Lifting the nebula: novel insights into skeletal muscle contractility.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Physiology

• Publication date

  2010-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/physiol.00016.2010PMID 20940435
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2).

  2010cited by this paper
• Differential splicing of the large sarcomeric protein nebulin during skeletal muscle development.

  2010cited by this paper
• Nebulin plays a direct role in promoting strong actin‐myosin interactions

  2009influential reference
• Nebulin Alters Cross-bridge Cycling Kinetics and Increases Thin Filament Activation

  2009cited by this paper
• Peripheral muscle dysfunction in idiopathic pulmonary arterial hypertension

  2009cited by this paper
• Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.

  2009cited by this paper
• A nebulin ruler does not dictate thin filament lengths.

  2009cited by this paper
• Reduced thin filament length in nebulin-knockout skeletal muscle alters isometric contractile properties.

  2009cited by this paper
• A myopathy-linked desmin mutation perturbs striated muscle actin filament architecture.

  2008cited by this paper
• Disuse-induced Preferential Loss of the Giant Protein Titin Depresses Muscle Performance via Abnormal Sarcomeric Organization

  2008cited by this paper
• Thin filament length regulation in striated muscle sarcomeres: pointed-end dynamics go beyond a nebulin ruler.

  2008cited by this paper
• Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin‐free skeletal muscle

  2008cited by this paper
• Review focus series: sarcomeric proteins as key elements in integrated control of cardiac function.

  2007cited by this paper
• Nebulin regulates thin filament length, contractility, and Z‐disk structure in vivo

  2006cited by this paper
• Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle

  2006influential reference
• Nebulin regulates the assembly and lengths of the thin filaments in striated muscle

  2005cited by this paper
• ReviewCellular Motility Driven by Assembly and Disassembly of Actin Filaments to decipher

  2003cited by this paper
• Nebulin: the nebulous, multifunctional giant of striated muscle.

  2003cited by this paper
• Cellular motility driven by assembly and disassembly of actin filaments.

  2003cited by this paper
• Interactions between Nebulin-like Motifs and Thin Filament Regulatory Proteins*

  2003cited by this paper
• Actin binding proteins: regulation of cytoskeletal microfilaments.

  2003cited by this paper
• Tropomodulins: life at the slow end.

  2003cited by this paper
• Nebulin mutations in autosomal recessive nemaline myopathy: an update.

  2002cited by this paper
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  2002cited by this paper
• Molecular dissection of the interaction of desmin with the C-terminal region of nebulin.

  2002cited by this paper
• Each actin subunit has three nebulin binding sites: implications for steric blocking.

  2002cited by this paper
• Evidence for increased myofibrillar mobility in desmin-null mouse skeletal muscle.

  2002influential reference
• The N-terminal End of Nebulin Interacts with Tropomodulin at the Pointed Ends of the Thin Filaments*

  2001cited by this paper
• Regulation of contraction in striated muscle.

  2000cited by this paper
• Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy.

  1999cited by this paper
• Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs.

  1998cited by this paper
• Defining actin filament length in striated muscle: rulers and caps or dynamic stability?

  1998cited by this paper
• Nebulette: a 107 kD nebulin-like protein in cardiac muscle.

  1995cited by this paper
• The complete primary structure of human nebulin and its correlation to muscle structure.

  1995cited by this paper
• Calmodulin-sensitive interaction of human nebulin fragments with actin and myosin.

  1994cited by this paper
• Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb

  1994cited by this paper
• Effect of thin filament length on the force-sarcomere length relation of skeletal muscle.

  1991cited by this paper
• Cloning, expression, and protein interaction of human nebulin fragments composed of varying numbers of sequence modules.

  1991cited by this paper
• Evidence that nebulin is a protein‐ruler in muscle thin filaments

  1991cited by this paper
• Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile

  1991cited by this paper
• Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction.

  1988cited by this paper
• Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line

  1988cited by this paper
• Proposed Mechanism of Force Generation in Striated Muscle

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• Micro‐ and nano‐tomography analysis of mouse soleus muscle using radiation

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  2017cites this paper
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  2017cites this paper
• Morphological and Functional Aspects of Human Skeletal Muscle

  2016cites this paper
• Mutation‐specific effects on thin filament length in thin filament myopathy

  2016cites this paper
• Nebulin, a multi-functional giant

  2016cites this paper
• Effects of aging, exercise, and disease on force transfer in skeletal muscle.

  2015cites this paper
• Pathogenetic mechanisms and genotype-phenotype correlations in nemaline myopathies and related disorders caused by mutations in tropomyosin genes and nebulin

  2014cites this paper
• Skeletal Muscle: A Brief Review of Structure and Function

  2014influential citation
• The role of Calpain 3 in sheep skeletal muscle growth and post-mortem meat quality

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• Muscle fatigue and muscle weakness: what we know and what we wish we did

  2013cites this paper
• Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations

  2013cites this paper
• Chapter 46 – Contraction of Muscles: Mechanochemistry

  2012cites this paper
• Detection of Differential Levels of Proteins in the Urine of Patients with Endometrial Cancer: Analysis Using Two-Dimensional Gel Electrophoresis and O-Glycan Binding Lectin

  2012cites this paper
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  2012cites this paper
• neb: a zebrafish model of nemaline myopathy due to nebulin mutation

  2011cites this paper
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  2011cites this paper
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