Cell surface targeting of the Melanocortin 5 Receptor (MC5R) requires serine-rich terminal motifs.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Biochimica et biophysica acta. Molecular cell research

• Publication date

  2017-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.bbamcr.2017.04.004PMID 28396017
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors

  2016cited by this paper
• Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane*

  2015cited by this paper
• Intracellular signaling mechanisms of the melanocortin receptors: current state of the art

  2014cited by this paper
• Structural determinants regulating cell surface targeting of melanocortin receptors.

  2013cited by this paper
• Exposure of MC4R to agonist in the endoplasmic reticulum stabilizes an active conformation of the receptor that does not desensitize

  2013cited by this paper
• Alpha-MSH signalling via melanocortin 5 receptor promotes lipolysis and impairs re-esterification in adipocytes.

  2013cited by this paper
• Molecular characterization of human melanocortin-5 receptor ligand-receptor interaction.

  2013cited by this paper
• Melanocortin 5 receptor signaling and internalization: role of MAPK/ERK pathway and β-arrestins 1/2.

  2012cited by this paper
• Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations.

  2012cited by this paper
• The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants.

  2011cited by this paper
• Identification of Three Novel Genetic Variants in the Melanocortin‐3 Receptor of Obese Children

  2011cited by this paper
• N‐glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role

  2011cited by this paper
• Mahoganoid and Mahogany Mutations Rectify the Obesity of the Yellow Mouse by Effects on Endosomal Traffic of MC4R Protein*

  2011cited by this paper
• Pharmacological Chaperones Restore Function to MC4R Mutants Responsible for Severe Early-Onset Obesity

  2010cited by this paper
• Obesity-linked variants of melanocortin-4 receptor are misfolded in the endoplasmic reticulum and can be rescued to the cell surface by a chemical chaperone.

  2010cited by this paper
• Role of asparagine-linked glycosylation in cell surface expression and function of the human adrenocorticotropin receptor (melanocortin 2 receptor) in 293/FRT cells.

  2010cited by this paper
• Loss of the C terminus of melanocortin receptor 2 (MC2R) results in impaired cell surface expression and ACTH insensitivity.

  2010cited by this paper
• Opposite Effects of the Melanocortin-2 (MC2) Receptor Accessory Protein MRAP on MC2 and MC5 Receptor Dimerization and Trafficking*

  2009cited by this paper
• Structural insights on melanocortin 5 receptor targeting to cell surface

  2009cited by this paper
• Melanocortin 5 receptor activates ERK1/2 through a PI3K-regulated signaling mechanism.

  2009cited by this paper
• MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

  2009cited by this paper
• Peripheral Effect of α-Melanocyte-stimulating Hormone on Fatty Acid Oxidation in Skeletal Muscle*

  2007cited by this paper
• Peripheral effect of alpha-melanocyte-stimulating hormone on fatty acid oxidation in skeletal muscle.

  2007cited by this paper
• Regulation of G protein-coupled receptor export trafficking.

  2007cited by this paper
• Constitutive Traffic of Melanocortin-4 Receptor in Neuro2A Cells and Immortalized Hypothalamic Neurons*

  2007cited by this paper
• Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cells.

  2007cited by this paper
• Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers

  2007cited by this paper
• Regulation of Anterograde Transport of α2-Adrenergic Receptors by the N Termini at Multiple Intracellular Compartments*

  2006cited by this paper
• Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk.

  2005cited by this paper
• Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2

  2005cited by this paper
• The melanocortin-1 receptor carboxyl terminal pentapeptide is essential for MC1R function and expression on the cell surface.

  2005cited by this paper
• Cell Surface Expression of the Melanocortin-4 Receptor Is Dependent on a C-terminal Di-isoleucine Sequence at Codons 316/317*

  2003cited by this paper
• Deletions of the N‐terminal regions of the human melanocortin receptors

  1997cited by this paper
• Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides.

  1997cited by this paper
• Identification of ligand binding residues in extracellular loops of the melanocortin 1 receptor.

  1996cited by this paper
• Protein Folding and Misfolding: Mechanisms and Consequences Pharmacological Chaperones Increase the Cell-surface Expression of Intracellularly Retained Mutants of the Melanocortin 4 Receptor with Unique Rescuing Efficacy Profiles

  year unknowncited by this paper

• Melanocortin/MC5R axis regulates the proliferation of hematopoietic stem cells in mice after ionizing radiation injury

  2023cites this paper
• Differential barcoding of opioid receptors trafficking

  2021influential citation
• Strategies for Site‐Specific Labeling of Receptor Proteins on the Surfaces of Living Cells by Using Genetically Encoded Peptide Tags

  2021cites this paper
• Conserved C‐terminal motifs in odorant receptors instruct their cell surface expression and cAMP signaling

  2020cites this paper
• Identification and characterization of the melanocortin 1 receptor gene (MC1R) in hypermelanistic Chinese tongue sole (Cynoglossus semilaevis)

  2020cites this paper
• Mechanisms of the anterograde trafficking of GPCRs: Regulation of AT1R transport by interacting proteins and motifs

  2018cites this paper
• The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

  2017cites this paper