Hydrolysis study: Synthesis of novel styrenic Schiff bases derived from benzothiazole

Abstract Novel styrenic Schiff base derivatives of benzothiazole are synthesized. The condensation of 4-vinylbenzaldehyde 1 with either benzothiazol-2-amine or 4-methoxy-benzothiazol-2-amine leads to a mixture of two isomers. From 4-methyl-benzothiazol-2-amine and 6-fluoro-benzothiazol-2-amine, the N-(4-vinylbenzylidene)-4-methyl-benzothiazol-2-amine 8 and N-(4-vinylbenzylidene)-6-fluoro-benzothiazol-2-amine 9 are isolated, respectively. The structures of the synthesized Schiff bases are confirmed through a combination of various spectroscopic techniques including IR, UV, 1H and 13C NMR. A kinetic study of the hydrolysis process of derivatives 6 and 9 in buffered aqueous medium at pH 4.4, 7.4 and 8.5 is conducted by UV spectroscopy. It is shown that the hydrolysis of these compounds is a first order reaction showing an increasing rate as the medium acidity is enhanced.

• Publication year

  2012

• Venue

  Arabian Journal of Chemistry

• Publication date

  2012-04-01

• Fields of study

  Chemistry

• Identifiers
  DOI 10.1016/J.ARABJC.2010.10.022
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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