Tumor DNA in cerebral spinal fluid reflects clinical course in a patient with melanoma leptomeningeal brain metastases

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Neuro-Oncology

• Publication date

  2016-03-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11060-016-2081-5PMID 26961773PMCID PMC5412509
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

  2015cited by this paper
• Brain tumor mutations detected in cerebral spinal fluid.

  2015cited by this paper
• Complete Cytologic Remission of V600E BRAF-Mutant Melanoma-Associated Leptomeningeal Carcinomatosis Upon Treatment With Dabrafenib.

  2015cited by this paper
• Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

  2014cited by this paper
• Trimmomatic: a flexible trimmer for Illumina sequence data

  2014cited by this paper
• Vemurafenib in the French temporary authorization for use metastatic melanoma cohort: a single-centre trial

  2014cited by this paper
• Unusual acute and delayed skin reactions during and after whole-brain radiotherapy in combination with the BRAF inhibitor vemurafenib

  2014cited by this paper
• Current views on regulation and function of plasticity-related genes (PRGs/LPPRs) in the brain.

  2013cited by this paper
• Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

  2013cited by this paper
• Circulating tumour cells and cell-free DNA as tools for managing breast cancer

  2013cited by this paper
• Early Detection of BCR-ABL Fusion Gene of Cerebrospinal Fluid (CSF) by RT-PCR in Relapsed Acute Lymphoblastic Leukemia with Philadelphia Chromosome

  2012cited by this paper
• Treatment of Leptomeningeal Spread of NSCLC: A Continuing Challenge

  2012cited by this paper
• Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib.

  2012cited by this paper
• Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

  2012cited by this paper
• Abstract 5370: PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

  2011cited by this paper
• Improved survival with vemurafenib in melanoma with BRAF V600E mutation.

  2011cited by this paper
• Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50

  2011cited by this paper
• "Pulsatile" high-dose weekly erlotinib for CNS metastases from EGFR mutant non-small cell lung cancer.

  2011cited by this paper
• ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.

  2011cited by this paper
• The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.

  2010cited by this paper
• Plasma cell‐free DNA in ovarian cancer

  2010cited by this paper
• Leptomeningeal metastasis

  2010cited by this paper
• ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

  2010cited by this paper
• BRafV600E cooperates with Pten silencing to elicit metastatic melanoma

  2009cited by this paper
• Circulating cell-free DNA in plasma/serum of lung cancer patients as a potential screening and prognostic tool.

  2006cited by this paper
• Cell‐free DNA and RNA in Plasma as a New Molecular Marker for Prostate and Breast Cancer

  2006cited by this paper
• Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.

  2004cited by this paper
• Chapter 65 – Leptomeningeal Metastasis

  2003cited by this paper
• Early detection of leptomeningeal metastasis by PCR examination of tumor-derived K-ras DNA in cerebrospinal fluid.

  2000cited by this paper
• Diagnosis and treatment of leptomeningeal metastases from solid tumors: Experience with 90 patients

  1982cited by this paper
• BIOINFORMATICS ORIGINAL PAPER

  year unknowncited by this paper

• Detection of Circulating Tumor DNA in Liquid Biopsy: Current Techniques and Potential Applications in Melanoma

  2025cites this paper
• Adaptive cohort design and LAT1 expression scale: study protocol for a Phase 2a trial of QBS72S in breast cancer brain metastases

  2025cites this paper
• Circulating Cell-Free Tumor DNA-Based Liquid Biopsy of Cerebrospinal Fluid in Retinoblastoma

  2025cites this paper
• 脑脊液循环肿瘤DNA在非小细胞肺癌柔脑膜转移中的临床应用进展

  2024cites this paper
• Personalized therapy guided by longitudinal liquid biopsies for treatment of leptomeningeal disease from lung adenocarcinoma: A case report

  2024cites this paper
• Clinical applications of cerebrospinal fluid liquid biopsies in central nervous system tumors

  2024cites this paper
• Quantification of cerebrospinal fluid tumor DNA in lung cancer patients with suspected leptomeningeal carcinomatosis

  2024cites this paper
• Cerebral spinal fluid analyses and therapeutic implications for leptomeningeal metastatic disease

  2024cites this paper
• Detection of cell‐free tumor DNA in cerebrospinal fluid as a diagnostic biomarker for leptomeningeal melanoma metastasis: A case series

  2024cites this paper
• Extracellular vesicles and melanoma: New perspectives on tumor microenvironment and metastasis

  2023cites this paper
• The Value of Cell-Free Circulating DNA Profiling in Patients with Skin Diseases.

