A 7-bp insertion in the 3' untranslated region suggests the duplication and concerted evolution of the rabbit SRY gene

In this work we report the genetic polymorphism of a 7-bp insertion in the 3' untranslated region of the rabbit SRY gene. The polymorphic GAATTAA motif was found exclusively in one of the two divergent rabbit Y-chromosomal lineages, suggesting that its origin is more recent than the separation of the O. c. algirus and O. c. cuniculus Y-chromosomes. In addition, the remarkable observation of haplotypes exhibiting 0, 1 and 2 7-bp inserts in essentially all algirus populations suggests that the rabbit SRY gene is duplicated and evolving under concerted evolution.

• Publication year

  2006

• Venue

  Genetics Selection Evolution

• Publication date

  2006-04-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/1297-9686-38-3-313PMID 16635452PMCID 2689287
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• High levels of nucleotide diversity in the European rabbit (Oryctolagus cuniculus) SRY gene.

  2005cited by this paper
• The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes

  2003cited by this paper
• Abundant gene conversion between arms of palindromes in human and ape Y chromosomes

  2003cited by this paper
• Animal Cytogenetics and Comparative Mapping

  2003cited by this paper
• De la Garenne au Clapier: Étude Archéozoologique du Lapin en Europe Occidentale

  2003influential reference
• Establishment of an R-banded rabbit karyotype nomenclature by FISH localization of 23 chromosome-specific genes on both G- and R-banded chromosomes

  2003cited by this paper
• POSTGLACIAL DISPERSAL OF THE EUROPEAN RABBIT (ORYCTOLAGUS CUNICULUS) ON THE IBERIAN PENINSULA RECONSTRUCTED FROM NESTED CLADE AND MISMATCH ANALYSES OF MITOCHONDRIAL DNA GENETIC VARIATION

  2002cited by this paper
• Mapping the SRY gene in Microtus cabrerae: a vole species with multiple SRY copies in males and females.

  2002cited by this paper
• Stationary distributions of microsatellite loci between divergent population groups of the European rabbit (Oryctolagus cuniculus).

  2001cited by this paper
• Construction of a rabbit bacterial artificial chromosome (BAC) library: application to the mapping of the major histocompatibility complex to position 12q1.1

  2001cited by this paper
• Phylogeography of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula inferred from RFLP analysis of the cytochrome b gene

  2000cited by this paper
• Evidence for multiple functional copies of the male sex-determining locus, sry, in African murine rodents

  1997cited by this paper
• Rabbit and man: genetic and historic approach

  1994cited by this paper
• The testis-determining gene, SRY, exists in multiple copies in Old World rodents.

  1994cited by this paper
• Inverted repeat structure of the Sry locus in mice.

  1992cited by this paper
• Mitochondrial DNA evolution in lagomorphs: Origin of systematic heteroplasmy and organization of diversity in European rabbits

  1991cited by this paper

• Identification of six candidate genes for endometrial carcinoma by bioinformatics analysis

  2020cites this paper
• The evolutionary history of grey wolf Y chromosomes

  2019cites this paper
• Copy Number Variations of Four Y-Linked Genes in Swamp Buffaloes

  2019cites this paper
• Eight Y chromosome genes show copy number variations in horses

  2018cites this paper
• Copy number variations of five Y chromosome genes in donkeys

  2017cites this paper
• Large-scale assessment of myxomatosis prevalence in European wild rabbits (Oryctolagus cuniculus) 60years after first outbreak in Spain.

  2017cites this paper
• Switching on sex: transcriptional regulation of the testis-determining gene Sry

  2014cites this paper
• The Y‐Chromosome

  2013cites this paper
• Unexpected functional similarities between gatekeeper tumour suppressor genes and proto-oncogenes revealed by systems biology

  2011cites this paper
• Population genetic structure and history of fragmented remnant populations of the New England cottontail (Sylvilagus transitionalis)

  2011cites this paper
• A Gene Catalogue of the Euchromatic Male-Specific Region of the Horse Y Chromosome: Comparison with Human and Other Mammals

  2011cites this paper
• Virus-host adatation and co-evolution of myxoma virus (MV) and rabbit haemorrhagic disease virus (RHDV) in their natural host, the wild rabbit (oryctolagus cuniculus)

  2011cites this paper
• Molecular heterogeneity of XY sex reversal in horses.

  2010cites this paper
• Extensive gene conversion drives the concerted evolution of paralogous copies of the SRY gene in European rabbits.

  2010cites this paper
• The genomic legacy from the extinct Lepus timidus to the three hare species of Iberia: contrast between mtDNA, sex chromosomes and autosomes

  2009cites this paper
• Discovery of candidate genes for stallion fertility from the horse Y chromosome

  2009cites this paper
• Reduced introgression of the Y chromosome between subspecies of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula

  2008cites this paper
• Gene discovery and comparative analysis of X-degenerate genes from the domestic cat Y chromosome.

  2008cites this paper
• Inferring the Evolutionary History of the European Rabbit (Oryctolagus cuniculus) from Molecular Markers

  2008cites this paper
• Y-chromosomal markers for the European brown hare (Lepus europaeus, Pallas 1778)

  2007cites this paper
• Patterns of hemoglobin polymorphism [α-globin (HBA) and β-globin (HBB)] across the contact zone of two distinct phylogeographic lineages of the European rabbit (Oryctolagus cuniculus)

  2007cites this paper
• Current perspectives in phylogeography and the significance of South European refugia in the creation and maintenance of European biodiversity

  2007cites this paper
• Molecular Sex Determination Using Sexual Dimorphisms between ZFX and ZFY Genes in Korean Hares(Lepus coreanus Thomas)

  2007cites this paper
• Evolutionary genetics and incipient speciation in the European rabbit (Oryctolagus cuniculus) : insights from the analysis of nucleotide polymorphism at mtDNA and sex chromosomes

  2006cites this paper