Activation, exposure and penetration of virally encoded, membrane-active polypeptides during non-enveloped virus entry.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Current protein and peptide science

• Publication date

  2008-01-31

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.2174/138920308783565732PMID 18336320
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The multipartite system that mediates entry of herpes simplex virus into the cell

  2007cited by this paper
• Mutational Evidence of Internal Fusion Loops in Herpes Simplex Virus Glycoprotein B

  2007cited by this paper
• Understanding HSV‐1 entry glycoproteins

  2007cited by this paper
• Structure of a Membrane-binding Domain from a Non-enveloped Animal Virus

  2006cited by this paper
• Fusion Peptide of Influenza Hemagglutinin Requires a Fixed Angle Boomerang Structure for Activity*

  2006cited by this paper
• Morphological Changes in the T=3 Capsid of Flock House Virus during Cell Entry

  2006cited by this paper
• Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane

  2006cited by this paper
• Class II virus membrane fusion proteins.

  2006cited by this paper
• Low pH-Dependent Endosomal Processing of the Incoming Parvovirus Minute Virus of Mice Virion Leads to Externalization of the VP1 N-Terminal Sequence (N-VP1), N-VP2 Cleavage, and Uncoating of the Full-Length Genome

  2006cited by this paper
• Conformational Changes in the VP1-Unique Region of Native Human Parvovirus B19 Lead to Exposure of Internal Sequences That Play a Role in Virus Neutralization and Infectivity

  2006cited by this paper
• Crystal Structure of Glycoprotein B from Herpes Simplex Virus 1

  2006cited by this paper
• Molecular gymnastics at the herpesvirus surface

  2006cited by this paper
• Membrane Structures of the Hemifusion-Inducing Fusion Peptide Mutant G1S and theFusion-Blocking Mutant G1V of Influenza Virus HemagglutininSuggest a Mechanism for Pore Opening in MembraneFusion

  2005cited by this paper
• Adenovirus Protein VI Mediates Membrane Disruption following Capsid Disassembly

  2005cited by this paper
• Properties and structures of the influenza and HIV fusion peptides on lipid membranes: implications for a role in fusion.

  2005cited by this paper
• The Structure of the Poliovirus 135S Cell Entry Intermediate at 10-Angstrom Resolution Reveals the Location of an Externalized Polypeptide That Binds to Membranes

  2005cited by this paper
• Putative autocleavage of reovirus mu1 protein in concert with outer-capsid disassembly and activation for membrane permeabilization.

  2005cited by this paper
• Identification and Characterization of the Putative Fusion Peptide of the Severe Acute Respiratory Syndrome-Associated Coronavirus Spike Protein

  2005cited by this paper
• Viral entry.

  2005cited by this paper
• The Ectodomain of Herpes Simplex Virus Glycoprotein H Contains a Membrane α-Helix with Attributes of an Internal Fusion Peptide, Positionally Conserved in the Herpesviridae Family

  2005cited by this paper
• Structural rearrangements in the membrane penetration protein of a non-enveloped virus

  2004cited by this paper
• Virus yoga: the role of flexibility in virus host cell recognition.

  2004cited by this paper
• Structure of the dengue virus envelope protein after membrane fusion

  2004cited by this paper
• Multistep Regulation of Membrane Insertion of the Fusion Peptide of Semliki Forest Virus

  2004cited by this paper
• Putative Autocleavage of Outer Capsid Protein μ1, Allowing Release of Myristoylated Peptide μ1N during Particle Uncoating, Is Critical for Cell Entry by Reovirus

  2004cited by this paper
• Poliovirus binding to its receptor in lipid bilayers results in particle-specific, temperature-sensitive channels.

  2004cited by this paper
• Genome Delivery and Ion Channel Properties Are Altered in VP4 Mutants of Poliovirus

  2003cited by this paper
• The HIV Env-mediated fusion reaction.

  2003cited by this paper
• Large-Scale, pH-Dependent, Quaternary Structure Changes in an RNA Virus Capsid Are Reversible in the Absence of Subunit Autoproteolysis

  2002cited by this paper
• Thermostability of Reovirus Disassembly Intermediates (ISVPs) Correlates with Genetic, Biochemical, and Thermodynamic Properties of Major Surface Protein μ1

  2002cited by this paper
• Strategy for Nonenveloped Virus Entry: a Hydrophobic Conformer of the Reovirus Membrane Penetration Protein μ1 Mediates Membrane Disruption

  2002cited by this paper
• Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3.

  2002cited by this paper
• Poliovirus cell entry: common structural themes in viral cell entry pathways.

