Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2016-02-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.1600251113PMID 26929355PMCID PMC4801305
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Palmitoylethanolamide in CNS health and disease.

  2014cited by this paper
• Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1G93A Transgenic Mice and Evaluation of a Sativex®‐like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis

  2014cited by this paper
• The changing scene of amyotrophic lateral sclerosis

  2013cited by this paper
• Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset

  2013cited by this paper
• Understanding ALS: new therapeutic approaches

  2013cited by this paper
• Riluzole blocks human muscle acetylcholine receptors

  2012influential reference
• Amyotrophic lateral sclerosis treatment with ultramicronized palmitoylethanolamide: a case report.

  2012cited by this paper
• Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease

  2012cited by this paper
• Clinical neurophysiology in ALS.

  2011cited by this paper
• The diagnosis of Amyotrophic lateral sclerosis in 2010.

  2011cited by this paper
• Physiological characterization of human muscle acetylcholine receptors from ALS patients

  2011influential reference
• Analysis of Qpcr Data by Converting Exponentially Related CT Values into Linearly Related X0 Values

  2010cited by this paper
• The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis.

  2010cited by this paper
• The endocannabinoid system: its roles in energy balance and potential as a target for obesity treatment.

  2010cited by this paper
• The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments.

  2009cited by this paper
• Microtransplantation of ligand-gated receptor-channels from fresh or frozen nervous tissue into Xenopus oocytes: a potent tool for expanding functional information.

  2009cited by this paper
• Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models.

  2009influential reference
• Neuroscience

  2008cited by this paper
• The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle‐specific nicotinic acetylcholine receptor

  2008cited by this paper
• The RIN: an RNA integrity number for assigning integrity values to RNA measurements

  2006cited by this paper
• Peripheral Nerve Diseases

  2006cited by this paper
• Receptor-independent effects of endocannabinoids on ion channels.

  2006cited by this paper
• Microtransplantation of neurotransmitter receptors from cells to Xenopus oocyte membranes: new procedure for ion channel studies.

  2006cited by this paper
• BMC Molecular Biology BioMed Central

  2006influential reference
• Interpretative strategies for lung function tests

  2005cited by this paper
• General considerations for lung function testing

  2005cited by this paper
• Standardisation of spirometry

  2005cited by this paper
• Regulation of Motoneuron Excitability via Motor Endplate Acetylcholine Receptor Activation

  2005cited by this paper
• The Endogenous Cannabinoid Anandamide Inhibits α7 Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes

  2003cited by this paper
• Motoneuron Survival Is Enhanced in the Absence of Neuromuscular Junction Formation in Embryos

  2001cited by this paper
• Reduction of Neuromuscular Activity Is Required for the Rescue of Motoneurons from Naturally Occurring Cell Death by Nicotinic-Blocking Agents

  2000cited by this paper
• The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III).

  1999cited by this paper
• Standardization of Spirometry, 1994 Update. American Thoracic Society.

  1995cited by this paper
• El escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis

  1994cited by this paper
• El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic

  1994cited by this paper
• Lung volumes and forced ventilatory flows

  1993cited by this paper
• Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society.

  1993cited by this paper
• Neural factors regulate AChR subunit mRNAs at rat neuromuscular synapses

  1991cited by this paper
• Diagnosis of amyotrophic lateral sclerosis

  1991cited by this paper
• On the effect of muscle activity on the end‐plate membrane in denervated mouse muscle.

  1989cited by this paper
• AIDS TO THE EXAMINATION OF THE PERIPHERAL NERVOUS SYSTEM.

  1988cited by this paper
• Standardization of spirometry.

  1987cited by this paper
• Standardization of spirometry.

  1987cited by this paper
• The motor end‐plate fine structure and ultrastructural localization of acetylcholine receptors in amyotrophic lateral sclerosis

  1984cited by this paper
• Further observations on the distribution of acetylcholine‐reactive sites in skeletal muscle

  1964cited by this paper
• Junctional and extra‐junctional acetylcholine receptors in skeletal muscle fibres

  1960cited by this paper

• Phase 2 study of palmitoylethanolamide combined with luteoline in frontotemporal dementia patients

  2025cites this paper
• Mechanisms of neuromuscular junction dysfunction in amyotrophic lateral sclerosis

  2025cites this paper
• Aberrant evoked calcium signaling and nAChR cluster morphology in a SOD1 D90A hiPSC-derived neuromuscular model

  2024cites this paper
• The Effect of Palmitoylethanolamide (PEA) on Skeletal Muscle Hypertrophy, Strength, and Power in Response to Resistance Training in Healthy Active Adults: A Double-Blind Randomized Control Trial

  2024cites this paper
• Quantitative evaluation of factors influencing the 3 Hz repetitive nerve stimulation test in patients with amyotrophic lateral sclerosis

  2024cites this paper
• Analysis of the neuromuscular deficits caused by STAM1 deficiency

  2024cites this paper
• Circulating endocannabinoidome signatures of disease activity in amyotrophic lateral sclerosis

  2024cites this paper
• Palmitoylethanolamide supplementation for human health: A state-of-the-art systematic review of Randomized Controlled Trials in patient populations

  2024influential citation
• Muscle Involvement in Amyotrophic Lateral Sclerosis: Understanding the Pathogenesis and Advancing Therapeutics

  2023cites this paper
• Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery

  2023cites this paper
• The Xenopus Oocyte: A Tool for Membrane Biology

  2023cites this paper
• Pathomechanistic Networks of Motor System Injury in Amyotrophic Lateral Sclerosis

  2023cites this paper
• Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models

  2023cites this paper
• Enhancing Stability and Albumin Binding Efficiency of α-Conotoxin GI through Fatty Acid Modification.

