Targeting Immune Complex-Mediated Hypersensitivity with Recombinant Soluble Human FcγRIA (CD64A)1

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Immunology

• Publication date

  2008-01-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.4049/jimmunol.180.1.580PMID 18097060
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A general theory for the precipitin reaction--based on Fc-mediated precipitation.

  2009cited by this paper
• Activating and inhibitory FcγRs in autoimmune disorders

  2006cited by this paper
• Fc receptors and their interaction with complement in autoimmunity.

  2005cited by this paper
• Animal models of rheumatoid arthritis and their relevance to human disease.

  2005cited by this paper
• Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.

  2005cited by this paper
• Immune complex-mediated tissue injury: a multistep paradigm.

  2005cited by this paper
• The role of FcγRIIA and IIIA polymorphisms in autoimmune diseases

  2004cited by this paper
• Human antibody–Fc receptor interactions illuminated by crystal structures

  2004influential reference
• Soluble FcγRIIa inhibits rheumatoid factor binding to immune complexes

  2003cited by this paper
• Fc receptors are major mediators of antibody based inflammation in autoimmunity.

  2002cited by this paper
• FcγRI-Deficient Mice Show Multiple Alterations to Inflammatory and Immune Responses

  2002cited by this paper
• FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

  2002cited by this paper
• A full complement of receptors in immune complex diseases.

  2002cited by this paper
• Interaction sites on human IgG-Fc for FcγR: current models

  2002cited by this paper
• Roles of Fc receptors in autoimmunity

  2002influential reference
• The genetic and immunopathological processes underlying collagen‐induced arthritis

  2001cited by this paper
• Cytokine pathways and joint inflammation in rheumatoid arthritis.

  2001cited by this paper
• Characterization and crystallization of soluble human Fc gamma receptor II (CD32) isoforms produced in insect cells.

  1999cited by this paper
• A dominant role for mast cell Fc receptors in the Arthus reaction.

  1996cited by this paper
• Release of Fc gamma RIIa2 by activated platelets and inhibition of anti-CD9-mediated platelet aggregation by recombinant Fc gamma RIIa2.

  1995cited by this paper
• Recombinant soluble Fc gamma RII inhibits immune complex precipitation.

  1995cited by this paper
• Recombinant soluble FcγRII inhibits immune complex precipitation

  1995cited by this paper
• Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade.

  1994cited by this paper
• Human epidermal Langerhans cells secrete a soluble receptor for IgG (Fc gamma RII/CD32) that inhibits the binding of immune complexes to Fc gamma R+ cells.

  1994cited by this paper
• Recombinant soluble human Fc gamma RII: production, characterization, and inhibition of the Arthus reaction

  1993cited by this paper
• Induction of arthritis with monoclonal antibodies to collagen.

  1992influential reference
• The immunoglobulin superfamily--domains for cell surface recognition.

  1988cited by this paper
• Cloned and expressed human Fc receptor for IgG mediates anti-CD3-dependent lymphoproliferation.

  1988cited by this paper
• The half‐lives of serum immunoglobulins in adult mice

  1988cited by this paper
• The bulk of endogenously produced IgG2a is eliminated from the serum of adult C57BL/6 mice with a half‐life of 6–8 days

  1986cited by this paper
• Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker.

  1982cited by this paper

• A Comprehensive Review of Fc Gamma Receptors and Their Role in Systemic Lupus Erythematosus

  2025cites this paper
• The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function

  2023cites this paper
• Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice

  2022cites this paper
• Soybean allergy: characteristics, mechanisms, detection and its reduction through novel food processing techniques

  2022cites this paper
• The prospects for targeting FcR as a novel therapeutic strategy in rheumatoid arthritis.

  2020cites this paper
• Neuronal FcγRI mediates acute and chronic joint pain.

  2019influential citation
• The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens

  2018cites this paper
• Immune Complexes in Systemic Lupus Erythematosus

  2016cites this paper
• Renal dendritic cells sample blood-borne antigen and guide T-cell migration to the kidney by means of intravascular processes.

  2016cites this paper
• Fc gamma receptors: glycobiology and therapeutic prospects

  2016cites this paper
• Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding

  2015cites this paper
• Targeting the Fc receptor in autoimmune disease

  2014cites this paper
• The binding of soluble recombinant human Fcγ receptor I for human immunoglobulin G is conferred by its first and second extracellular domains.

  2013cites this paper
• Experimental Models of Mixed Cryoglobulinemia

  2012cites this paper
• RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

  2012cites this paper
• Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond

  2012cites this paper
• Neuronal Fc gamma receptor I as a novel mediator for IgG immune complex-induced peripheral sensitization☆

  2012cites this paper
• Effective expression of soluble aglycosylated recombinant human Fcγ receptor I by low translational efficiency in Escherichia coli

  2012cites this paper
• Engineering of recombinant human Fcγ receptor I by directed evolution.

  2012cites this paper
• HCV infection and cryoglobulinemia

  2012cites this paper
• JPET #187740 RN486 [6-Cyclopropyl-8-fluoro-2-(2-hydroxymethyl-3-{1-methyl-5-[5-(4-methyl- piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridin-3-yl}-phenyl)-2H- isoquinolin-1-one], a Selective Bruton’s Tyrosine Kinase (Btk) Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis

  2011cites this paper
• Crystal Structure of Fcγ Receptor I and Its Implication in High Affinity γ-Immunoglobulin Binding*

  2011cites this paper
• Chapter 19 – Immune Complexes in Systemic Lupus Erythematosus

  2011cites this paper
• Importance of Neonatal FcR in Regulating the Serum Half-Life of Therapeutic Proteins Containing the Fc Domain of Human IgG1: A Comparative Study of the Affinity of Monoclonal Antibodies and Fc-Fusion Proteins to Human Neonatal FcR

  2010cites this paper
• Proteins to Human Neonatal FcR Monoclonal Antibodies and Fc-Fusion Comparative Study of the Affinity of Containing the Fc Domain of Human IgG 1 : A the Serum Half-Life of Therapeutic Proteins Importance of Neonatal FcR in Regulating

  2010cites this paper
• Efficient expression and purification of human aglycosylated Fcγ receptors in Escherichia coli

  2010cites this paper
• FcγRIIB, FcγRIIIB, and systemic lupus erythematosus

  2010cites this paper
• Generation of a high-affinity Fcgamma receptor by Ig-domain swapping between human CD64A and CD16A.

  2010cites this paper
• Collagen-Induced Arthritis ( CD 64 A ) Reduces Inflammation in Murine R 1 A γ Recombinant Soluble Human Fc

  2009influential citation
• Grading the commercial optical biosensor literature—Class of 2008: ‘The Mighty Binders’

  2009cites this paper
• Recombinant Soluble Human FcγR1A (CD64A) Reduces Inflammation in Murine Collagen-Induced Arthritis1

  2009cites this paper
• Role of antibodies and T cells in pigeon fanciers' lung

  2009influential citation
• Hypersensitivity Reactions and Methods of Detection

  2009cites this paper
• When is a malaria immune complex not an immune complex?

  2009cites this paper