  2023cites this paper
• The coming of age of liquid biopsy in neuro-oncology

  2023cites this paper
• Diagnostic and Therapeutic Updates in Leptomeningeal Disease

  2023cites this paper
• A Review on the Efficacy and Safety of Intrathecal Administration of Novel Medications for Leptomeningeal Metastases in Solid Cancers.

  2023cites this paper
• Meta-analysis of commonly mutated genes in leptomeningeal carcinomatosis

  2023cites this paper
• Exploring the role of cerebrospinal fluid as analyte in neurologic disorders

  2023cites this paper
• Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases.

  2023cites this paper
• Leptomeningeal disease in melanoma: An update on the developments in pathophysiology and clinical care

  2023cites this paper
• Promising and Minimally Invasive Biomarkers: Targeting Melanoma

  2023cites this paper
• Circulating tumour DNA — looking beyond the blood

  2022cites this paper
• Case report: Real-world experience using a personalized cancer-specific circulating tumor DNA assay in different metastatic melanoma scenarios

  2022cites this paper
• Tapping into the genome: the role of CSF ctDNA liquid biopsy in glioma

  2022cites this paper
• cfDNA-Based NGS IG Analysis in Lymphoma.

  2022cites this paper
• Circulating Tumour DNA in Melanoma—Clinic Ready?

  2022cites this paper
• Clinical experience of cerebrospinal fluid-based liquid biopsy demonstrates superiority of cell free DNA over cell pellet genomic DNA for molecular profiling.

  2021cites this paper
• Evaluating Infectious, Neoplastic, Immunological, and Degenerative Diseases of the Central Nervous System with Cerebrospinal Fluid-Based Next-Generation Sequencing

  2021cites this paper
• Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases

  2021cites this paper
• Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma

  2021cites this paper
• Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid

  2021cites this paper
• Less‐invasive diagnosis of disseminated epithelioid glioblastoma harboring BRAF V600E mutation by cerebrospinal fluid analysis—A case report

  2021cites this paper
• Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

  2021cites this paper
• Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy

  2021influential citation
• Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators

  2021cites this paper
• ddPCR-based detection of circulating tumour DNA from paediatric high grade and diffuse midline glioma patients

  2021cites this paper
• Leptomeningeal disease from melanoma-Poor prognosis despite new therapeutic modalities.

  2021cites this paper
• Leptomeningeal Carcinomatosis

  2021cites this paper
• Current and future trends in non–small cell lung cancer biomarker testing: The American experience

  2020cites this paper
• Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy

  2020influential citation
• Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions

  2020cites this paper
• Clinical Applications of Cerebrospinal Fluid Circulating Tumor DNA as a Liquid Biopsy for Central Nervous System Tumors

  2020cites this paper
• Clinical Applications of Cerebrospinal Fluid Circulating Tumor DNA as a Liquid Biopsy for Central Nervous System Tumors

  2020cites this paper
• 'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

  2020cites this paper
• Erdheim-Chester disease: a case treated with IFN-α monitored using plasma and urine cell-free DNA.

  2020cites this paper
• Cancer Genomics in Precision Oncology: Applications, Challenges, and Prospects

  2020cites this paper
• Evaluation of cell-free DNA as a diagnostic marker in cerebrospinal fluid of dogs.

  2020cites this paper
• Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.

  2020cites this paper
• Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.

  2020cites this paper
• Diagnostic value of circulating tumor DNA in molecular characterization of glioma

  2020cites this paper
• Leptomeningeal Carcinomatosis: Molecular Landscape, Current Management, and Emerging Therapies.

  2020cites this paper
• Creative and Innovative Methods and Techniques for the Challenges in the Management of Adult Craniopharyngioma.

  2020cites this paper
• ctDNA as a cancer biomarker: A broad overview.

  2020cites this paper
• Ventricular Cerebrospinal Fluid Sampling in Pediatric Diffuse Midline Glioma Patients: Institutional Experience and Review of the Literature

  2020cites this paper
• Technical and Methodological Aspects of Cell-Free Nucleic Acids Analyzes

  2020cites this paper
• Metastasis to the Central Nervous System.