  2023cites this paper
• Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABA B -ergic activity and cortical plasticity in long COVID-19 syndrome

  2022cites this paper
• Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABA B -ergic activity and cortical plasticity in long COVID-19 syndrome

  2022cites this paper
• Classical and Unexpected Effects of Ultra-Micronized PEA in Neuromuscular Function

  2022cites this paper
• Neuromuscular Junction Dysfunction in Amyotrophic Lateral Sclerosis

  2022cites this paper
• Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome

  2022cites this paper
• The “www” of Xenopus laevis Oocytes: The Why, When, What of Xenopus laevis Oocytes in Membrane Transporters Research

  2022cites this paper
• Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double‐blind, placebo‐controlled trial

  2022cites this paper
• Therapeutic Targets in Amyotrophic Lateral Sclerosis: Focus on Ion Channels and Skeletal Muscle

  2022cites this paper
• Synaptic Effects of Palmitoylethanolamide in Neurodegenerative Disorders

  2022cites this paper
• Effects of Palmitoylethanolamide on Neurodegenerative Diseases: A Review from Rodents to Humans

  2022cites this paper
• Decoding Amyotrophic Lateral Sclerosis: A Systems Biology Approach

  2022cites this paper
• Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABA B -ergic activity and cortical plasticity in long COVID-19 syndrome

  2022cites this paper
• Ricardo Miledi. 15 September 1927—18 December 2017

  2021cites this paper
• Targeting the CB2 receptor and other endocannabinoid elements to delay disease progression in amyotrophic lateral sclerosis

  2021cites this paper
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  2021cites this paper
• Overview of stem cells therapy in amyotrophic lateral sclerosis

  2021cites this paper
• Skeletal Muscle in ALS: An Unappreciated Therapeutic Opportunity?

  2021cites this paper
• Coexistence of myasthenia gravis and amyotrophic lateral sclerosis in a Bosnian male: an unusual clinical presentation

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Creatine Kinase and Progression Rate in Amyotrophic Lateral Sclerosis

  2020cites this paper
• Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS.

  2020influential citation
• Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models.

  2020cites this paper
• Endocannabinoids and related lipids in serum from patients with amyotrophic lateral sclerosis

  2020cites this paper
• Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options

  2019cites this paper
• Cannabinoids and the expanded endocannabinoid system in neurological disorders

  2019cites this paper
• Short-Term Ultramicronized Palmitoylethanolamide Therapy in Patients with Myasthenia Gravis: a Pilot Study to Possible Future Implications of Treatment.

  2019cites this paper
• Neuromuscular magnetic stimulation counteracts muscle decline in ALS patients: results of a randomized, double-blind, controlled study

  2019cites this paper
• Oligodendrocyte precursor cells as a therapeutic target for demyelinating diseases.

  2019cites this paper
• Role of N-Acylethanolamines in the Neuroinflammation: Ultramicronized Palmitoylethanolamide in the Relief of Chronic Pain and Neurodegenerative DiseasesRole of N-Acylethanolamines in the Neuroinflammation: Ultramicronized Palmitoylethanolamide in the Relief of Chronic Pain and Neurodegenerative Dise

  2019cites this paper
• Mitochondrial defect in muscle precedes neuromuscular junction degeneration and motor neuron death in CHCHD10S59L/+ mouse

  2019cites this paper
• An Inflammation-Centric View of Neurological Disease: Beyond the Neuron

  2018cites this paper
• Neurodegenerative diseases: model organisms, pathology and autophagy

  2018cites this paper
• Neuromuscular Junction Dismantling in Amyotrophic Lateral Sclerosis

  2017cites this paper
• Potential therapeutic targets for ALS: MIR206, MIR208b and MIR499 are modulated during disease progression in the skeletal muscle of patients

  2017cites this paper
• The Endocannabinoid System and Chronic Disease

  2017cites this paper
• Editorial. Advancement in brain-machine interfaces for patients with tetraplegia: neurosurgical perspective.

  2017cites this paper
• The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations

  2017influential citation
• Systematic review of neuroprotective actions of the ECP in the HT-22 neuronal line subjected to hypoxia and reoxygenation

  year unknowncites this paper
• Palmitoylethanolamide as an emerging therapy for neurodegenerative diseases

  year unknowncites this paper