Inhibition of Epstein-Barr Virus (EBV) Reactivation by Short Interfering RNAs Targeting p38 Mitogen-Activated Protein Kinase or c-myc in EBV-Positive Epithelial Cells

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Virology

• Publication date

  2004-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.78.21.11798-11806.2004PMID 15479821PMCID PMC523256
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003cited by this paper
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  2002cited by this paper
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• 12-O-tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-kappaB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase.

  2001influential reference
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999influential reference
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
• How cells respond to interferons.

  1998cited by this paper
• Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

  1998cited by this paper
• HIV-Tat protein activates c-Jun N-terminal kinase and activator protein-1.

  1998cited by this paper
• Transgene-induced gene silencing in plants.

  1998cited by this paper
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  1998cited by this paper
• Tat protein induces self-perpetuating permissivity for productive HIV-1 infection.

  1997cited by this paper
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  1996cited by this paper
• Lymphoblastoid cells transfected with c‐myc: Downregulation of EBV‐lytic antigens and impaired response of autologousCD4+ T cells in vitro

  1996cited by this paper
• Characterization of transforming growth factor-beta 1 induced apoptosis in normal human B cells and lymphoma B cell lines.

  1995cited by this paper
• Characterization of seven newly established nasopharyngeal carcinoma cell lines.

  1993cited by this paper
• Epstein-Barr virus-associated gastric adenocarcinoma.

  1992cited by this paper
• Epstein–Barr virus infection and replication in a human epithelial cell system

  1992cited by this paper
• Early events in Epstein-Barr virus infection of human B lymphocytes.

  1991cited by this paper
• Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1

  1990cited by this paper
• Expression of normal and translocated c‐myc alleles in Burkitt's lymphoma cells: evidence for different regulation.

  1989cited by this paper
• Multiple mechanisms regulate c‐myc gene expression during normal T cell activation.

  1988cited by this paper
• Drastically increased expression of MYC and FOS protooncogenes during in vitro differentiation of chronic lymphocytic leukemia cells.

  1987cited by this paper
• [The role of protein kinase C in cell surface signal transduction and tumor promotion].

  1986cited by this paper
• trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment

  1986cited by this paper
• Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

  1985cited by this paper
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  1984cited by this paper
• Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.

  1983cited by this paper
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  1978cited by this paper
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  1970cited by this paper
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  year unknowncited by this paper

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