Holographic aberration correction: optimising the stiffness of an optical trap deep in the sample.

We investigate the effects of 1(st) order spherical aberration and defocus upon the stiffness of an optical trap tens of μm into the sample. We control both these aberrations with a spatial light modulator. The key to maintain optimum trap stiffness over a range of depths is a specific non-trivial combination of defocus and axial objective position. This optimisation increases the trap stiffness by up to a factor of 3 and allows trapping of 1 μm polystyrene beads up to 50 μm deep in the sample.

• Publication year

  2011

• Venue

  Optics Express

• Publication date

  2011-11-21

• Fields of study

  Materials Science, Physics, Medicine

• Identifiers
  DOI 10.1364/OE.19.024589PMID 22109488
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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