  2002cited by this paper
• The VP1 Unique Region of Parvovirus B19 and Its Constituent Phospholipase A2-Like Activity

  2002cited by this paper
• Cytoplasmic Trafficking of Minute Virus of Mice: Low-pH Requirement, Routing to Late Endosomes, and Proteasome Interaction

  2002cited by this paper
• Cathepsin L and Cathepsin B Mediate Reovirus Disassembly in Murine Fibroblast Cells*

  2002cited by this paper
• Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin

  2001cited by this paper
• Trypsin Cleavage Stabilizes the Rotavirus VP4 Spike

  2001cited by this paper
• The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH.

  2001cited by this paper
• Localization of membrane permeabilization and receptor binding sites on the VP4 hemagglutinin of rotavirus: implications for cell entry.

  2001cited by this paper
• Junction adhesion molecule is a receptor for reovirus.

  2001cited by this paper
• Kinetic Analysis of the Effect of Poliovirus Receptor on Viral Uncoating: the Receptor as a Catalyst

  2001cited by this paper
• Molecular Tectonic Model of Virus Structural Transitions: the Putative Cell Entry States of Poliovirus

  2000cited by this paper
• Virus Maturation Targets the Protein Capsid to Concerted Disassembly and Unfolding*

  2000cited by this paper
• Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.

  2000cited by this paper
• Stabilization of poliovirus by capsid-binding antiviral drugs is due to entropic effects.

  2000cited by this paper
• Membrane partitioning of the cleavage peptide in flock house virus.

  2000cited by this paper
• Is the 135S Poliovirus Particle an Intermediate during Cell Entry?

  2000cited by this paper
• Selective Membrane Permeabilization by the Rotavirus VP5* Protein Is Abrogated by Mutations in an Internal Hydrophobic Domain

  2000cited by this paper
• Poliovirus Mutants at Histidine 195 of VP2 Do Not Cleave VP0 into VP2 and VP4

  1999cited by this paper
• In Vitro Recoating of Reovirus Cores with Baculovirus-Expressed Outer-Capsid Proteins μ1 and ς3

  1999cited by this paper
• Reovirus Virion-Like Particles Obtained by Recoating Infectious Subvirion Particles with Baculovirus-Expressed s3 Protein: an Approach for Analyzing s3 Functions during Virus Entry

  1999cited by this paper
• Controlled conformational transitions in the MVM virion expose the VP1 N-terminus and viral genome without particle disassembly.

  1999cited by this paper
• A highly membrane-active peptide in Flock House virus: implications for the mechanism of nodavirus infection.

  1999cited by this paper
• Membrane interactions of the synthetic N-terminal peptide of HIV-1 gp41 and its structural analogs.

  1999cited by this paper
• Mutational Analysis of the Putative Fusion Domain of Ebola Virus Glycoprotein

  1999cited by this paper
• Rotavirus Capsid Protein VP5* Permeabilizes Membranes

  1999cited by this paper
• An animal virus-derived peptide switches membrane morphology: possible relevance to nodaviral transfection processes.

  1999cited by this paper
• Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.

  1998cited by this paper
• Interaction of Poliovirus with Its Purified Receptor and Conformational Alteration in the Virion

  1998cited by this paper
• The Coxsackievirus-Adenovirus Receptor Protein Can Function as a Cellular Attachment Protein for Adenovirus Serotypes from Subgroups A, C, D, E, and F

  1998cited by this paper
• Evidence of Viral Capsid Dynamics Using Limited Proteolysis and Mass Spectrometry*

  1998cited by this paper
• Characterization of the ion channels formed by poliovirus in planar lipid membranes

  1997cited by this paper
• The amino-terminal fusion domain peptide of human immunodeficiency virus type 1 gp41 inserts into the sodium dodecyl sulfate micelle primarily as a helix with a conserved glycine at the micelle-water interface

  1997cited by this paper
• The poliovirus 135S particle is infectious

  1996cited by this paper
• The role of the adenovirus protease on virus entry into cells.

  1996cited by this paper
• Trypsin activation pathway of rotavirus infectivity

  1996cited by this paper
• Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells

  1996cited by this paper
• The 2.8 A structure of a T = 4 animal virus and its implications for membrane translocation of RNA.

  1996cited by this paper
• Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: Structure of the empty capsid assembly intermediate at 2.9 Å resolution

  1994cited by this paper
• Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature

  1994cited by this paper
• Functional implications of quasi-equivalence in a T = 3 icosahedral animal virus established by cryo-electron microscopy and X-ray crystallography.

  1994cited by this paper
• Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue.

  1994cited by this paper
• Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction

  1993cited by this paper
• A mutation in VP4 defines a new step in the late stages of cell entry by poliovirus

  1993cited by this paper
• Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment.

  1993cited by this paper
• Difference imaging of adenovirus: bridging the resolution gap between X‐ray crystallography and electron microscopy.

