Vascular networks due to dynamically arrested crystalline ordering of elongated cells.

Recent experimental and theoretical studies suggest that crystallization and glass-like solidification are useful analogies for understanding cell ordering in confluent biological tissues. It remains unexplored how cellular ordering contributes to pattern formation during morphogenesis. With a computational model we show that a system of elongated, cohering biological cells can get dynamically arrested in a network pattern. Our model provides an explanation for the formation of cellular networks in culture systems that exclude intercellular interaction via chemotaxis or mechanical traction.

• Publication year

  2012

• Venue

  Physical review. E, Statistical, nonlinear, and soft matter physics

• Publication date

  2012-10-26

• Fields of study

  Biology, Materials Science, Physics, Chemistry, Medicine

• Identifiers
  DOI 10.1103/PhysRevE.87.012725arXiv 1210.7164PMID 23410377
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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