Biomarkers in the Prevention and Treatment of Atherosclerosis: Need, Validation, and Future

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Pharmacological Reviews

• Publication date

  2007-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1124/pr.59.1.1PMID 17329547
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID TrialNissen SE, for the ASTEROID Investigators (Cleveland Clinic Found, Ohio; Brigham and Women's Hosp, Boston; Harvard Med School, Boston; et al) JAMA 295:1556–1565, 2006§

  2007cited by this paper
• European guidelines on cardiovascular disease prevention in clinical practice: executive summary.

  2007cited by this paper
• Effect of ACAT inhibition on the progression of coronary atherosclerosis.

  2006cited by this paper
• Workshop on CV prevention with a focus on metabolic syndrome and surrogate markers. Taskforce 1 of the Cardiovascular Round Table, European Society of Cardiology: Executive Summary Report.

  2006cited by this paper
• Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)--can C-reactive protein be used to target statin therapy in primary prevention?

  2006cited by this paper
• You need hands

  2006cited by this paper
• C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients.

  2006cited by this paper
• Surrogate endpoints: A basis for a rational approach

  2006influential reference
• The Effect of Including C-Reactive Protein in Cardiovascular Risk Prediction Models for Women

  2006cited by this paper
• Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.

  2006influential reference
• Valsartan, Blood Pressure Reduction, and C-Reactive Protein: Primary Report of the Val-MARC Trial

  2006cited by this paper
• C-reactive protein levels and outcomes after statin therapy.

  2005cited by this paper
• Inflammation, atherosclerosis, and coronary artery disease.

  2005cited by this paper
• C-Reactive Protein and the 10-Year Incidence of Coronary Heart Disease in Older Men and Women: The Cardiovascular Health Study

  2005cited by this paper
• High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey.

  2005cited by this paper
• Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease.

  2005cited by this paper
• Intensive versus moderate lipid lowering with statins after acute coronary syndromes.

  2004cited by this paper
• A trial design for evaluation of empiric programming of implantable cardioverter defibrillators to improve patient management

  2004influential reference
• Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial.

  2004cited by this paper
• Early Statin Treatment in Patients With Acute Coronary Syndrome: Demonstration of the Beneficial Effect on Atherosclerotic Lesions by Serial Volumetric Intravascular Ultrasound Analysis During Half a Year After Coronary Event: The ESTABLISH Study

  2004cited by this paper
• Challenge and Opportunity on the Critical Path to New Medical Products

  2004cited by this paper
• C-Reactive Protein Modulates Risk Prediction Based on the Framingham Score: Implications for Future Risk Assessment: Results From a Large Cohort Study in Southern Germany

  2004cited by this paper
• Relationship Between Cardiovascular Risk as Predicted by Established Risk Scores Versus Plaque Progression as Measured by Serial Intravascular Ultrasound in Left Main Coronary Arteries

  2004cited by this paper
• C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease.

  2004cited by this paper
• Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions

  2004cited by this paper
• Burden-of-disease estimates.

  2003cited by this paper
• Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association.

  2003cited by this paper
• Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial.

  2003cited by this paper
• Prevalence of conventional risk factors in patients with coronary heart disease.

  2003cited by this paper
• European guidelines on cardiovascular disease prevention in clinical practice; Third Joint Task Force of European and other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of eight societies and by invited experts)

  2003cited by this paper
• European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice.

  2003cited by this paper
• Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project.

  2003cited by this paper
• MARKERS OF INFLAMMATION AND CARDIOVASCULAR DISEASE: APPLICATION TO CLINICAL AND PUBLIC HEALTH PRACTICE: A STATEMENT FOR HEALTHCARE PROFESSIONALS FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION AND THE AMERICAN HEART ASSOCIATION

  2003cited by this paper
• Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events*

  2002cited by this paper
• Intima–media thickness: a new tool for diagnosis and treatment of cardiovascular risk

  2002cited by this paper
• Inflammatory bio‐markers and cardiovascular risk prediction

  2002cited by this paper
• Simple Scoring Scheme for Calculating the Risk of Acute Coronary Events Based on the 10-Year Follow-Up of the Prospective Cardiovascular Münster (PROCAM) Study

  2002influential reference
• Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.

  2002cited by this paper
• Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST).

