Dietary Omega-3 Fatty Acids and Susceptibility to Ventricular Fibrillation: Lack of Protection and a Proarrhythmic Effect

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Circulation: Arrhythmia and Electrophysiology

• Publication date

  2012-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/CIRCEP.111.966739PMID 22333345PMCID PMC3380163
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• n-3 Fatty acids in cardiovascular disease.

  2011cited by this paper
• Efficacy and Safety of Prescription Omega-3 Fatty Acids for the Prevention of Recurrent Symptomatic Atrial Fibrillation: A Randomized Controlled Trial

  2011cited by this paper
• n-3 fatty acids in cardiovascular disease.

  2011cited by this paper
• OMEGA, a Randomized, Placebo-Controlled Trial to Test the Effect of Highly Purified Omega-3 Fatty Acids on Top of Modern Guideline-Adjusted Therapy After Myocardial Infarction

  2010cited by this paper
• n-3 fatty acids and cardiovascular events after myocardial infarction.

  2010cited by this paper
• Efficacy and safety of prescription omega-3 fatty acids for the prevention of recurrent symptomatic atrial fibrillation: a randomized controlled trial.

  2010cited by this paper
• Omega-3 fatty acids in high-risk cardiovascular patients: a meta-analysis of randomized controlled trials

  2010cited by this paper
• Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: effect of endurance exercise training.

  2009cited by this paper
• Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: A meta-analysis of randomized controlled trials

  2009cited by this paper
• Redox modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death.

  2009cited by this paper
• Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial.

  2008cited by this paper
• Effect of fish oil on ventricular tachyarrhythmia in three studies in patients with implantable cardioverter defibrillators.

  2008cited by this paper
• Effect of fish oil on arrhythmias and mortality: systematic review

  2008cited by this paper
• Fish-oil supplementation in patients with implantable cardioverter defibrillators: a meta-analysis

  2008cited by this paper
• Repolarization abnormalities and afterdepolarizations in a canine model of sudden cardiac death.

  2008cited by this paper
• Red blood cell omega-3 fatty acids and the risk of ventricular arrhythmias in patients with heart failure.

  2008cited by this paper
• Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts.

  2007cited by this paper
• Pro- and antiarrhythmic properties of a diet rich in fish oil.

  2007cited by this paper
• Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.

  2007cited by this paper
• Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial.

  2006cited by this paper
• A Review of Omega-3 Ethyl Esters for Cardiovascular Prevention and Treatment of Increased Blood Triglyceride Levels

  2006cited by this paper
• A Review of Omega-3 Ethyl Esters for Cardiovascular Prevention and Treatment of Increased Blood Triglyceride Levels

  2006cited by this paper
• A comprehensive review and analysis of 25 years of data from an in vivo canine model of sudden cardiac death: implications for future anti-arrhythmic drug development.

  2006cited by this paper
• Prevention of Fatal Arrhythmias in High-Risk Subjects by Fish Oil n-3 Fatty Acid Intake

  2005cited by this paper
• Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial.

  2005cited by this paper
• A systematic review and meta-analysis of the impact of omega-3 fatty acids on selected arrhythmia outcomes in animal models.

  2005cited by this paper
• Antiarrhythmic and electrophysiological effects of long-chain ω-3 polyunsaturated fatty acids

  2005cited by this paper
• Antiarrhythmic and electrophysiological effects of long-chain omega-3 polyunsaturated fatty acids.

  2005cited by this paper
• Omega 3 fatty acids for prevention and treatment of cardiovascular disease.

  2004cited by this paper
• Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic Rabbits.

  2004cited by this paper
• Omega-3 Fatty Acids and Cardiovascular Disease: New Recommendations From the American Heart Association

  2003cited by this paper
• Heterogeneous Regional Endocardial Repolarization is Associated with Increased Risk for Ischemia‐Dependent Ventricular Fibrillation after Myocardial Infarction

  2003cited by this paper
• Lack of benefit of dietary advice to men with angina: results of a controlled trial

  2003cited by this paper
• Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction Time-Course Analysis of the Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione

  2002cited by this paper
• Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction: Time-Course Analysis of the Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione

  2002cited by this paper
• Blood levels of long-chain n-3 fatty acids and the risk of sudden death.

  2002cited by this paper
• Arrhythmic and sudden death in chronic ischemic heart disease--a review of epidemiological data.

  2002cited by this paper
• Effects of a high-dose concentrate of n-3 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol.

  2001cited by this paper
• Epidemiology of Arrhythmic and Sudden Death in the Chronic Phase of Ischemic Heart Disease

  1999cited by this paper
• Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs.

  1999cited by this paper
• Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

  1999cited by this paper
• Do animal models have clinical value?

  1998cited by this paper
• Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators.

  1998cited by this paper
• Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction

  1998cited by this paper
• Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest.

  1995cited by this paper
• Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids.

  1994cited by this paper
• Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey.

  1992cited by this paper
• Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART).

