1.2 Å X-ray Structure of the Renal Potassium Channel Kv1.3 T1 Domain

No abstract is available for this paper.

• Publication year

  2013

• Venue

  The Protein Journal

• Publication date

  2013-10-11

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s10930-013-9513-2PMID 24114469
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanism of Voltage Gating in Potassium Channels

  2012cited by this paper
• Voltage‐gated potassium channels and the diversity of electrical signalling

  2012cited by this paper
• Mechanisms of closed‐state inactivation in voltage‐gated ion channels

  2011cited by this paper
• A Gating Charge Transfer Center in Voltage Sensors

  2010cited by this paper
• Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

  2010cited by this paper
• Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel

  2009cited by this paper
• Crystallization and preliminary X-ray diffraction studies of the tetramerization domain derived from the human potassium channel Kv1.3.

  2009cited by this paper
• Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

  2008cited by this paper
• A structural link between inactivation and block of a K+ channel

  2008cited by this paper
• The Neuronal Kv4 Channel Complex

  2008cited by this paper
• Zn2+-dependent Redox Switch in the Intracellular T1-T1 Interface of a Kv Channel*

  2007cited by this paper
• Phaser crystallographic software

  2007cited by this paper
• Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

  2007cited by this paper
• Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits

  2007cited by this paper
• Three-dimensional structure of the KChIP1–Kv4.3 T1 complex reveals a cross-shaped octamer

  2006cited by this paper
• Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR

  2006cited by this paper
• Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

  2006cited by this paper
• Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K+ Channel

  2006cited by this paper
• The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

  2005cited by this paper
• Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K+ Channel

  2005cited by this paper
• Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

  2005cited by this paper
• Coot: model-building tools for molecular graphics.

  2004cited by this paper
• Ion channels: Gate expectations

  2004cited by this paper
• Structure acquisition of the T1 domain of Kv1.3 during biogenesis.

  2004cited by this paper
• The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.

  2004cited by this paper
• Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cells.

  2004cited by this paper
• Cytoplasmic gatekeepers of K+-channel flux: a structural perspective.

  2004cited by this paper
• Automated structure determination of proteins by NMR spectroscopy

  2004cited by this paper
• A voltage-gated K(+) current in renal inner medullary collecting duct cells.

  2004cited by this paper
• X-ray structure of a voltage-dependent K+ channel

  2003cited by this paper
• Determining the basis of channel-tetramerization specificity by x-ray crystallography and a sequence-comparison algorithm: Family values (FamVal)

  2003cited by this paper
• The voltage-gated potassium channel subunit, Kv1.3, is expressed in epithelia.

  2003cited by this paper
• Crystal Structure of the Potassium Channel KirBac1.1 in the Closed State

  2003cited by this paper
• Crystal structure and mechanism of a calcium-gated potassium channel

  2002cited by this paper
• The voltage-gated potassium channels and their relatives

  2002cited by this paper
• Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution

  2001cited by this paper
• Controlling potassium channel activities: Interplay between the membrane and intracellular factors

  2001cited by this paper
• Impact of Transverse Relaxation Optimized Spectroscopy (TROSY) on NMR as a technique in structural biology

  2000cited by this paper
• Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.

  2000cited by this paper
• Voltage dependent activation of potassium channels is coupled to T1 domain structure

  2000cited by this paper
• The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.

  2000cited by this paper
• Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels

  1999cited by this paper
• Towards the three-dimensional structure of voltage-gated potassium channels.

  1999cited by this paper
• The moving parts of voltage-gated ion channels

  1998cited by this paper
• Structural conservation in prokaryotic and eukaryotic potassium channels.

  1998cited by this paper
• The structure of the potassium channel: molecular basis of K+ conduction and selectivity.

  1998cited by this paper
• Crystal structure of the tetramerization domain of the Shaker potassium channel

  1998cited by this paper
• Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution.

  1997cited by this paper
• Improved R-factors for diffraction data analysis in macromolecular crystallography

  1997cited by this paper
• Refinement of macromolecular structures by the maximum-likelihood method.

  1997cited by this paper
• NMR structure of inactivation gates from mammalian voltage-dependent potassium channels

  1997cited by this paper
• 1H, 13C and 15N chemical shift referencing in biomolecular NMR

  1995cited by this paper
• High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli.

  1995cited by this paper
• Potassium channels and their evolving gates

  1994cited by this paper
• The CCP4 suite: programs for protein crystallography.

  1994cited by this paper
• Long range hydrogen bond mediated effects in peptides nitrogen 15 nmr study of gramicidin s in water and organic solvents

  1984cited by this paper

• Synthesis, crystal structure, hirshfeld surface analysis, molecular docking and molecular dynamics studies of novel olanzapinium 2,5-dihydroxybenzoate as potential and active antipsychotic compound

  2022cites this paper
• Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges

  2021cites this paper
• Venom‐derived peptide inhibitors of voltage‐gated potassium channels

  2017cites this paper