Suzuki–Miyaura cross-coupling reaction of aryl and heteroaryl pinacol boronates for the synthesis of 2-substituted pyrimidines

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Tetrahedron

• Publication date

  2012-01-07

• Fields of study

  Chemistry

• Identifiers
  DOI 10.1016/J.TET.2011.10.057
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2.

  2011cited by this paper
• Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.

  2011cited by this paper
• General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates.

  2010cited by this paper
• Practical Aspects of Carbon—Carbon Cross-Coupling Reactions Using Heteroarenes

  2010cited by this paper
• A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids.

  2010cited by this paper
• Discovery of CYT997: a structurally novel orally active microtubule targeting agent.

  2009cited by this paper
• Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors.

  2009cited by this paper
• Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

  2009cited by this paper
• Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation.

  2009cited by this paper
• A general solution for unstable boronic acids: slow-release cross-coupling from air-stable MIDA boronates.

  2009cited by this paper
• Scope of the Suzuki-Miyaura cross-coupling reactions of potassium heteroaryltrifluoroborates.

  2009cited by this paper
• Divergent solution-phase synthesis of diarylpyrimidine libraries as selective A3 adenosine receptor antagonists.

  2009cited by this paper
• Efficient Suzuki-Miyaura coupling of (hetero)aryl chlorides with thiophene- and furanboronic acids in aqueous n-butanol.

  2008cited by this paper
• Highly efficient Suzuki-Miyaura coupling of heterocyclic substrates through rational reaction design.

  2008cited by this paper
• An efficient synthesis and substitution of 3-aroyl-2-bromobenzo[b]furans.

  2008cited by this paper
• Cyclic triolborates: air- and water-stable ate complexes of organoboronic acids.

  2008cited by this paper
• Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand.

  2007cited by this paper
• Highly efficient monophosphine-based catalyst for the palladium-catalyzed suzuki-miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters.

  2007cited by this paper
• Simple palladium(II) precatalyst for Suzuki-Miyaura couplings: efficient reactions of benzylic, aryl, heteroaryl, and vinyl coupling partners.

  2007cited by this paper
• 9-fluorenylphosphines for the Pd-catalyzed sonogashira, suzuki, and Buchwald-Hartwig coupling reactions in organic solvents and water.

  2007cited by this paper
• Organotrifluoroborates: protected boronic acids that expand the versatility of the Suzuki coupling reaction.

  2007cited by this paper
• A simple and modular strategy for small molecule synthesis: iterative Suzuki-Miyaura coupling of B-protected haloboronic acid building blocks.

  2007cited by this paper
• New catalysts for Suzuki-Miyaura coupling reactions of heteroatom-substituted heteroaryl chlorides.

  2007cited by this paper
• Synthetic method for multifunctionalized oligoarenes using pinacol esters of hydroxyphenylboronic acids.

  2006cited by this paper
• Modified (NHC)Pd(allyl)Cl (NHC = N-heterocyclic carbene) complexes for room-temperature Suzuki-Miyaura and Buchwald-Hartwig reactions.

  2006cited by this paper
• New air-stable catalysts for general and efficient suzuki-miyaura cross-coupling reactions of heteroaryl chlorides.

  2006cited by this paper
• Pd(OAc)2/DABCO-catalyzed Suzuki–Miyaura cross-coupling reaction in DMF

  2006cited by this paper
• A highly active catalyst for Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.

  2006cited by this paper
• Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure.

  2005cited by this paper
• Electronic nature of N-heterocyclic carbene ligands: effect on the Suzuki reaction.

  2005cited by this paper
• A rationally designed universal catalyst for Suzuki-Miyaura coupling processes.

  2004cited by this paper
• Use of highly reactive, versatile and air-stable palladium-phosphinous acid complex [(t-Bu)2P(OH)]2PdCl2 (popd) as a catalyst for the optimized Suzuki-Miyaura cross-coupling of less reactive heteroaryl chlorides and arylboronic acids

  2004cited by this paper
• Efficient catalyst for the Suzuki-Miyaura coupling of potassium aryl trifluoroborates with aryl chlorides.

  2004cited by this paper
• Sterically demanding, bioxazoline-derived N-heterocyclic carbene ligands with restricted flexibility for catalysis.

