Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Neurophysiology

• Publication date

  1999-02-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/JN.1999.81.2.413PMID 10036248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1993influential reference
• Physiological properties and morphological characteristics of cutaneous and mucosal mechanical nociceptive neurons with A‐δ peripheral axons in the trigeminal ganglia of crotaline snakes

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• Blockade by calcium antagonists of chemical excitation and sensitization of polymodal nociceptors in the cat's cornea.

  1992influential reference
• Slow inactivation of tetrodotoxin-insensitive Na+ channels in neurons of rat dorsal root ganglia

  1992cited by this paper
• Comparison of two types of Na+ currents with low-voltage-activated T-type Ca2+ current in newborn rat dorsal root ganglia

  1992cited by this paper
• Three types of sodium channels in adult rat dorsal root ganglion neurons.

  1992influential reference
• Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor.

  1992cited by this paper
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  1991cited by this paper
• Mechanically insensitive afferents (MIAs) in cutaneous nerves of monkey

  1990cited by this paper
• Termination patterns of identified group II and III afferent fibres from deep tissues in the spinal cord of the cat.

  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1984cited by this paper
• Calcium- and sodium-dependent action potentials of mouse spinal cord and dorsal root ganglion neurons in cell culture.

  1982cited by this paper
• Synaptic complexes formed by functionally defined primary afferent units with fine myelinated fibers

  1982cited by this paper
• Primary afferent units from the hairy skin of the rat hind limb.

  1982cited by this paper
• Differential Sensitivity of Fast and Slow Fibers in Mammalian Nerve II. Margin of Safety for Nerve Transmission

  1982cited by this paper
• Ionic currents in the somatic membrane of rat dorsal root ganglion neurons-I. Sodium currents.

  1981cited by this paper
• Responses dependent on alkaline earth cations (Ca, Sr, Ba) in dorsal root ganglion cells of the adult mouse.

  1980cited by this paper
• Spike potentials and membrane properties of dorsal root ganglion cells in pigeons

  1980cited by this paper
• Differential Sensitivities of Mammalian Nerve Fibers to Local Anesthetic Agents

  1980cited by this paper
• Studies on sensory neurons of the mouse with intracellular-recording and horseradish peroxidase-injection techniques.

  1979cited by this paper
• Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers

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  1978cited by this paper
• Tetrodotoxin sensitivity and Ca component of action potentials of mouse dorsal root ganglion cells cultured in vitro.

  1978cited by this paper
• Propagating calcium spikes in an axon of Aplysia.

  1978cited by this paper
• The action potential of chick dorsal root ganglion neurones maintained in cell culture.

  1977cited by this paper
• Ionic determinants of excitability in cultured mouse dorsal root ganglion and spinal cord cells.

  1977cited by this paper
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  1972cited by this paper
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  1968cited by this paper
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