Membranous expressions of Lewis y and CAM-DR-related markers are independent factors of chemotherapy resistance and poor prognosis in epithelial ovarian cancer.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  American Journal of Cancer Research

• Publication date

  2015-01-15

• Fields of study

  Medicine

• Identifiers
  PMID 25973320PMCID PMC4396026
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• HE4 (WFDC2) gene overexpression promotes ovarian tumor growth

  2014cited by this paper
• Cancer statistics, 2014

  2014cited by this paper
• TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients

  2014cited by this paper
• Co-Expression of Lewis y Antigen with Human Epididymis Protein 4 in Ovarian Epithelial Carcinoma

  2013cited by this paper
• Cancer drug resistance: an evolving paradigm

  2013cited by this paper
• Cell Adhesion and Its Endocytic Regulation in Cell Migration during Neural Development and Cancer Metastasis

  2012cited by this paper
• The tumor microenvironment is a dominant force in multidrug resistance.

  2012influential reference
• In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147

  2012cited by this paper
• Epithelial ovarian cancer: focus on targeted therapy.

  2011cited by this paper
• Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance.

  2011cited by this paper
• Global cancer statistics

  2011cited by this paper
• Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I

  2011cited by this paper
• Study on the Expression and Clinical Significances of Lewis y Antigen and Integrin αv, β3 in Epithelial Ovarian Tumors

  2011cited by this paper
• Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells

  2010cited by this paper
• Enhancement of the adhesive and spreading potentials of ovarian carcinoma RMG-1 cells due to increased expression of integrin alpha5beta1 with the Lewis Y-structure on transfection of the alpha1,2-fucosyltransferase gene.

  2010cited by this paper
• Fucosylation and gastrointestinal cancer.

  2010cited by this paper
• Lewis(y) antigen stimulates the growth of ovarian cancer cells via regulation of the epidermal growth factor receptor pathway.

  2010cited by this paper
• Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

  2009cited by this paper
• RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion.

  2009cited by this paper
• Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides

  2009cited by this paper
• Loss of tight junction barrier function and its role in cancer metastasis.

  2009cited by this paper
• Interaction between CD147 and P-Glycoprotein and Their Regulation by Ubiquitination in Breast Cancer Cells

  2008cited by this paper
• Involvement of CD147 in regulation of multidrug resistance to P‐gp substrate drugs and in vitro invasion in breast cancer cells

  2007cited by this paper
• Drug resistance and the solid tumor microenvironment.

  2007cited by this paper
• Alterations in the glycolipid composition and cellular properties of ovarian carcinoma‐derived RMG‐1 cells on transfection of the α1,2‐fucosyltransferase gene

  2005cited by this paper
• Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma.

  2003cited by this paper
• Histological classification of ovarian cancer

  2003cited by this paper
• Integrins as novel drug targets for overcoming innate drug resistance.

  2002cited by this paper
• Cell adhesion is a key determinant in de novo multidrug resistance (MDR): new targets for the prevention of acquired MDR.

  2001cited by this paper
• A Proportional Hazards Model for the Subdistribution of a Competing Risk

  1999cited by this paper
• Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines.

  1999cited by this paper
• Cell Adhesion Mediated Drug Resistance (CAM-DR): Role of Integrins and Resistance to Apoptosis in Human Myeloma Cell Lines

  1999cited by this paper
• Expression of cell adhesion molecules on ovarian tumour cell lines and mesothelial cells, in relation to ovarian cancer metastasis.

  1995cited by this paper

• Delta‐like 1 homolog (DLK1) regulates cancer stemness and chemoresistance of ovarian cancer by CD44/CD133 upregulation

  2026cites this paper
• Alpha 5 integrin as a prognostic biomarker for survival in carcinomas: a systematic review

  2025influential citation
• Matrix-free microfluidic 3D biomimetic chip for identifying type I collagen on doxorubicin treated MDA-MB-231 cell

  2025cites this paper
• Integration of scRNA-seq and bulk RNA-seq to reveal the association and potential molecular mechanisms of metabolic reprogramming regulated by lactylation and chemotherapy resistance in ovarian cancer

  2025cites this paper
• A review concerning the breast cancer-related tumour microenvironment.

  2024cites this paper
• Fucosyltransferase 4 upregulates P-gp expression for chemoresistance via NF-κB signaling pathway.

