New Benzoyl Glucosides and Cytotoxic Pterosin Sesquiterpenes from Pteris ensiformis Burm.

Three new compounds: 2R,3R-pterosin L 3-O-β-D-glucopyranoside (1), β-D-xylopyranosyl(1→2)-7-O-benzoyl-β-D-glucopyranoside (2) and 4-O-benzoyl-β-D-xylo-pyranosyl(1→2)-7-O-benzoyl-β-D-glucopyranoside (3), together with nine known compounds, were isolated from the ethyl acetate extract of Pteris ensiformis. 5-[2-Hydroxyethylidene]-2(5H)-furanone (4), which had been synthesized, was isolated from natural sources for the first time. The structures of all isolated compounds were determined on the basis of mass and spectroscopic evidence. Compound 1 and pterosin B (5) show cytotoxicity against HL 60 cells (human leukemia) with the IC50 values of 3.7 and 8.7 μg/mL, respectively.

• Publication year

  2008

• Venue

  Molecules

• Publication date

  2008-02-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.3390/molecules13020255PMID 18305416PMCID 6245482
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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