Combination therapy in mice: what can we learn that may be useful for understanding rheumatoid arthritis?

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Springer Seminars in Immunopathology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00832005PMID 9836375
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.

  1998cited by this paper
• CD40 and its ligand in cell-mediated immunity.

  1998cited by this paper
• CD40 and its ligand in cell-mediated immunity.

  1998cited by this paper
• Blockade of IL‐12 during the induction of collagen‐induced arthritis (CIA) markedly attenuates the severity of the arthritis

  1998cited by this paper
• Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans.

  1997cited by this paper
• Treatment of a newly established transgenic model of chronic arthritis with nondepleting anti-CD4 monoclonal antibody.

  1997cited by this paper
• Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram.

  1997cited by this paper
• The Dunlop-Dottridge Lecture: prognosis in inflammatory arthritis: the value of HLA genotyping and the oncological analogy.

  1997cited by this paper
• Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways.

  1997cited by this paper
• Biologic agents for treating rheumatoid arthritis. Concepts and progress.

  1997cited by this paper
• Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen‐induced arthritis

  1997cited by this paper
• Gp130 and the interleukin-6 family of cytokines.

  1997cited by this paper
• Suppression of collagen-induced arthritis by continuous administration of IL-4.

  1997cited by this paper
• Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction.

  1997cited by this paper
• Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

  1996cited by this paper
• The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells

  1996cited by this paper
• Cyclosporine, FK-506, rapamycin, and other immunomodulators.

  1996cited by this paper
• Effect of IL-10 on collagen-induced arthritis in mice

  1996cited by this paper
• Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen‐induced arthritis

  1996cited by this paper
• Interleukin-10 inhibition of the progression of established collagen-induced arthritis.

  1996cited by this paper
• Prevention and amelioration of collagen‐induced arthritis by blockade of the CD28 co‐stimulatory pathway: requirement for both B7‐1 and B7‐2

  1996cited by this paper
• Interleukin‐10 Suppresses the Development of Collagen Type II‐Induced Arthritis and Ameliorates Sustained Arthritis in Rats

  1996cited by this paper
• Suppression of collagen-induced arthritis by an angiogenesis inhibitor, AGM-1470, in combination with cyclosporin: reduction of vascular endothelial growth factor (VEGF).

  1995cited by this paper
• Monoclonal anti‐TNFα Antibody as a Probe of Pathogenesis and Therapy of Rheumatoid Disease

  1995cited by this paper
• Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

  1995cited by this paper
• Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.

  1995cited by this paper
• Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4.

  1995cited by this paper
• The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

  1995cited by this paper
• Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis.

  1995cited by this paper
• Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis.

  1994cited by this paper
• Interleukin 6 promotes murine lupus in NZB/NZW F1 mice.

  1994cited by this paper
• Treatment of murine lupus with CTLA4Ig.

  1994cited by this paper
• Exacerbation of established collagen-induced arthritis in mice treated with an anti-T cell receptor antibody.

  1994cited by this paper
• Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis

  1994cited by this paper
• Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.

  1994cited by this paper
• Effects of early and late treatment with anti-CD4 monoclonal antibody on autoimmune disease in MRL/MP-lpr/lpr mice.

  1994cited by this paper
• Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis

  1994cited by this paper
• Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis.

  1994cited by this paper
• Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.

  1993cited by this paper
• Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

  1993cited by this paper
• The Mechanism of Action of FK‐506 and Cyclosporin A

  1993cited by this paper
• Depletion of alpha/beta T cells by a monoclonal antibody against the alpha/beta T cell receptor suppresses established adjuvant arthritis, but not established collagen-induced arthritis in rats

  1992cited by this paper
• FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

  1992cited by this paper
• Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

  1992cited by this paper
• Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.

  1992cited by this paper
• Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice.

