A distinct trans-Golgi network subcompartment for sorting of synaptic and granule proteins in neurons and neuroendocrine cells

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Cell Science

• Publication date

  2011-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/jcs.076372PMID 21321327PMCID PMC3039018
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• How peptide hormone vesicles are transported to the secretion site for exocytosis.

  2008cited by this paper
• Dense-core secretory granule biogenesis.

  2006influential reference
• Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature

  2006cited by this paper
• A Direct Interaction between Cdc42 and Vesicle-associated Membrane Protein 2 Regulates SNARE-dependent Insulin Exocytosis*

  2005cited by this paper
• Protein Kinase A Affects Trafficking of the Vesicular Monoamine Transporters in PC12 Cells

  2004influential reference
• The Cholinergic Neuronal Phenotype in Alzheimer's Disease

  2004cited by this paper
• Dynamics of Secretory Membrane Trafficking

  2004influential reference
• Vesicular Localization and Activity-Dependent Trafficking of Presynaptic Choline Transporters

  2003cited by this paper
• Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts.

  2003cited by this paper
• Synaptophysin I controls the targeting of VAMP2/synaptobrevin II to synaptic vesicles.

  2003cited by this paper
• Dynamics of immature secretory granules: role of cytoskeletal elements during transport, cortical restriction, and F-actin-dependent tethering.

  2001cited by this paper
• A Glut4‐Vesicle Marker Protein, Insulin‐Responsive Aminopeptidase, is Localized in a Novel Vesicular Compartment in PC12 Cells

  2001cited by this paper
• Chromogranin A, an "on/off" switch controlling dense-core secretory granule biogenesis.

  2001cited by this paper
• Trafficking of green fluorescent protein tagged‐vesicular acetylcholine transporter to varicosities in a cholinergic cell line

  2001cited by this paper
• Biogenesis of Regulated Exocytotic Carriers in Neuroendocrine Cells

  2000influential reference
• Lipid Raft Association of Carboxypeptidase E Is Necessary for Its Function as a Regulated Secretory Pathway Sorting Receptor*

  2000cited by this paper
• The cholinergic neuronal phenotype in alzheimer′s disease

  2000cited by this paper
• A Phosphorylation Site Regulates Sorting of the Vesicular Acetylcholine Transporter to Dense Core Vesicles

  2000cited by this paper
• The vesicular monoamine transporter VMAT2 and vesicular acetylcholine transporter VAChT are sorted to separate vesicle populations in PC12 cells.

  1998cited by this paper
• Sorting and storage during secretory granule biogenesis: looking backward and looking forward.

  1998cited by this paper
• The Cholinergic Gene Locus

  1998cited by this paper
• Vesiculation and sorting from PC12-derived endosomes in vitro.

  1998cited by this paper
• Synaptic-like Microvesicles of Neuroendocrine Cells Originate from a Novel Compartment That Is Continuous with the Plasma Membrane and Devoid of Transferrin Receptor

  1997cited by this paper
• Target-independent cholinergic differentiation in the rat sympathetic nervous system.

  1997cited by this paper
• Vesicular monoamine transporter‐2: Immunogold localization in striatal axons and terminals

  1997cited by this paper
• Differential Localization of Vesicular Acetylcholine and Monoamine Transporters in PC12 Cells but Not CHO Cells

  1997influential reference
• The production of post-Golgi vesicles requires a protein kinase C-like molecule, but not its phosphorylating activity

  1996influential reference
• Differential distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system.

  1996cited by this paper
• Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles.

  1996influential reference
• Endocytosis of VAMP is facilitated by a synaptic vesicle targeting signal

  1996cited by this paper
• The vesicular monoamine transporter 2 is present in small synaptic vesicles and preferentially localizes to large dense core vesicles in rat solitary tract nuclei.

  1995cited by this paper
• Biogenesis of synaptic vesicles in vitro

  1995influential reference
• Pan-neuronal expression of chromogranin A in rat nervous system.

  1994cited by this paper
• Differential effects of temperature blockade on the proteolytic processing of three secretory granule-associated proteins.

  1994cited by this paper
• Acetylcholine transport, storage, and release.

  1993cited by this paper
• Synaptic vesicle proteins and early endosomes in cultured hippocampal neurons: differential effects of Brefeldin A in axon and dendrites

  1993cited by this paper
• Selective storage of acetylcholine, but not catecholamines, in neuroendocrine synaptic-like microvesicles of early endosomal origin.