  2002cited by this paper
• ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: A Randomized Trial Comparing the Effects of Atorvastatin and Pravastatin on Carotid Intima Medial Thickness

  2002cited by this paper
• High Prevalence of Coronary Atherosclerosis in Asymptomatic Teenagers and Young Adults: Evidence From Intravascular Ultrasound

  2001cited by this paper
• Use of Intravascular Ultrasound to Compare Effects of Different Strategies of Lipid-Lowering Therapy on Plaque Volume and Composition in Patients With Coronary Artery Disease

  2001cited by this paper
• Low-Dose Metoprolol CR/XL and Fluvastatin Slow Progression of Carotid Intima-Media Thickness: Main Results From the &bgr;-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS)

  2001cited by this paper
• Correlation between high frequency intravascular ultrasound and histomorphology in human coronary arteries

  2001cited by this paper
• The New England Journal

  2000cited by this paper
• Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study.

  2000cited by this paper
• C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.

  2000influential reference
• Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group.

  1999cited by this paper
• Lower-extremity arteriosclerosis as a reflection of a systemic process: implications for concomitant coronary and carotid disease.

  1999cited by this paper
• The Role of Carotid Arterial Intima-Media Thickness in Predicting Clinical Coronary Events

  1998influential reference
• B-mode ultrasound assessment of pravastatin treatment effect on carotid and femoral artery walls and its correlations with coronary arteriographic findings: a report of the Regression Growth Evaluation Statin Study (REGRESS).

  1998cited by this paper
• Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study.

  1997influential reference
• Inflammation, aspirin, and the risk of cardiovascular disease.

  1997cited by this paper
• Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993.

  1997cited by this paper
• Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS]).

  1997cited by this paper
• Intravascular ultrasound analysis of reduction in progression of coronary narrowing by treatment with pravastatin.

  1997cited by this paper
• Risk-reduction therapy: the challenge to change. Presented at the 68th scientific sessions of the American Heart Association November 13, 1995 Anaheim, California.

  1996cited by this paper
• Pravastatin reduces carotid intima-media thickness progression in an asymptomatic hypercholesterolemic mediterranean population: the Carotid Atherosclerosis Italian Ultrasound Study.

  1996cited by this paper
• Pravastatin, Lipids, and Atherosclerosis in the Carotid Arteries (PLAC-II)

  1995cited by this paper
• Kuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL lowering on atherosclerotic progression in carotid and femoral arteries.

  1995cited by this paper
• Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels. The Regression Growth Evaluation Statin Study (REGRESS).

  1995cited by this paper
• Lipid-lowering interventions in angiographic trials.

  1995cited by this paper
• Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC I): reduction in atherosclerosis progression and clinical events. PLAC I investigation.

  1995cited by this paper
• Effect of simvastatin on coronary atheroma: the Multicentre Anti-Atheroma Study (MAAS)

  1994cited by this paper
• Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.

  1994cited by this paper
• Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.

  1994cited by this paper
• Retardation and arrest of progression or regression of coronary artery disease: a review.

  1993cited by this paper
• Lipid Lowering and Plaque Regression New Insights Into Prevention of Plaque Disruption and Clinical Events in Coronary Disease

  1993cited by this paper
• Beneficial Effects of Colestipol‐Niacin Therapy on the Common Carotid Artery. Two‐ and Four‐Year Reduction of Intima‐Media Thickness Measured by Ultrasound

  1993cited by this paper
• Coronary Angiographic Changes with Lovastatin Therapy: The Monitored Atherosclerosis Regression Study (MARS)

  1993cited by this paper
• Isolated systolic hypertension and vessel wall thickness of the carotid artery. The Rotterdam Elderly Study.

  1993cited by this paper
• Arterial wall thickness in familial hypercholesterolemia. Ultrasound measurement of intima-media thickness in the common carotid artery.

  1992cited by this paper
• Isolated systolic hypertension and subclinical cardiovascular disease in the elderly. Initial findings from the Cardiovascular Health Study.

  1992cited by this paper
• Relation of extent of extracranial carotid artery atherosclerosis as measured by B-mode ultrasound to the extent of coronary atherosclerosis.

  1991cited by this paper
• Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC study.

  1991cited by this paper
• Risk factors for early carotid atherosclerosis in middle-aged French women.

  1991cited by this paper
• An updated coronary risk profile. A statement for health professionals.

  1991influential reference
• Determinants of carotid intima‐media thickness: a population‐based ultrasonography study in Eastern Finnish men

  1991cited by this paper
• Histopathologic Validation of Angioscopy and Intravascular Ultrasound

  1991cited by this paper
• Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.

  1990cited by this paper
• Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts.

  1987cited by this paper
• Relationship Between Arterial Disease in Different Sites

  1962cited by this paper
• Relationship between arterial disease in different sites. A study of the aorta and coronary, carotid, and iliac arteries.

  1962cited by this paper
• Serologic tests for inflammation; serum complement, c-reactive protein and erythrocyte sedimentation rate in myocardial infarction.