  2020cites this paper
• Liquid biopsy in central nervous system tumors: the potential roles of circulating miRNA and exosomes.

  2020cites this paper
• Review: Peering through a keyhole: liquid biopsy in primary and metastatic central nervous system tumours

  2019cites this paper
• Clinical, Imaging, and CSF Cytological Presentation of Leptomeningeal Metastases from Solid Non-CNS Primary Tumors

  2019cites this paper
• Liquid Biopsy Diagnosis of CNS Metastases

  2019cites this paper
• Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications

  2019cites this paper
• The potential of cerebrospinal fluid-based liquid biopsy approaches in CNS tumors.

  2019cites this paper
• Cytological-negative pleural effusion can be an alternative liquid biopsy media for detection of EGFR mutation in NSCLC patients.

  2019cites this paper
• Clinical Characteristics, Molecular Phenotyping, and Management of Isolated Adrenal Metastases From Lung Cancer.

  2019cites this paper
• Detection of Circulating Tumor DNA with a Single-Molecule Sequencing Analysis Validated for Targeted and Immunotherapy Selection

  2019cites this paper
• Peripheral biomarkers for pediatric brain tumors: current advancements and future challenges

  2019cites this paper
• Retrospective review of metastatic melanoma patients with leptomeningeal disease treated with intrathecal interleukin-2

  2018cites this paper
• Molecular Cytopathology: Final Thoughts and Future Directions

  2018cites this paper
• Circulating tumour DNA, microRNA and metabolites in cerebrospinal fluid as biomarkers for central nervous system malignancies

  2018cites this paper
• Locus‐specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma

  2018cites this paper
• Next-Generation Novel Noninvasive Cancer Molecular Diagnostics Platforms Beyond Tissues.

  2018cites this paper
• CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response

  2018cites this paper
• Implementation of cell-free tumor DNA sequencing from the cerebrospinal fluid to guide treatment in a patient with primary leptomeningeal melanoma: A case report.

  2018cites this paper
• The Utility of Liquid Biopsy in Central Nervous System Malignancies

  2018cites this paper
• Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease

  2018cites this paper
• Leptomeningeal metastasis.

  2018cites this paper
• Genetic profiling of cell-free DNA from cerebrospinal fluid: opening the barrier to leptomeningeal metastasis in EGFR-mutant NSCLC.

  2018cites this paper
• Potential Molecular Signatures Predictive of Lung Cancer Brain Metastasis

  2018cites this paper
• Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluid

  2018cites this paper
• Neoplastic meningitis in solid tumors: from diagnosis to personalized treatments

  2018cites this paper
• Cell-Free DNA: An Overview of Sample Types and Isolation Procedures.

  2018cites this paper
• EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours.

  2017cites this paper
• Detection of BRAFV600K mutant tumor-derived DNA in the pleural effusion from a patient with metastatic melanoma

  2017cites this paper
• Current and Emerging Applications of Droplet Digital PCR in Oncology

  2017cites this paper
• A pilot study on the use of cerebrospinal fluid cell-free DNA in intramedullary spinal ependymoma

  2017cites this paper
• Guidelines for diagnosis , treatment and follow-up of patients with leptomeningeal metastasis from solid tumours †

  2017cites this paper
• Fluorescence Lifetime Imaging Microscopy, a Novel Diagnostic Tool for Metastatic Cell Detection in the Cerebrospinal Fluid of Children with Medulloblastoma

  2017cites this paper
• Recurrently Mutated Genes Differ between Leptomeningeal and Solid Lung Cancer Brain Metastases

  2017influential citation
• Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

  2017cites this paper
• Circulating tumour DNA (ctDNA) as a liquid biopsy for melanoma.

  2017cites this paper
• Leptomeningeal metastases of solid cancer.

  2016cites this paper
• LONG-TERM SURVIVAL IN METASTATIC MELANOMA PATIENTS WITH LEPTOMENINGEAL DISEASE TREATED WITH INTRATHECAL INTERLEUKIN-2

  2016influential citation
• Brain Metastasis: Clinical Implications of Branched Evolution.

  2016cites this paper