  1993cited by this paper
• Ordered duplex RNA controls capsid architecture in an icosahedral animal virus

  1993cited by this paper
• Stepwise dismantling of adenovirus 2 during entry into cells.

  1993cited by this paper
• Use of recombinant baculoviruses in synthesis of morphologically distinct viruslike particles of flock house virus, a nodavirus

  1993cited by this paper
• Ion channels induced in lipid bilayers by subvirion particles of the nonenveloped mammalian reoviruses.

  1993cited by this paper
• Maturation cleavage required for infectivity of a nodavirus

  1992cited by this paper
• Interaction of rotavirus particles with liposomes

  1992cited by this paper
• Mammalian reoviruses contain a myristoylated structural protein

  1991cited by this paper
• Mutagenesis of the putative fusion domain of the Semliki Forest virus spike protein

  1991cited by this paper
• Influence of different ionic and pH environments on structural alterations of poliovirus and their possible relation to virus uncoating.

  1991cited by this paper
• Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding

  1990cited by this paper
• Lack of myristoylation of poliovirus capsid polypeptide VP0 prevents the formation of virions or results in the assembly of noninfectious virus particles

  1990cited by this paper
• Role of myristoylation of poliovirus capsid protein VP4 as determined by site‐directed mutagenesis of its N‐terminal sequence.

  1989cited by this paper
• Myristylation of picornavirus capsid protein VP4 and its structural significance

  1987cited by this paper
• Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle

  1987cited by this paper
• Three-dimensional structure of poliovirus at 2.9 A resolution.

  1985cited by this paper
• Proteolytic enhancement of rotavirus infectivity: molecular mechanisms

  1981cited by this paper

• Structural determinants of rotavirus proteolytic activation

  2025cites this paper
• Structural determinants of rotavirus proteolytic activation

  2025cites this paper
• Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses

  2025cites this paper
• Non-equilibrium Virus Particle Dynamics: Microsecond MD Simulations of the Complete Flock House Virus Capsid Under Different Conditions.

  2023cites this paper
• Nanodiscs: Game changer nano-therapeutics and structural biology tools

  2023cites this paper
• Human astrovirus capsid protein releases a membrane lytic peptide upon trypsin maturation

  2023cites this paper
• Structure and energetics guide dynamic behaviour in a T = 3 icosahedral virus capsid.

  2023cites this paper
• Dynamics and stability in the maturation of a eukaryotic virus: a paradigm for chemically programmed large-scale macromolecular reorganization

  2021cites this paper
• Atomistic dynamics of a viral infection process: Release of membrane lytic peptides from a non-enveloped virus

  2021cites this paper
• Real-Time Imaging of Polioviral RNA Translocation across a Membrane

  2021cites this paper
• Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis

  2021cites this paper
• Cell-penetrating peptides in the intracellular delivery of viral nanoparticles.

  2021cites this paper
• Plant-expressed virus-like particles reveal the intricate maturation process of a eukaryotic virus

  2021cites this paper
• Large nanodiscs going viral.

  2020cites this paper
• Large Nanodiscs: A Potential Game Changer in Structural Biology of Membrane Protein Complexes and Virus Entry

  2020cites this paper
• Hydrophobicity and oligomerization are essential parameters for membrane penetration activity of the VP4 peptide from Hepatitis A Virus (HAV).

  2019cites this paper
• Structural Dynamics of Nonenveloped Virus Disassembly Intermediates

  2019cites this paper
• The Arginines in the N-Terminus of the Porcine Circovirus 2 Virus-like Particles Are Responsible for Disrupting the Membranes at Neutral and Acidic pH.

  2019cites this paper
• Folding a viral peptide in different membrane environments: pathway and sampling analyses

  2018cites this paper
• Membranotropic peptides mediating viral entry

  2018cites this paper
• Membrane Penetration by Bacterial Viruses

  2017cites this paper
• Enzymes and Enzyme Activity Encoded by Nonenveloped Viruses.

  2017cites this paper
• Influence of membrane composition on the binding and folding of a membrane lytic peptide from the non-enveloped flock house virus.

  2017cites this paper
• Breach: Host Membrane Penetration and Entry by Nonenveloped Viruses.

  2017cites this paper
• Non-Enveloped Virus Entry: Structural Determinants and Mechanism of Functioning of a Viral Lytic Peptide.

  2016cites this paper
• Viral entry pathways: the example of common cold viruses

  2016cites this paper
• Development and application of monoclonal antibodies for detection and analysis of aquareoviruses

  2016cites this paper
• Virus particle dynamics derived from CryoEM studies.

  2016cites this paper
• Getting across the cell membrane: an overview for small molecules, peptides, and proteins.