  1956cited by this paper
• THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD

  1941cited by this paper
• THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD

  1941cited by this paper
• SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS

  1930cited by this paper

• Biomarkers as Surrogate Endpoints in Drug Development: Finding Their Right Place.

  2025cites this paper
• A study of carotid intima media thickness in patients with rheumatoid arthritis and its correlation with acute phase reactants and disease activity

  2024cites this paper
• Non-calcified active atherosclerosis plaque detection with 18F-NaF and 18F-FDG PET/CT dynamic imaging

  2023cites this paper
• Label‐free atherosclerosis diagnosis through a blood drop of apolipoprotein E knockout mouse model using surface‐enhanced Raman spectroscopy validated by machine learning algorithm

  2023cites this paper
• Identification of Molecular Subtypes and Key Genes of Atherosclerosis Through Gene Expression Profiles

  2021cites this paper
• Meta-analysis of epigenome-wide association studies of carotid intima-media thickness

  2021cites this paper
• Coupling of 18F-NaF and 18F-FDG PET/CT Dynamic Imaging for the Detection of Arterial Inflammation

  2021cites this paper
• Quantitative Analysis in PET Imaging

  2021cites this paper
• Cardiovascular/stroke risk predictive calculators: a comparison between statistical and machine learning models.

  2020cites this paper
• Low-Cost Office-Based Cardiovascular Risk Stratification Using Machine Learning and Focused Carotid Ultrasound in an Asian-Indian Cohort

  2020cites this paper
• Index of opportunity for natural selection among the Idu Mishmi of Dibang Valley district, Arunachal Pradesh

  2020cites this paper
• Does the Carotid Bulb Offer a Better 10-Year CVD/Stroke Risk Assessment Compared to the Common Carotid Artery? A 1516 Ultrasound Scan Study

  2020cites this paper
• Carotid Intima-Media Thickness and the Risk of First Stroke in Patients With Hypertension

  2020cites this paper
• Assessment of artery calcification in atherosclerosis with dynamic 18F-FDG-PET/CT imaging in elderly subjects

  2019cites this paper
• A low-cost machine learning-based cardiovascular/stroke risk assessment system: integration of conventional factors with image phenotypes.

  2019cites this paper
• Interested in publishing with us ? Contact book

  2018cites this paper
• 4 Atherosclerosis and Antihyperlipidemic Agents

  2017influential citation
• Hypolipidemic and antioxidant effects of the Methanolic stem bark extract of Anacardium occidentale Linn. In triton-X 100 induced hyperlipidemic rats

  2017influential citation
• The Role of Noninvasive Imaging for Detection High Risk Patients with Subclinical Atherosclerosis

  2016cites this paper
• Cardiovascular Diseases: Can Herb-Based Antioxidant and Anti-Inflammatory Functional Products Be a Solution?

  2016cites this paper
• Correlation of carotid intimal media thickness with activity and duration of Rheumatoid arthritis using carotid Doppler Ultrasonography

  2016cites this paper
• Carotid Intima-media Thickness Measurements: Relations with Atherosclerosis, Risk of Cardiovascular Disease and Application in Randomized Controlled Trials

  2016cites this paper
• Analysis of gene expression profile identifies potential biomarkers for atherosclerosis

  2016cites this paper
• Correlates of Incident Cognitive Impairment in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study

  2015cites this paper
• Novel Inflammatory Markers in Hyperlipidemia: Clinical Implications.

  2015cites this paper
• Carotid Intima-Medial Thickness in Diagnosis and Prognosis of Atherosclerotic Risk in Obstructive Sleep Apnea Patients

  2015cites this paper
• Correlation of Intima Media Thickness ( As a Marker of Atherosclerosis ) With Activity and Duration of Rheumatoid Arthritis Using Carotid Ultrasound

  2015cites this paper
• Microfluidic devices for mechanical characterization and manipulation of monocytes

  2015cites this paper
• Thromboxane Prostaglandin Receptor Antagonist and Carotid Atherosclerosis Progression in Patients With Cerebrovascular Disease of Ischemic Origin: A Randomized Controlled Trial

  2014cites this paper
• Biomarkers for osteoarthritis: current position and steps towards further validation.

  2014cites this paper
• Type 2 diabetes and cardiovascular diseases: How biomarkers can support more tailored based approaches?

  2014cites this paper
• Synthesis and haemolytic activity of novel salts made of nicotine alkaloids and bile acids.

  2014cites this paper
• Site-directed immobilization of antibody using EDC-NHS-activated protein A on a bimetallic-based surface plasmon resonance chip

  2014cites this paper
• Microwave-assisted synthesis of surface-enhanced Raman scattering nanoprobes for cellular sensing.