  2004cited by this paper
• Ruthenium-catalyzed oxidative coupling and cyclization between 2-aminobenzyl alcohol and secondary alcohols leading to quinolines

  2003cited by this paper
• Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of potassium aryl- and heteroaryltrifluoroborates.

  2003cited by this paper
• Efficient Synthesis of Substituted Terphenyls by Suzuki Coupling Reaction

  2002cited by this paper
• Boronic acids: new coupling partners in room-temperature Suzuki reactions of alkyl bromides. Crystallographic characterization of an oxidative-addition adduct generated under remarkably mild conditions.

  2002cited by this paper
• Palladium-catalyzed coupling reactions of aryl chlorides.

  2002cited by this paper
• A defined N-heterocyclic carbene complex for the palladium-catalyzed Suzuki cross-coupling of aryl chlorides at ambient temperatures.

  2002cited by this paper
• Cross-coupling reaction of organoboron compounds via base-assisted transmetalation to palladium(II) complexes

  2002cited by this paper
• Palladium-catalyzed borylation of aryl halides or triflates with dialkoxyborane: A novel and facile synthetic route to arylboronates

  2000cited by this paper
• Chemistry of Group 13 element-transition metal linkage — the platinum- and palladium-catalyzed reactions of (alkoxo)diborons

  2000cited by this paper
• Suzuki Cross-Coupling Reaction of Sterically Hindered Aryl Boronates with 3-Iodo-4-methoxybenzoic Acid Methylester

  2000cited by this paper
• Synthesis of Organoboron Compounds via the Transition Metal-Catalyzed Addi-tion and Coupling Reaction of (Alkoxo) diborons

  1999cited by this paper
• Novel Palladium(0)-Catalyzed Coupling Reaction of Dialkoxyborane with Aryl Halides: Convenient Synthetic Route to Arylboronates

  1997cited by this paper
• A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides

  1980cited by this paper
• Methods of elemento-organic chemistry

  1967cited by this paper

• GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1.

  2023cites this paper
• Transition Metal-Free Heteroarylation of Quinoxaline: Construction of Heteroaryl-Fused Phenazines by Oxidative Coupling.

  2020cites this paper
• Recent advances in organic dyes and fluorophores comprising a 1,2,3-triazole moiety

  2020cites this paper
• Formation of Alkanes and Arenes by Coupling Reactions

  2018cites this paper
• Intramolecular Nucleophilic Substitution of ω-Haloalkylphosphine Derivatives.

  2017cites this paper
• The Influence of the Nature of the Support on the Copper–Palladium Catalysed Suzuki–Miyaura-Coupling

  2016cites this paper
• 2-Chloro-4-tetrafluorophenoxypyrimidine: a versatile reagent for C-2 prior to C-4 functionalizations

  2016cites this paper
• Deactivation in homogeneous transition metal catalysis: causes, avoidance, and cure.

  2015cites this paper
• Selective mono-amination of dichlorodiazines

  2015cites this paper
• Convenient access to readily soluble symmetrical dialkyl-substituted α-oligofurans.

  2014cites this paper
• Microwave‐Assisted Synthesis of Substituted Pyrrolo[2,3‐d]pyrimidines

  2014cites this paper
• Metal Catalyzed Cross-Coupling Reactions in the Decoration of Pyrimidine, Pyridazine, and Pyrazine

  2014cites this paper
• An efficient and simple ligand from phthalandione for palladium-catalyzed Suzuki reaction in aqueous media

  2014cites this paper
• Application of cooperative iron/copper catalysis to a palladium-free borylation of aryl bromides with pinacolborane.

  2014cites this paper
• Synthesis and Photophysical Properties of Push–Pull Structures Incorporating Diazines as Attracting Part with a Fluorene Core

  2013cites this paper
• Mild Rh(III)-catalyzed C-H activation and annulation with alkyne MIDA boronates: short, efficient synthesis of heterocyclic boronic acid derivatives.

  2012cites this paper
• Suzuki reactions of aryl bromides catalyzed by amidoxime Fibers-palladiumII complex

  2012cites this paper
• A C-H borylation approach to Suzuki-Miyaura coupling of typically unstable 2-heteroaryl and polyfluorophenyl boronates.

  2012cites this paper