  2015cites this paper
• The C-terminal region of the non-structural protein 2B from Hepatitis A Virus demonstrates lipid-specific viroporin-like activity

  2015cites this paper
• Data to knowledge: how to get meaning from your result

  2015cites this paper
• Characterisation of Structural Proteins from Chronic Bee Paralysis Virus (CBPV) Using Mass Spectrometry

  2015cites this paper
• Membranotropic Cell Penetrating Peptides: The Outstanding Journey

  2015cites this paper
• Engineering Virus Capsids Into Biomedical Delivery Vehicles: Structural Engineering Problems in Nanoscale.

  2015cites this paper
• Triatoma Virus Recombinant VP4 Protein Induces Membrane Permeability through Dynamic Pores

  2015cites this paper
• Exploitation of viral properties for intracellular delivery‡

  2014cites this paper
• Nonenveloped capsid: mechanisms of viral entry

  2014cites this paper
• The VP4 Peptide of Hepatitis A Virus Ruptures Membranes through Formation of Discrete Pores

  2014cites this paper
• The VP 4 peptide of Hepatitis A Virus ( HAV ) Ruptures Membranes 2 Through Formation of Discrete Pores

  2014cites this paper
• Host Molecular Chaperones: Cell Surface Receptors for Viruses

  2013cites this paper
• Characterization of Human Astrovirus Cell Entry

  2013cites this paper
• Moonlighting Cell Stress Proteins in Microbial Infections

  2013cites this paper
• Confessions of an icosahedral virus crystallographer.

  2013cites this paper
• Investigating directionality of genome release from human rhinovirus A 2

  2013cites this paper
• Identification of viral proteins and cellular pathways involved in the induction of apoptosis of African horse sickness virus-infected mammalian cells

  2012cites this paper
• Dissecting Quasi-Equivalence in Nonenveloped Viruses: Membrane Disruption Is Promoted by Lytic Peptides Released from Subunit Pentamers, Not Hexamers

  2012cites this paper
• Functional characterization of the African horse sickness virus VP5 protein, and studies regarding virus-induced apoptosis in cultured mammalian cells

  2012cites this paper
• Le virus de la paralysie chronique de l'abeille : contribution à l'étude de la caractérisation de protéines virales

  2012cites this paper
• Host RNAs, including transposons, are encapsidated by a eukaryotic single-stranded RNA virus

  2012cites this paper
• Virus maturation.

  2012cites this paper
• Enter the kill zone: Initiation of death signaling during virus entry

  2011cites this paper
• Membrane permeabilization of the African horse sickness virus VP5 protein is mediated by two N-terminal amphipathic α-helices

  2011cites this paper
• Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

  2011cites this paper
• Virion glycosylation governs integrity and infectivity of infectious pancreatic necrosis virus

  2011cites this paper
• Liposomal Nanocontainers as Models for Viral Infection: Monitoring Viral Genomic RNA Transfer through Lipid Membranes

  2011cites this paper
• Human Adenovirus Analyses of Membrane Disruption by Functional Genetic and Biophysical

  2011cites this paper
• Class II enveloped viruses

  2011cites this paper
• Determinants of Strain-Specific Differences in Efficiency of Reovirus Entry

  2010cites this paper
• Study of Andes virus entry and neutralization using a pseudovirion system.

  2010cites this paper
• Determinants of Strain-Specific Differences in Efficiency of Reovirus Entry (cid:1)

  2010cites this paper
• Structure and Function of a Genetically Engineered Mimic of a Nonenveloped Virus Entry Intermediate

  2010cites this paper
• 3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.

  2010cites this paper
• Liposomal leakage induced by virus-derived peptides, viral proteins, and entire virions: rapid analysis by chip electrophoresis.

  2010cites this paper
• Subunits fold at position-dependent rates during maturation of a eukaryotic RNA virus

  2010cites this paper
• Uncoating of human rhinoviruses

  2010cites this paper
• Flock house virus: a model system for understanding non-enveloped virus entry and membrane penetration.

  2010cites this paper
• Virus entry paradigms

  2009cites this paper
• Dissecting the Functional Domains of a Nonenveloped Virus Membrane Penetration Peptide

  2009cites this paper
• Low Endocytic pH and Capsid Protein Autocleavage Are Critical Components of Flock House Virus Cell Entry

  2009cites this paper
• Molecular dissection of flavivirus membrane fusion by structure-based mutational analysis

  2009cites this paper
• Multi-disciplinary studies of viruses: the role of structure in shaping the questions and answers.

  2008cites this paper
• Rescue of Maturation-Defective Flock House Virus Infectivity with Noninfectious, Mature, Viruslike Particles

  2007cites this paper