  2014cites this paper
• Assessment of inflammation in large arteries with 18F-FDG-PET in elderly

  2013cites this paper
• Atherosclerotic Coronary Artery Disease

  2013cites this paper
• Determination of site-specific carotid-intima media thickness: common –carotid artery and carotid bifurcation in hypercholesterolemia patients

  2013cites this paper
• Screening for subclinical atherosclerosis by noninvasive methods in asymptomatic patients with risk factors

  2013cites this paper
• Cardiovascular biomarkers and surrogate end points: key initiatives and clinical trial challenges

  2012cites this paper
• Lessons from the past and promises for the future for carotid intima-media thickness.

  2012cites this paper
• Galectins testing: new promises for the diagnosis and risk stratification of chronic diseases?

  2012cites this paper
• Noninvasive cardiovascular imaging in rheumatoid arthritis: current modalities and the emerging role of magnetic resonance and positron emission tomography imaging.

  2012cites this paper
• Rate of change in carotid intima–media thickness and vascular events: meta-analyses can not solve all the issues. A point of view

  2012cites this paper
• Antibody Phage Display Assisted Identification of Junction Plakoglobin as a Potential Biomarker for Atherosclerosis

  2012cites this paper
• Factor VIII deficiency does not protect against atherosclerosis

  2012cites this paper
• Atherosclerosis and Antihyperlipidemic Agents

  2012influential citation
• Drug Therapy and Follow-Up

  2011influential citation
• Algorithms to measure carotid intima–media thickness in trials: a comparison of reproducibility, rate of progression and treatment effect

  2011cites this paper
• The use of plaque score measurements to assess changes in atherosclerotic plaque burden induced by lipid-lowering therapy over time: the METEOR study.

  2011cites this paper
• Effect of number of ultrasound examinations on the assessment of carotid intima–media thickness changes over time: the example of the METEOR study

  2011cites this paper
• From joint anatomy to clinical outcomes in osteoarthritis and cartilage repair: summary of the fifth annual osteoarthritis imaging workshop.

  2011cites this paper
• Carotid Intima-Media Thickness Measurement: A Suitable Alternative for Cardiovascular Risk?

  2011cites this paper
• Markers for Subclinical Atherosclerosis in Women with Polycystic Ovary Syndrome and Controls

  2011cites this paper
• Validation of Surrogate Outcomes: Application to Biomarkers of Atherosclerosis

  2011cites this paper
• Associations between cardiovascular risk factors, hyper- and hypocoagulability

  2011cites this paper
• Atherosclerosis Drug Development in Jeopardy: The Need for Predictive Biomarkers of Treatment Response

  2011cites this paper
• Overview of the pathogenesis of atherosclerosis and gender differences in CAD

  2010cites this paper
• Optimizing clinical trial design for assessing the efficacy of functional foods.

  2010cites this paper
• A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials.

  2010cites this paper
• Atherosclerosis and sex hormones: current concepts.

  2010cites this paper
• Raised Plasma Urotensin II in Type 2 Diabetes Patients Is Associated With the Metabolic Syndrome Phenotype

  2010cites this paper
• Imaging of atherosclerosis: carotid intima-media thickness.

  2010cites this paper
• Ultrasound protocols to measure carotid intima-media thickness in trials; comparison of reproducibility, rate of progression, and effect of intervention in subjects with familial hypercholesterolemia and subjects with mixed dyslipidemia

  2010cites this paper
• Relation of common carotid intima-media thickness with left ventricular mass caused by shared risk factors for hypertrophy.

  2009influential citation
• Intensive lipid lowering may reduce progression of carotid atherosclerosis within 12 months of treatment: the METEOR study

  2009cites this paper
• Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdala.

  2009cites this paper
• Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study

  2009cites this paper
• Models to study atherosclerosis: a mechanistic insight.

  2009cites this paper
• Reassessing the validity of surrogate markers of drug efficacy in the treatment of coronary artery disease.

  2009cites this paper
• Clinical relevance of predictive physiologically based pharmacokinetic methods

  2008cites this paper
• Use of Nebivolol For the Treatment of Endothelial Dysfunction in Patients With Hypertension: The EDEN Registry

  2008cites this paper
• Form to function: current and future roles for atherosclerosis imaging in drug development

  2008cites this paper
• Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice

  2008cites this paper
• Carotid intimomedial thickness--a non-invasive index of vascular health.

  2008cites this paper
• Individual Assessment of Arteriosclerosis by Empiric Clinical Profiling

  2007cites this paper
• The continuing complexities of high-density lipoprotein metabolism in drug discovery and development

  2007cites this paper
• Atherosclerotic plaque development: Disease Pathogenesis and emerging treatment options

  year unknowncites this paper