver Cell Growth by Activin by a Dominant-negative Mechanism (*)

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• Activins and the receptor serine kinase superfamily.

  1995cited by this paper
• Expression of Transforming Growth Factor Type III Receptor in Vascular Endothelial Cells Increases Their Responsiveness to Transforming Growth Factor β2 (*)

  1995cited by this paper
• Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

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• Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding.

  1994cited by this paper
• Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

  1994cited by this paper
• Gonadotropin-releasing hormone pulse frequency regulates expression of pituitary follistatin messenger ribonucleic acid: a mechanism for differential gonadotrope function.

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• Amino acid determinants that drive heparan sulfate assembly in a proteoglycan.

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• Effect of local injection of activin A on bone formation in newborn rats.

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  1993cited by this paper
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  1993cited by this paper
• Betaglycan presents ligand to the TGF beta signaling receptor.

  1993cited by this paper
• The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand.

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• Bovine bone activin enhances bone morphogenetic protein-induced ectopic bone formation.

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• Cloning of a second type of activin receptor and functional characterization in Xenopus embryos.

  1992cited by this paper
• Isoform-specific transforming growth factor-beta binding proteins with membrane attachments sensitive to phosphatidylinositol-specific phospholipase C.

  1991cited by this paper
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  1991cited by this paper
• Expression cloning and characterization of the TGF-beta type III receptor.

  1991cited by this paper
• Central activin administration modulates corticotropin-releasing hormone and adrenocorticotropin secretion.

  1991cited by this paper
• Activin-A inhibits proopiomelanocortin messenger RNA accumulation and adrenocorticotropin secretion of AtT20 cells.

  1991cited by this paper
• Activin-A modulates gonadotropin-releasing hormone secretion from a gonadotropin-releasing hormone-secreting neuronal cell line.

  1991cited by this paper
• Expression cloning of an activin receptor, a predicted transmembrane serine kinase.

  1991cited by this paper
• Evidence for an autocrine role of activin B within rat anterior pituitary cultures.

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• Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

  1990cited by this paper
• Activin-binding protein from rat ovary is follistatin.

  1990cited by this paper
• The transforming growth factor-beta family.

  1990cited by this paper
• Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro.

  1990cited by this paper
• Activin is a nerve cell survival molecule

  1990cited by this paper
• Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms.

  1990cited by this paper
• Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.

  1990cited by this paper
• Transforming growth factor-beta (TGF-beta) receptor proteoglycan. Cell surface expression and ligand binding in the absence of glycosaminoglycan chains.

  1989cited by this paper
• Production and regulation of inhibin subunits in pituitary gonadotropes.

  1989cited by this paper
• Binding of transforming growth factor-beta to cell surface proteins varies with cell type.

  1989cited by this paper
• Pituitary follicular cells secrete both vascular endothelial growth factor and follistatin.

  1989cited by this paper
• The high molecular weight receptor to transforming growth factor-beta contains glycosaminoglycan chains.

  1988cited by this paper
• Inhibin β in central neural pathways involved in the control of oxytocin secretion

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• The transforming growth factor-beta receptor type III is a membrane proteoglycan. Domain structure of the receptor.

  1988cited by this paper
• Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin.

  1988cited by this paper
• Activin-A: a modulator of multiple types of anterior pituitary cells.

  1988cited by this paper
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• Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1.

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• Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

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• Inhibin A-subunit cDNAs from porcine ovary and human placenta.

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  1986cited by this paper
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  1986cited by this paper
• Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid.

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• Isolation of porcine follicular fluid inhibin of 32K daltons.

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• Isolation of inhibin from bovine follicular fluid.

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• Purification and partial characterization of inhibin from porcine follicular fluid.

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• Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

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