  1992cited by this paper
• The Influence of HLA-DRB1 Genes on Disease Severity in Rheumatoid Arthritis

  1992cited by this paper
• Anti‐T cell receptor antibody treatment of rats with established autologous collagen‐induced arthritis: suppression of arthritis without reduction of anti‐type II collagen autoantibody levels

  1991cited by this paper
• Monoclonal antibodies in diagnosis and therapy

  1991cited by this paper
• Suppression of collagen-induced arthritis by combination cyclosporin A and methotrexate therapy.

  1991influential reference
• Treatment of collagen-induced arthritis in rats with a monoclonal antibody against the alpha/beta T cell antigen receptor.

  1991cited by this paper
• Cyclosporin a modulation of tumor necrosis factor gene expression and effects in vitro and in vivo.

  1990cited by this paper
• How important are T cells in chronic rheumatoid synovitis?

  1990cited by this paper
• Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.

  1989cited by this paper
• Collagen induced arthritis as an experimental model for rheumatoid arthritis

  1989cited by this paper
• Rheumatoid arthritis complicated by infection with the human immunodeficiency virus and the development of Sjögren's syndrome.

  1989cited by this paper
• Experimental autoimmune arthritis in mice. II. Early events in the elicitation of the autoimmune phenomenon induced by homologous type II collagen.

  1988cited by this paper
• Immunosuppression of collagen-induced arthritis in mice with an anti-IL-2 receptor antibody.

  1988cited by this paper
• The progression of the inflammation in established collagen‐induced arthritis can be altered by treatments with immunological or pharmacological agents which inhibit T cell activities

  1988cited by this paper
• Nature of the type II collagen autoimmunity in mice susceptible to collagen-induced arthritis.

  1988cited by this paper
• Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma.

  1988cited by this paper
• The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis.

  1987cited by this paper
• Experimental autoimmune arthritis in mice. I. Homologous type II collagen is responsible for self-perpetuating chronic polyarthritis.

  1987cited by this paper
• CD4 monoclonal antibody pairs for immunosuppression and tolerance induction

  1987influential reference
• Homologous type II collagen induces chronic and progressive arthritis in mice.

  1986cited by this paper
• Treatment of Autoimmune Disease with Total Lymphoid Irradiation Cellular and Humoral Mechanisms

  1986cited by this paper
• Induction of tolerance by monoclonal antibody therapy

  1986cited by this paper
• Type II collagen-induced arthritis in mice. III. Suppression of arthritis by using monoclonal and polyclonal anti-Ia antisera.

  1985cited by this paper
• Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4

  1985cited by this paper
• Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

  1984cited by this paper
• Effect of antithymocyte serum on collagen arthritis in rats: evidence that T cells are involved in its pathogenesis.

  1984cited by this paper
• Type II collagen-induced arthritis in mice. II. Passive transfer and suppression by intravenous injection of anti-type II collagen antibody or free native type II collagen.

  1984cited by this paper
• Collagen arthritis as a relevant model for rheumatoid arthritis.

  1982cited by this paper
• Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritis.

  1981cited by this paper
• Immunisation against heterologous type II collagen induces arthritis in mice

  1980cited by this paper
• Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG

  1979influential reference
• Lymphocyte involvement in rheumatoid arthritis. Studies during thoracic duct drainage.

  1977cited by this paper
• Autoimmunity to type II collagen an experimental model of arthritis

  1977cited by this paper
• Lymphocyte Involvement in Rheumatoid Arthritis

  1977cited by this paper
• Predominantly T-cell infiltrate in rheumatoid synovial membranes.

  1975cited by this paper
• Materials and Methods Brief Definitive Report Induction of Arthritis in Monkeys by Immunization with Type Ii Collagen

  year unknowncited by this paper

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  2014cites this paper
• Regulatory aspects of evaluating combination treatments in autoimmune diseases

  2009cites this paper
• Immunotherapy for rheumatoid arthritis.

  2001cites this paper
• Tumour necrosis factor‐alpha (TNF‐α) enhances lymphocyte migration into rheumatoid synovial tissue transplanted into severe combined immunodeficient (SCID) mice

  2000cites this paper