  1989cited by this paper
• The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion.

  1988cited by this paper
• Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion.

  1988cited by this paper
• Autonomic mechanisms and sudden death. New insights from analysis of baroreceptor reflexes in conscious dogs with and without a myocardial infarction.

  1988cited by this paper
• The inverse relation between fish consumption and 20-year mortality from coronary heart disease.

  1985cited by this paper
• Autonomic mechanisms in ventricular fibrillation induced by myocardial ischemia during exercise in dogs with healed myocardial infarction. An experimental preparation for sudden cardiac death.

  1984cited by this paper
• Baroreceptor Reflex Control of Heart Rate: A Predictor of Sudden Cardiac Death

  1982cited by this paper
• Ischemia at a Distance After Acute Myocardial Infarction: A Cause of Early Postinfarction Angina

  1980cited by this paper
• Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis?

  1978cited by this paper
• PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL.

  1964cited by this paper
• A rapid method of total lipid extraction and purification.

  1959cited by this paper

• Pro-Arrhythmic Effect of Chronic Stress-Associated Humoral Factors in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

  2025cites this paper
• Omega-3 Fatty Acids and Arrhythmias

  2024cites this paper
• Diet and Sudden Death: How to Reduce the Risk.

  2022cites this paper
• Plasma Omega‐3 Fatty Acids and the Risk of Cardiovascular Events in Patients After an Acute Coronary Syndrome in MERLIN‐TIMI 36

  2021cites this paper
• Polyunsaturated fatty acid‐derived IKs channel activators shorten the QT interval ex‐vivo and in‐vivo

  2020cites this paper
• Anti-arrhythmic properties of non-antiarrhythmic medications

  2020cites this paper
• Fish Oil Dilemma: Does It Increase the Risk of Ventricular Arrhythmias and Death? Can Fish Oil Kill You?

  2020cites this paper
• Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs

  2017cites this paper
• Characterising in vivo cardiac function in the rat following supplementation of human dietary achievable fish oil doses

  2017cites this paper
• The pro‐ or antiarrhythmic actions of polyunsaturated fatty acids and of cholesterol☆

  2017cites this paper
• Up-Regulation of Mitochondrial Antioxidant Superoxide Dismutase Underpins Persistent Cardiac Nutritional-Preconditioning by Long Chain n-3 Polyunsaturated Fatty Acids in the Rat

  2016cites this paper
• Cardioprotective effects of omega 3 fatty acids: origin of the variability

  2016cites this paper
• Chronic Omega-3 Polyunsaturated Fatty Acid Treatment Variably Affects Cellular Repolarization in a Healed Post-MI Arrhythmia Model

  2016influential citation
• Omega-3 fatty acids in cardiovascular disease--an uphill battle.

  2015cites this paper
• The effect of omega-3 polyunsaturated fatty acids enriched diet on the contractile function, structure, Ca2+ handling and electrophysiology in the rat heart**

  2015cites this paper
• Effects of Omega-3 Fatty Acids in Cardiac Arrhythmias

  2014cites this paper
• Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids

  2014cites this paper
• Attenuation of Cardiac Fibrillation Vulnerability by n-3 Polyunsaturated Fatty Acids in a Rat Model of Cardiomyopathy

  2014cites this paper
• Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study

  2013cites this paper
• Dietary Omega-3 Fatty Acids Promote Arrhythmogenic Remodeling of Cellular Ca2+ Handling in a Postinfarction Model of Sudden Cardiac Death

  2013cites this paper
• Current World Literature

  2013cites this paper
• Omega-3 fatty acids and cardiac arrhythmias

  2013cites this paper
• The effects of omega-3 polyunsaturated fatty acids on cardiac rhythm: a critical reassessment.

  2013influential citation
• Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?

  2013cites this paper
• Recent findings on the health effects of omega-3 fatty acids and statins , and their interactions : do statins inhibit omega-3 ?

  2013cites this paper
• Effect of Dietary Omega-3 Polyunsaturated Fatty Acids on Heart Rate and Heart Rate Variability in Animals Susceptible or Resistant to Ventricular Fibrillation

  2012cites this paper
• Omega-3 Fatty Acids: Anti-Arrhythmic, Pro-Arrhythmic, or Both?

  2012cites this paper
• How Are n-3 LCPUFAs Antiarrhythmic? A Reassessment of n-3 LCPUFAs in Cardiac Disease

  2012influential citation
• Fish oil for atrial fibrillation prevention: can we intervene soon enough to make a difference?

  2012cites this paper
• Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation

  2012cites this paper
• Omega-3 fatty acids, ventricular arrhythmias, and sudden cardiac death: antiarrhythmic, proarrhythmic, or neither.

  2012cites this paper
• Are the anti-arrhythmic effects of omega-3 fatty acids due to modulation of myocardial calcium handling?

  2012cites this paper
• Omega-3 polyunsaturated fatty acids and cardiac rhythm: an introduction

  2012cites this paper