Austin, dehydroaustin and other metabolites from Penicillium brasilianum

A culture of P. brasilianum, isolated from soil collected at the Serra do Cipo National Park, in Minas Gerais State (Brazil), was grown for 25 days on a dextrose-peptone-salts medium. The corresponding ethylacetate extract was column chromatographed and four compounds were isolated: austin, dehydroaustin, D-mannitol and penicillic acid. This is, in the best of our knowledge, the first time that the meroterpenes austin and dehydroaustin have been isolated from this species. Activity of the extract and isolated compounds was tested against six bacteria and for acetylcholinesterase inhibition. Penicillic acid showed high activity in both tests.

• Publication year

  2010

• Venue

  Química Nova

• Publication date

  Unknown publication date

• Fields of study

  Biology, Chemistry, Environmental Science

• Identifiers
  DOI 10.1590/S0100-40422010000500007
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

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