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Antimicrobial Activity Against Hospital‐related Pathogens of Dual Layer CuO/TiO2 Coatings Prepared by CVD

H. Foster,D. W. Sheel,P. Evans,P. Sheel,Sajnu Varghese,Souad O. Elfakhri,John L. Hodgkinson,H. M. Yates

Published 2012 in Chemical Vapor Deposition

ABSTRACT

Photocatalytically active films of TiO2/CuO grown by atmospheric pressure thermal (APT)CVD are investigated for activity against multiple antibiotic-resistant pathogens namely, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, vancomycin-resistant enterococci (VRE), and a recent isolate of methicillin-resistant Staphylococcus aureus (MRSA), that have been shown to persist in the hospital environment. The bacteria are killed by UVA irradiation of the photocatalyst with a>5 log kill within 4–6 h except for the MRSA where a 2–3 log kill is obtained after 6 h increasing to >5 log after 24 h. There is antimicrobial activity in the dark which is enhanced by irradiation with fluorescent light. There is also activity at 5 8C under UVA, but activity is lower when fluorescent light is used for illumination.

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