Urotensin-II: a novel systemic hypertensive factor in the cat

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  2004-02-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00210-004-0873-1PMID 14985938
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Urotensin II Acts Centrally to Increase Epinephrine and ACTH Release and Cause Potent Inotropic and Chronotropic Actions

  2003cited by this paper
• Central cardiovascular action of urotensin II in conscious rats

  2003cited by this paper
• Human urotensin-II as a novel cardiovascular target: 'heart' of the matter or simply a fishy 'tail'?

  2003cited by this paper
• Urotensin II is a nitric oxide-dependent vasodilator and natriuretic peptide in the rat kidney.

  2003cited by this paper
• Deletion of the UT receptor gene results in the selective loss of urotensin‐II contractile activity in aortae isolated from UT receptor knockout mice

  2003cited by this paper
• A Comparison of Cerebrospinal Fluid and Plasma Urotensin II Concentrations in Normotensive and Hypertensive Patients Undergoing Urological Surgery During Spinal Anesthesia: A Pilot Study

  2003cited by this paper
• Contraction of isolated guinea-pig ileum by urotensin II via activation of ganglionic cholinergic neurons and acetylcholine release.

  2003cited by this paper
• Urotensin II evokes potent vasoconstriction in humans in vivo

  2002cited by this paper
• Congestive heart failure and expression of myocardial urotensin II.

  2002cited by this paper
• No effect on central or peripheral blood pressure of systemic urotensin II infusion in humans.

  2002cited by this paper
• Plasma urotensin II in heart failure.

  2002cited by this paper
• Effects of human urotensin II in isolated vessels of various species; comparison with other vasoactive agents

  2002cited by this paper
• Molecular and pharmacological characterization of genes encoding urotensin‐II peptides and their cognate G‐protein‐coupled receptors from the mouse and monkey

  2002cited by this paper
• High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man.

  2002cited by this paper
• Comparison of the contractile responses of human coronary bypass grafts and monkey arteries to human urotensin‐II

  2001cited by this paper
• Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues

  2001cited by this paper
• Depressor and regionally‐selective vasodilator effects of human and rat urotensin II in conscious rats

  2001cited by this paper
• Cardiostimulant effects of urotensin‐II in human heart in vitro

  2001cited by this paper
• Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries.

  2001cited by this paper
• Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey

  2000cited by this paper
• Contractile responses to human urotensin‐II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat

  2000cited by this paper
• Orphan‐receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin‐1

  2000cited by this paper
• Human urotensin II mediates vasoconstriction via an increase in inositol phosphates.

  2000cited by this paper
• Human urotensin‐II is an endothelium‐dependent vasodilator in rat small arteries

  2000cited by this paper
• Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

  1999cited by this paper
• Cloning, sequence analysis and tissue distribution of the mouse and rat urotensin II precursors

  1999cited by this paper
• Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord.

  1998cited by this paper
• Guide for the Care and Use of Laboratory Animals

  1996cited by this paper
• Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes.

  1980cited by this paper
• Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

  1977cited by this paper

• Urotensin II system in chronic kidney disease

  2024cites this paper
• Potential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated Comorbidities

  2020cites this paper
• Effect of Different Peptides

  2015cites this paper
• Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease

  2015cites this paper
• International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, Urotensin II–Related Peptide, and Their Receptor: From Structure to Function

  2015cites this paper
• The Importence of Urotensin and Urotensin Receptors in Cardiovascular System

  2014cites this paper
• A closer look at the role of urotensin II in the metabolic syndrome

  2012cites this paper
• Genetic and Pharmacological Manipulation of Urotensin II Ameliorate the Metabolic and Atherosclerosis Sequalae in Mice

  2012cites this paper
• Urotensin II in the Pathogenesis of Atherosclerosis in Cholesterol Fed Rats

  2011cites this paper
• The Role of Translational Medicine and Predictive Biomarkers in the Development of Novel, Innovative Treatments for the Management of Chronic Heart Failure: A Pharmaceutical Industry Perspective

  2010cites this paper
• GSK1562590, a slowly dissociating urotensin‐II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo

  2010cites this paper
• Suche, Reinigung und Identifizierung eines Urotensin II metabolisierenden Enzyms

  2010cites this paper
• Human urotensin II promotes hypertension and atherosclerotic cardiovascular diseases.

  2009cites this paper
• The role of urotensin II in the metabolic syndrome.

  2008cites this paper
• Cardiorenovascular effects of urotensin II and the relevance of the UT receptor.

  2008cites this paper
• Role of urotensin II in atherosclerotic cardiovascular diseases.

  2008cites this paper
• Immunocytochemical localization of the urotensin-II receptor, UT, to rat and human tissues: relevance to function.

  2008cites this paper
• Development of potent and selective small-molecule human Urotensin-II antagonists.

  2008cites this paper
• Chronic urotensin II infusion enhances macrophage foam cell formation and atherosclerosis in apolipoprotein E-knockout mice

  2008cites this paper
• Aminomethylpiperazines as selective urotensin antagonists.

  2008cites this paper
• Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

  2008cites this paper
• Urotensin‐II Induces Ear Flushing in Rats

  2007cites this paper
• Therapeutic potential of blockade of the Urotensin II system in systemic hypertension

  2007cites this paper
• RESEARCH PAPER Urotensin-II Induces Ear Flushing in Rats

  2007cites this paper
• Enhancement of vascular smooth muscle cell migration by urotensin II

  2006cites this paper
• The in vivo effects of human urotensin II in the rabbit and rat pulmonary circulation: effects of experimental pulmonary hypertension.

  2006cites this paper
• Cell and tissue responses of a range of Urotensin II analogs at cloned and native urotensin II receptors. Evidence for coupling promiscuity

  2006cites this paper
• The role of urotensin II in cardiovascular and renal physiology and diseases

  2006cites this paper
• Exercise urotensin II dynamics in myocardial infarction survivors with and without hypertension.

  2006cites this paper
• Human Urotensin II as a Link between Hypertension and Coronary Artery Disease

  2006cites this paper
• The peptidic urotensin‐II receptor ligand GSK248451 possesses less intrinsic activity than the low‐efficacy partial agonists SB‐710411 and urantide in native mammalian tissues and recombinant cell systems

  2006influential citation
• Non-peptidic urotensin-II receptor modulators

  2006cites this paper
• Urotensin II and the Circulatory System

  2005cites this paper
• Effect of exogenous urotensin-II on vascular tone in skin microcirculation of patients with essential hypertension.

  2005cites this paper
• Cloning and pharmacological characterization of the cat urotensin-II receptor (UT).

  2005cites this paper
• Aminoalkoxybenzyl pyrrolidines as novel human urotensin-II receptor antagonists.

  2005cites this paper
• Urotensin II: Its Function in Health and Its Role in Disease

  2005influential citation
• Nonpeptidic urotensin‐II receptor antagonists I: in vitro pharmacological characterization of SB‐706375

  2005cites this paper
• Inhibitory effects of putative peptidic urotensin-II receptor antagonists on urotensin-II-induced contraction of cat isolated respiratory smooth muscle.

  2005cites this paper
• Urotensin II-induced hypotensive responses in Wistar-Kyoto (Wky) and spontaneously hypertensive (Shr) rats.

  2005cites this paper
• Urotensin II stimulates plasma extravasation in mice via UT receptor activation

  2004cites this paper
• Cardiovascular actions of human urotensin II—considerations for hypertension

  2004influential citation
• Emerging roles of urotensin-II in cardiovascular disease.

  2004cites this paper