TLR4 Hyperresponsiveness via Cell Surface Expression of Heat Shock Protein gp96 Potentiates Suppressive Function of Regulatory T Cells1

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Immunology

• Publication date

  2007-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.178.5.3219PMID 17312170
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Essential roles of IL‐12 and dendritic cells but not IL‐23 and macrophages in lupus‐like diseases initiated by cell surface HSP gp96

  2007cited by this paper
• FOXP3 controls regulatory T cell function through cooperation with NFAT.

  2006cited by this paper
• TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease1

  2006influential reference
• Toll-like receptors and innate immunity

  2006cited by this paper
• FOXP3: of mice and men.

  2006cited by this paper
• Comment on “CCR7 Is Critically Important for Migration of Dendritic Cells in Intestinal Lamina Propria to Mesenteric Lymph Nodes”

  2006cited by this paper
• Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells1

  2006cited by this paper
• Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling.

  2006cited by this paper
• From vanilla to 28 flavors: multiple varieties of T regulatory cells.

  2006cited by this paper
• Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells.

  2006influential reference
• MD1 Expression Regulates Development of Regulatory T Cells

  2006cited by this paper
• Toll-like receptor 2 controls expansion and function of regulatory T cells.

  2006influential reference
• Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

  2006influential reference
• Middle-Age Male Mice Have Increased Severity of Experimental Autoimmune Encephalomyelitis and Are Unresponsive to Testosterone Therapy1

  2005cited by this paper
• Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory Cells1

  2005cited by this paper
• Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

  2005influential reference
• Natural versus adaptive regulatory T cells.

  2005cited by this paper
• Toll-Like Receptor 8-Mediated Reversal of CD4+ Regulatory T Cell Function

  2005cited by this paper
• Failure of CD25+ T Cells from Lupus-Prone Mice to Suppress Lupus Glomerulonephritis and Sialoadenitis1

  2005cited by this paper
• Toll-dependent control mechanisms of CD4 T cell activation.

  2004cited by this paper
• Cutting Edge: IL-2 Is Critically Required for the In Vitro Activation of CD4+CD25+ T Cell Suppressor Function

  2004influential reference
• A Sudden Decline in Active Membrane-Bound TGF-β Impairs Both T Regulatory Cell Function and Protection against Autoimmune Diabetes1

  2004cited by this paper
• Toll-like receptor control of the adaptive immune responses

  2004cited by this paper
• Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells.

  2004cited by this paper
• TLR2 is expressed on activated T cells as a costimulatory receptor.

  2004cited by this paper
• Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells

  2004cited by this paper
• Functional assay for human CD4+CD25+ Treg cells reveals an age‐dependent loss of suppressive activity

  2003cited by this paper
• Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic Cells

  2003cited by this paper
• Regulatory T Cells Selectively Express Toll-like Receptors and Are Activated by Lipopolysaccharide

  2003influential reference
• Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

  2003cited by this paper
• Control of Immune Responses by Naturally Arising CD4+ Regulatory T Cells That Express Toll-like Receptors

  2003cited by this paper
• Differential effect of neonatal thymectomy on systemic and organ-specific autoimmune disease.

  2002cited by this paper
• Innate immune recognition.

  2002cited by this paper
• Cutting Edge: Depletion of CD4+CD25+ Regulatory T Cells Is Necessary, But Not Sufficient, for Induction of Organ-Specific Autoimmune Disease

  2002cited by this paper
• CD4+CD25+ suppressor T cells: more questions than answers

  2002cited by this paper
• Interleukin 2 Signaling Is Required for CD4+ Regulatory T Cell Function

  2002influential reference
• CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.

  2002cited by this paper
• Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability

  2001cited by this paper
• B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.

  2000cited by this paper
• Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

  2000cited by this paper
• Post‐thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti‐H/K ATPase‐ reactive T cells

  1999cited by this paper
• Administration of anti‐interleukin‐2 receptor α antibody in vivo induces localized autoimmune disease

  1996cited by this paper
• Post-thymectomy autoimmunity: abnormal T-cell homeostasis.

  1995cited by this paper
• Lipopolysaccharide interferes with the induction of peripheral T cell death.

  1995cited by this paper
• Genetic susceptibility to post-thymectomy autoimmune diseases in mice

  1981cited by this paper

• GRP94 is an IGF-1R chaperone and regulates beta cell death in diabetes

  2024cites this paper
• Molecular Linking of HIPEC (Hyperthermic Intraperitoneal Chemotherapy) and Tregs (Regulatory T- cells) in Advanced Epithelial Ovarian Cancer - A Review

  2021cites this paper
• Roles, Mechanisms, and Opportunities of Heat Shock Protein gp96/grp94 in Infections and Inflammation-Associated Malignancies

  2018cites this paper
• Reconstitution of Th17, Tc17 and Treg cells after paediatric haematopoietic stem cell transplantation: Impact of interleukin-7.

