Further analysis of the inhibition by agmatine on the cardiac sympathetic outflow: Role of the &agr;2‐adrenoceptor subtypes

No abstract is available for this paper.

• Publication year

  2017

• Venue

  European Journal of Pharmacology

• Publication date

  2017-06-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.ejphar.2017.03.009PMID 28315344
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999influential reference
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