Scaling and regeneration of self-organized patterns.

Biological patterns generated during development and regeneration often scale with organism size. Some organisms, e.g., flatworms, can regenerate a rescaled body plan from tissue fragments of varying sizes. Inspired by these examples, we introduce a generalization of Turing patterns that is self-organized and self-scaling. A feedback loop involving diffusing expander molecules regulates the reaction rates of a Turing system, thereby adjusting pattern length scales proportional to system size. Our model captures essential features of body plan regeneration in flatworms as observed in experiments.

• Publication year

  2014

• Venue

  Physical Review Letters

• Publication date

  2014-11-10

• Fields of study

  Biology, Medicine, Physics, Computer Science

• Identifiers
  DOI 10.1103/PhysRevLett.114.138101arXiv 1411.2359PMID 25884138
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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