  2018cites this paper
• Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria

  2018cites this paper
• B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex.

  2018cites this paper
• Enhanced expression of PD‐L1 and IFN‐&ggr; on dendritic cells is associated with BCG‐induced Th2 inhibition

  2017cites this paper
• HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells

  2017cites this paper
• Physiologic Doses of Bilirubin Contribute to Tolerance of Islet Transplants by Suppressing the Innate Immune Response

  2017cites this paper
• Surface Expression of TGFβ Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer.

  2016cites this paper
• Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96

  2016cites this paper
• Molecular mechanisms of regulation of Toll‐like receptor signaling

  2016cites this paper
• Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.

  2016cites this paper
• Lentinan ameliorates burn sepsis by attenuating CD4+ CD25+ Tregs.

  2016cites this paper
• Immune response to intrapharyngeal LPS in neonatal and juvenile mice.

  2015cites this paper
• Plasma membrane gp96 enhances invasion and metastatic potential of liver cancer via regulation of uPAR

  2015cites this paper
• Cell surfactomes of two endometrial epithelial cell lines that differ in their adhesiveness to embryonic cells

  2014cites this paper
• Toll-Like Receptor 4 Stimulation before or after Streptococcus pneumoniae Induced Sepsis Improves Survival and Is Dependent on T-Cells

  2014cites this paper
• Heat Shock Proteins: Intestinal Gatekeepers that Are Influenced by Dietary Components and the Gut Microbiota

  2014cites this paper
• Sex Differences in monocytes and TLR4 associated immune responses; implications for systemic lupus erythematosus (SLE).

  2014cites this paper
• MyD88 mediates the decision to die by apoptosis or necroptosis after UV irradiation

  2014cites this paper
• The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics

  2014cites this paper
• Role of toll‐like receptors in liver transplantation

  2014cites this paper
• Cellular Mechanisms of Adaptive Immunity

  2014cites this paper
• Deletion of CD24 Impairs Development of Heat Shock Protein gp96–Driven Autoimmune Disease through Expansion of Myeloid-Derived Suppressor Cells

  2014cites this paper
• Heat Shock Proteins and Regulatory T Cells

  2013cites this paper
• Total coumarins from Urtica dentata Hand prevent murine autoimmune diabetes via suppression of the TLR4-signaling pathways.

  2013cites this paper
• The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis.

  2013cites this paper
• Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

  2013cites this paper
• Investigating Gp96 Biology and its Macrophage-Intrinsic Role in Colitis-Associated Colon Tumorigenesis

  2013cites this paper
• Induction of Regulatory T Cells by High-Dose gp96 Suppresses Murine Liver Immune Hyperactivation

  2013influential citation
• Udział receptorów TLR rozpoznających wzorce molekularne organizmów patogennych w modulowaniu aktywności regulatorowych limfocytów T CD4+CD25+FoxP3+

  2011cites this paper
• Regulatory T-cell depletion synergizes with gp96-mediated cellular responses and antitumor activity

  2011cites this paper
• Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by toll-like receptor-4.

  2011cites this paper
• Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ cells is enabled by IL-2.

  2010cites this paper
• [Implementation of the intestinal micro flora in the early stage and adequate immunity later on].

  2010cites this paper
• Treg suppress CTL responses upon immunization with HSP gp96

  2009cites this paper
• Alternative and additional mechanisms to the hygiene hypothesis

  2009cites this paper
• Steroid treatments in mice do not alter the number and function of regulatory T cells, but amplify cyclophosphamide-induced autoimmune disease.

  2009cites this paper
• Regulatory T cells and Toll-like receptors: what is the missing link?

  2009cites this paper
• This information is current as Inflammatory Responses with gp 96 via CD 91 and Regulate Human Plasmacytoid Dendritic Cells Interact

  2008cites this paper
• Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic T cell responses.

  2008cites this paper
• Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses1

  2008cites this paper
• Burkholderia pseudomallei Infection of T Cells Leads to T-Cell Costimulation Partially Provided by Flagellin

  2008cites this paper
• T-regulatory cells in systemic lupus erythematosus

  2008cites this paper
• Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: role of inhaled corticosteroid.

  2008cites this paper
• Toll-like receptor signaling in transplantation.

  2008cites this paper