  1993cited by this paper
• Chromogranin A, a soluble synaptic vesicle protein, is found in cortical neurons other than previously defined peptidergic neurons in the human neocortex.

  1993cited by this paper
• Protein targeting via the "constitutive-like" secretory pathway in isolated pancreatic islets: passive sorting in the immature granule compartment

  1992cited by this paper
• Secretory granule and synaptic vesicle formation.

  1991influential reference
• Biogenesis of synaptic vesicle-like structures in a pheochromocytoma cell line PC-12

  1990cited by this paper
• Pathways to regulated exocytosis in neurons.

  1990influential reference
• Heterogeneity of presynaptic muscarinic receptors involved in modulation of transmitter release.

  1989cited by this paper
• Characterization, by Size, Density, Osmotic Fragility, and Immunoaffinity, of Acetylcholine‐ and Vasoactive Intestinal Polypeptide‐Containing Storage Particles from Myenteric Neurones of the Guinea‐Pig

  1989cited by this paper
• Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane

  1985influential reference
• Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles.

  1985influential reference
• Choline and acetylcholine metabolism in PC12 secretory cells.

  1981influential reference
• Synthesis, storage and release of acetylcholine by a noradrenergic pheochromocytoma cell line

  1977influential reference
• Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

  1976influential reference

• Siamese Twins: The Multimodular Mechanisms of Golgi Maturation and Glycan Synthesis Are Coupled at Their Core.

  2026cites this paper
• Dense-core vesicles contain exosomes in secretory cells.

  2025cites this paper
• Systematic and comprehensive analysis of major localizations of alpha-dystroglycan-specific modifying enzymes.

  2025cites this paper
• SNARE Proteins Mediate α-Synuclein Secretion via Multiple Vesicular Pathways

  2021cites this paper
• Systematic Comparison of Vesicular Targeting Signals Leads to the Development of Genetically Encoded Vesicular Fluorescent Zn2+ and pH Sensors.

  2020cites this paper
• Biogenesis of large dense core vesicles in mouse chromaffin cells

  2020influential citation
• TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

  2020cites this paper
• Biogenesis of large dense core vesicles and molecular mechanisms of dead-end docking in mouse chromaffin cells

  2019cites this paper
• Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells

  2019cites this paper
• Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins

  2018cites this paper
• New approaches for solving old problems in neuronal protein trafficking

  2018cites this paper
• UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes

  2017cites this paper
• Characterization of functional μ opioid receptor turnover in rat locus coeruleus: an electrophysiological and immunocytochemical study

  2017cites this paper
• Retrograde trafficking of VMAT2 and its role in protein stability in non-neuronal cells

  2016cites this paper
• Orientation and organization of the presynaptic active zone protein Bassoon: from the Golgi to the synapse

  2016cites this paper
• Membrane Trafficking Mechanisms: Exocytosis and Endocytosis in Dendrites

  2016cites this paper
• The Conserved VPS-50 Protein Functions in Dense-Core Vesicle Maturation and Acidification and Controls Animal Behavior.

  2016cites this paper
• Poster Presentations

  2015cites this paper
• Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals

  2015cites this paper
• Molecular Underpinnings of Synaptic Vesicle Pool Heterogeneity

  2015cites this paper
• AVP modulation of the vestibular nucleus via V1b receptors potentially contributes to the development of motion sickness in rat

  2015cites this paper
• The Redistribution of Drosophila Vesicular Monoamine Transporter Mutants from Synaptic Vesicles to Large Dense-Core Vesicles Impairs Amine-Dependent Behaviors

  2014influential citation
• Molecular mechanisms of GLUT4 regulation in adipocytes.

  2014cites this paper
• Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors

  2014cites this paper
• Cellular regulation of glucose uptake by glucose transporter GLUT4.

  2014cites this paper
• Prions disturb post-Golgi trafficking of membrane proteins

  2013cites this paper
• Copper modulates the large dense core vesicle secretory pathway in PC12 cells.

  2013cites this paper
• Annexin A1 Complex Mediates Oxytocin Vesicle Transport

  2013cites this paper
• Cellular mechanisms for the biogenesis and transport of synaptic and dense-core vesicles.

  2012influential citation
• Crosstalk and Integration of Membrane Trafficking Pathways

  2012cites this paper
• Phosphatidylinositol Bisphosphate Mediated Sorting of Secretory Granule Cargo

  2012cites this paper
• Gestational nicotine exposure regulates expression of AMPA and NMDA receptors and their signaling apparatus in developing and adult rat hippocampus.

  2011cites this paper