Branching, capping, and severing in dynamic actin structures.

Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A formulation of these processes is presented and analyzed to study steady-state network morphology. In bulk, we identify several scaling regimes in severing and branching protein concentrations and find that the coupling between severing and branching is optimally exploited for conditions in vivo. Near the leading edge, we find qualitative agreement with the in vivo morphology.

• Publication year

  2007

• Venue

  Physical Review Letters

• Publication date

  2007-03-15

• Fields of study

  Biology, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1103/PhysRevLett.99.058103arXiv cond-mat/0703409PMID 17930797
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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