Synthesis and Radiolabelling of Ipratropium and Tiotropium for Use as PET Ligands in the Study of Inhaled Drug Deposition

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Australian Journal of Chemistry

• Publication date

  2006-02-21

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1071/CH05303
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Pharmacokinetics of ipratropium bromide after single dose inhalation and oral and intravenous administration

  2004cited by this paper
• Radionuclide imaging technologies and their use in evaluating asthma drug deposition in the lungs.

  2003cited by this paper
• Pharmaceutical Inhalation Aerosol Technology

  2003cited by this paper
• Changes in Lung Deposition of Aerosols due to Hygroscopic Growth: A Fast SPECT Study

  2002cited by this paper
• Synthesis and nicotinic acetylcholine-binding properties of epibatidinehomologues: homoepibatidine and dihomoepibatidine

  2001cited by this paper
• Pharmacokinetics and tissue distribution of the anticholinergics tiotropium and ipratropium in the rat and dog

  2001cited by this paper
• Photochemical N-demethylation of alkaloids.

  2001cited by this paper
• The pharmacological properties of tiotropium.

  2000cited by this paper
• In Vivo Characterization of Inhaled Pharmaceuticals Using Quantitative Positron Emission Tomography

  1999cited by this paper
• Deposition of aqueous aerosol of technetium-99m diethylene triamine penta-acetic acid generated and delivered by a novel system (AERx) in healthy subjects

  1999cited by this paper
• Palladium-Catalyzed Carbonylative Coupling of Iodonium Salts with Organostannanes under Aqueous Conditions: Synthesis of Unsymmetrical Vinyl and Aromatic Ketones

  1998cited by this paper
• Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity

  1997cited by this paper
• A MEISENHEIMER REARRANGEMENT APPROACH TO BRIDGEHEAD HYDROXYLATED TROPANE ALKALOID DERIVATIVES

  1996cited by this paper
• Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease.

  1995cited by this paper
• Characterization of [3H]Ba 679 BR, a slowly dissociating muscarinic antagonist, in human lung: radioligand binding and autoradiographic mapping.

  1994cited by this paper
• Ba 679 BR, a novel long-acting anticholinergic bronchodilator.

  1993cited by this paper
• Direct labelling of ipratropium bromide aerosol and its deposition pattern in normal subjects and patients with chronic bronchitis.

  1984cited by this paper
• Quantitation of uptake of bromine-77 in the human brain

  1984cited by this paper
• Preparation of noratropine by oxidative n‐demethylation of atropine

  1983cited by this paper
• Carbon-carbon bond formation promoted by transition metal carbonyls. 19. General synthesis of tropane alkaloids via the polybromo ketone-iron carbonyl reaction

  1978cited by this paper
• Stereochemistry of tropane quaternization

  1971cited by this paper
• Acetylenics. 1. Aromatic amines containing the acetylenic triple bond.

  1970cited by this paper
• The Formation of 3,3'-Thenil in the Reaction Between 3-Thienyl-lithium and Dimethyl Oxalate at -70 degrees C.

  1969cited by this paper

• Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition

  2022cites this paper
• MegaSyn: Integrating Generative Molecular Design, Automated Analog Designer, and Synthetic Viability Prediction

  2021cites this paper
• Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections

  2016cites this paper
• Summary of Publications

  2013cites this paper
• Tropane‐Based Alkaloids as Muscarinic Antagonists for the Treatment of Asthma, Obstructive Pulmonary Disease, and Motion Sickness

  2013cites this paper
• One-pot oxidative N-demethylation of tropane alkaloids with hydrogen peroxide and a FeIII-TAML catalyst

  2012cites this paper
• Syntheses of deuterium labelled atropine and scopolamine

  2009cites this paper
• Small molecule receptors as imaging targets.

  2008cites this paper
• Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs.

  2008cites this paper