[Antimicrobial peptides in asthma pathogenesis].

Antimicrobial peptides exhibit activity against bacteria, viruses, fungi, and parasites. They have been described not only as endogenous antibiotics but also as immune modulators with an impact on innate and adaptive immune functions. Asthma is one of the most common diseases, characterized by chronic airway inflammation, bronchial hyperreactivity and asthma attacks. Airway inflammation in asthma is characterized by allergic phenotypes, such as dense infiltration of eosinophils, mast cells, Th 2 lymphocytes and monocytes. Viral infections are often the cause of asthma exacerbation. This review highlights recent observations on the role of antimicrobial peptides in asthma pathogenesis.

• Publication year

  2015

• Venue

  Postępy Higieny i Medycyny Doświadczalnej

• Publication date

  2015-01-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.5604/17322693.1135042PMID 25589709
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Właściwości biologiczne jadu pszczelego, propolisu i pyłku kwiatowego z obnóży pszczelich

  2015cited by this paper
• Vitamin D related genes in lung development and asthma pathogenesis

  2013cited by this paper
• Vitamin D in asthma and future perspectives

  2013cited by this paper
• Vitamin D, the Cutaneous Barrier, Antimicrobial Peptides and Allergies: Is There a Link?

  2013cited by this paper
• The genetic and molecular basis of plant resistance to pathogens.

  2013cited by this paper
• Honey as a source of dietary antioxidants: structures, bioavailability and evidence of protective effects against human chronic diseases.

  2013cited by this paper
• Innate immune defense system of the skin.

  2013cited by this paper
• Suppression of TLR Signaling by Targeting TIR domain-Containing Proteins

  2012cited by this paper
• [Gene and environmental interactions of food allergy].

  2012cited by this paper
• Deciphering the Magainin Resistance Process of Escherichia coli Strains in Light of the Cytosolic Proteome

  2012cited by this paper
• Role of defensins and cathelicidin LL37 in auto-immune and auto-inflammatory diseases.

  2012cited by this paper
• Mechanism of action and specificity of antimicrobial peptides designed based on buforin IIb.

  2012cited by this paper
• Antimicrobial peptides: agents of border protection for companion animals

  2012cited by this paper
• Neutrophil defensins: their possible role in allergic asthma.

  2011cited by this paper
• Insight into the mechanisms regulating immune homeostasis in health and disease.

  2011cited by this paper
• Vitamin D supplementation in children may prevent asthma exacerbation triggered by acute respiratory infection.

  2011cited by this paper
• Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren.

  2010cited by this paper
• [Defensins and cathelicidins as natural peptide antibiotics].

  2008cited by this paper
• Lipopolysaccharide-Induced Immune Responses in Relation to the TLR4(Asp299Gly) Gene Polymorphism

  2008cited by this paper
• Defensyny i katelicydyny jako naturalne antybiotyki peptydowe Defensins and cathelicidins as natural peptide antibiotics

  2008cited by this paper
• Allergic Airway Inflammation Inhibits Pulmonary Antibacterial Host Defense1

  2006cited by this paper
• Association between exposure to farming, allergies and genetic variation in CARD4/NOD1

  2006cited by this paper
• ADP-ribosyltransferase-specific Modification of Human Neutrophil Peptide-1*

  2006cited by this paper
• Association of defensin β-1 gene polymorphisms with asthma

  2005cited by this paper
• Association of defensin beta-1 gene polymorphisms with asthma.

  2005cited by this paper
• Alarmins: chemotactic activators of immune responses.

  2005cited by this paper
• [Remodeling of the basement membrane and airway epithelium in patients with asthma].

  2005cited by this paper
• Natural products with anti-HIV activity from marine organisms.

  2003cited by this paper
• ADP ribosylation of human neutrophil peptide-1 regulates its biological properties

  2002cited by this paper
• Human neutrophil defensin and serpins form complexes and inactivate each other.

  1995cited by this paper
• On a Remarkable Bacteriolytic Element Found in Tissues and Secretions

  1922cited by this paper

• Regulatory Peptides in Asthma

  2021cites this paper