  2024cites this paper
• Ovarian Cancer—Insights into Platinum Resistance and Overcoming It

  2023cites this paper
• Generation of a High-Affinity Nanobody Against CD147 for Tumor Targeting and Therapeutic Efficacy Through Conjugating Doxorubicin

  2022cites this paper
• HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways

  2022cites this paper
• Construction of miRNA‐lncRNA‐mRNA co‐expression network affecting EMT‐mediated cisplatin resistance in ovarian cancer

  2022cites this paper
• Mechanisms of Cell Adhesion Molecules in Endocrine-Related Cancers: A Concise Outlook

  2022cites this paper
• Role of BRCA Mutation and HE4 in Predicting Chemotherapy Response in Ovarian Cancer: A Retrospective Pilot Study

  2021cites this paper
• Human Epididymis Protein 4 and Lewis y Enhance Chemotherapeutic Resistance in Epithelial Ovarian Cancer Through the p38 MAPK Pathway

  2021cites this paper
• Effectiveness of human epididymis protein 4 (HE4) as predictor of response to first line platinum based chemotherapy

  2021cites this paper
• CAM-DR: Mechanisms, Roles and Clinical Application in Tumors

  2021cites this paper
• Tumor microenvironment promotes breast cancer chemoresistance

  2021cites this paper
• Big data-based identification of methylated genes associated with drug resistance and prognosis in ovarian cancer

  2020cites this paper
• Role of human epididymis protein 4 (HE4) as predictor of response to platinum based chemotherapy: a systematic review of literature

  2020cites this paper
• Gene expression profiles following active HE4 stimulation in epithelial ovarian cancer cells: microarray study and comprehensive bioinformatics analysis

  2020cites this paper
• CD44 in Ovarian Cancer Progression and Therapy Resistance—A Critical Role for STAT3

  2020cites this paper
• Cell Biology International

  2020cites this paper
• Chemotherapy Resistance in Advanced Ovarian Cancer Patients

  2019cites this paper
• The Impact of Integrin-Mediated Matrix Adhesion on Cisplatin Resistance of W1 Ovarian Cancer Cells

  2019cites this paper
• Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization

  2018cites this paper
• Clinicopathological and Prognostic Significance of Cancer Stem Cell Markers in Ovarian Cancer Patients: Evidence from 52 Studies

  2018cites this paper
• Lewis(y) antigen-mediated positive feedback loop induces and promotes chemotherapeutic resistance in ovarian cancer.

  2018cites this paper
• HE4 and eIF3a Expression Correlates with Surgical Outcome and Overall Survival in Ovarian Cancer Patients with Secondary Cytoreduction

  2018cites this paper
• HE4 level in ascites may assess the ovarian cancer chemotherapeutic effect

  2018cites this paper
• Increased HE4 mRNA Expression Correlates with High Level Of eIF3a mRNA And Better Survival in Women with Epithelial Ovarian Cancer

  2018cites this paper
• Genomic markers of ovarian adenocarcinoma and its relevancy to the effectiveness of chemotherapy

  2017cites this paper
• High expressions of BCL6 and Lewis y antigen are correlated with high tumor burden and poor prognosis in epithelial ovarian cancer

  2017cites this paper
• The prognostic role of the cancer stem cell marker CD44 in ovarian cancer: a meta-analysis

  2017cites this paper
• Prognostic role of the cancer stem cell marker CD44 in ovarian cancer: a meta-analysis.

  2016cites this paper
• Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma

  2016cites this paper
• Analysis of the gene expression profile in response to human epididymis protein 4 in epithelial ovarian cancer cells.

  2016cites this paper
• The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells

  2016cites this paper
• Molecular diagnosis and molecular profiling to detect treatment-resistant ovarian cancer

  2016cites this paper
• HE4 as a predictor of adjuvant chemotherapy resistance and survival in patients with epithelial ovarian cancer

  2016cites this paper
• Mir-200c inhibits HOTAIR expression resulting in the decrease of chemoresistance in ovarian cancer stem cells

  2016cites this paper
• The prognostic value and clinicopathological significance of CD44 expression in ovarian cancer: a meta-analysis

  2016cites this paper
• Interplay between Tumor Microenvironment and Cancer Cells

  2016cites this paper
• Gene expression profile analysis in response to α1,2-fucosyl transferase (FUT1) gene transfection in epithelial ovarian carcinoma cells

  2016influential citation
• Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis

  2015cites this paper
• Expression and Function of CD44 in Epithelial Ovarian Carcinoma

  2015cites this paper
• Overexpression of HE4 (human epididymis protein 4) enhances proliferation, invasion and metastasis of ovarian cancer

  2015cites this paper