Effect of intrafusal muscle mechanics on mammalian muscle spindle sensitivity

Sensitivity differences between primary and secondary endings of mammalian muscle spindles under various conditions of stretch and fusimotor activation may be due to differences in their respective mechanoelectric transducers or to mechanical properties of the intrafusal muscle supporting those endings. This study of isolated cat muscle spindles examines the strain in individual intrafusal muscle fibers resulting from stretch and fusimotor stimulation. The degree of local stretch occurring at the sensory endings under these conditions was measured. The results support the hypothesis that the sensitivities of primary and secondary endings are quite similar. They are directly related to the local stretch of the underlying muscle which may be altered by changes in muscle stress and stiffness.

• Publication year

  1985

• Venue

  Journal of Neuroscience

• Publication date

  1985-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1523/JNEUROSCI.05-07-01881.1985PMID 3160835PMCID PMC6565107
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1982cited by this paper
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  1982cited by this paper
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  1980cited by this paper
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• Small-signal analysis of response of mammalian muscle spindles with fusimotor stimulation and a comparison with large-signal responses.

  1978cited by this paper
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  1977cited by this paper
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  1976cited by this paper
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  1975cited by this paper
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  1969cited by this paper
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  1969cited by this paper
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  2005cites this paper
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  2004cites this paper
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