Highly frequent allelic loss of chromosome 6q16-23 in osteosarcoma: involvement of cyclin C in osteosarcoma.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  International Journal of Molecular Medicine

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/IJMM.18.6.1153PMID 17089020
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cyclin C/cdk3 promotes Rb-dependent G0 exit.

  2004cited by this paper
• Allelic Loss of Chromosome 6q in Gastric Carcinoma

  2003cited by this paper
• Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma

  2003cited by this paper
• Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors.

  2003cited by this paper
• Defining the region(s) of deletion at 6q16–q22 in human prostate cancer

  2002cited by this paper
• Genetic imbalances revealed by comparative genomic hybridization in osteosarcomas

  2002cited by this paper
• Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma

  2001cited by this paper
• Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma.

  2000cited by this paper
• Cyclin C is a primary 1alpha,25-dihydroxyvitamin D(3) responding gene.

  2000cited by this paper
• TFIIH is negatively regulated by cdk8-containing mediator complexes

  2000cited by this paper
• Chromosomal regions involved in the pathogenesis of osteosarcomas.

  1999cited by this paper
• DNA sequence copy number increase at 8q: A potential new prognostic marker in high‐grade osteosarcoma

  1999cited by this paper
• CDK4 gene amplification in osteosarcoma: Reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons

  1999cited by this paper
• CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations.

  1998cited by this paper
• Frequent loss of heterozygosity on the long arm of chromosome 6: identification of two distinct regions of deletion in childhood acute lymphoblastic leukemia.

  1998cited by this paper
• Cytogenetic findings in 73 osteosarcoma specimens and a review of the literature.

  1997cited by this paper
• Cyclins, cyclin‐dependent kinases and differentiation

  1997cited by this paper
• Frequent reduction or loss of DCC gene expression in human osteosarcoma.

  1997cited by this paper
• Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: deletion of the CCNC gene in human tumors.

  1996cited by this paper
• Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias.

  1995cited by this paper
• Allelotype analysis in osteosarcomas: frequent allele loss on 3q, 13q, 17p, and 18q.

  1992cited by this paper

• Immunosuppressive Tumor Microenvironment of Osteosarcoma

  2025cites this paper
• Quitting Your Day Job in Response to Stress: Cell Survival and Cell Death Require Secondary Cytoplasmic Roles of Cyclin C and Med13

  2025cites this paper
• Immunosuppressive tumor microenvironment of osteosarcoma

  2024cites this paper
• Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses

  2024cites this paper
• MED12 is overexpressed in glioblastoma patients and serves as an oncogene by targeting the VDR/BCL6/p53 axis

  2022influential citation
• Cdk8 Kinase Module: A Mediator of Life and Death Decisions in Times of Stress

  2021cites this paper
• 6q deletion is frequent but unrelated to patient prognosis in breast cancer

  2021cites this paper
• The Less Known Cyclins—Uncovered

  2021influential citation
• Targeting transcription cycles in cancer

  2021cites this paper
• Mediator's Kinase Module: A Modular Regulator of Cell Fate

  2020cites this paper
• Synergistic repression of thyroid hyperplasia by cyclin C and Pten

  2019cites this paper
• Local microRNAs in peritoneal dialysis-related peritonitis

  2019cites this paper
• HACE1 is a potential tumor suppressor in osteosarcoma

  2019cites this paper
• Cyclin C: The Story of a Non-Cycling Cyclin

  2019cites this paper
• In-Vitro and In-Vivo Establishment and Characterization of Bioluminescent Orthotopic Chemotherapy-Resistant Human Osteosarcoma Models in NSG Mice

  2019cites this paper
• Reactive Oxygen Species and Mitochondrial Dynamics: The Yin and Yang of Mitochondrial Dysfunction and Cancer Progression

  2018cites this paper
• A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response

  2017cites this paper
• TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling

  2017cites this paper
• Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma.

  2017cites this paper
• HELQ reverses the malignant phenotype of osteosarcoma cells via CHK1-RAD51 signaling pathway.

  2017cites this paper
• The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma

  2016cites this paper
• Mediator kinase module and human tumorigenesis

  2015influential citation
• Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells.

  2015cites this paper
• Genomic Heterogeneity of Osteosarcoma - Shift from Single Candidates to Functional Modules

  2015cites this paper
• Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome

  2014cites this paper
• Cyclin C is a haploinsufficient tumour suppressor

  2014cites this paper
• Involvement of Mediator complex in malignancy.

  2014cites this paper
• Microarray Analysis of Cell Cycle Gene Expression in Adult Human Corneal Endothelial Cells

  2014cites this paper
• Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

  2014cites this paper
• Gene expression profile of the whole Mediator complex in human osteosarcoma and normal osteoblasts

  2013cites this paper
• The Genetics of Osteosarcoma

  2012cites this paper
• Retroviral Cyclin Enhances Cyclin-Dependent Kinase-8 Activity

  2012cites this paper
• Leukemogenesis as a new approach to investigate the correlation between up regulated gene 4/upregulator of cell proliferation (URG4/URGCP) and signal transduction genes in leukemia

  2012cites this paper
• The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8.

  2011cites this paper
• The cyclins: a family of widely expressed tumor antigens?

  2011cites this paper
• Dysregulation of CDK8 and Cyclin C in tumorigenesis.

  2011cites this paper
• Genetics of Osteosarcoma

  2010cites this paper
• Chapter 2 Interplay Between Cyclin-Dependent Kinases and E 2 F-Dependent Transcription

  2010cites this paper
• Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma.

  2010cites this paper
• Interplay Between Cyclin-Dependent Kinases and E2F-Dependent Transcription

  2010cites this paper
• Genetic and phenotypic characterization of the lymphocytic variant of the Hypereosinophilic Syndrome : a model of T lymphomagenesis

  2010cites this paper
• Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma.

  2009cites this paper
• 2. of Osteosarcoma

  2009cites this paper
• Ladder-like amplification of the type I interferon gene cluster in the human osteosarcoma cell line MG63

  2008cites this paper
• Pediatric precursor T lymphoblastic leukemia and lymphoblastic lymphoma: Differences in the common regions with loss of heterozygosity at chromosome 6q and their prognostic impact

  2008cites this paper