The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity

The mechanisms and determinants preserving lysosomal membrane stability are unclear. Here, Li et al. show that the lysosomal membrane protein SCAV-3, the Caenorhabditis elegans homologue of human LIMP-2, is a key regulator of lysosome integrity and normal adult lifespan.

• Publication year

  2016

• Venue

  Journal of Cell Biology

• Publication date

  2016-10-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201602090PMID 27810910PMCID 5084646
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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