Impaired insulin action in subcutaneous adipocytes from women with visceral obesity.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  American Journal of Physiology. Endocrinology and Metabolism

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/AJPENDO.2001.280.1.E40PMID 11120657
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion.

  2000cited by this paper
• Insulin increases leptin mRNA expression in abdominal subcutaneous adipose tissue in humans.

  2000cited by this paper
• Surgical removal of visceral fat reverses hepatic insulin resistance.

  1999cited by this paper
• Regional postprandial fatty acid metabolism in different obesity phenotypes.

  1999cited by this paper
• Systemic resistance to the antilipolytic effect of insulin in black and white women with visceral obesity.

  1999cited by this paper
• Systemic resistance to the antilipolytic effect of insulin in black and white women with visceral obesity.

  1999cited by this paper
• Is visceral adiposity a significant correlate of subcutaneous adipose cell lipolysis in men?

  1999cited by this paper
• Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway

  1998cited by this paper
• Subcutaneous Abdominal Fat and Thigh Muscle Composition Predict Insulin Sensitivity Independently of Visceral Fat

  1997cited by this paper
• Visceral Fat and Race-Dependent Health Risks in Obese Nondiabetic Premenopausal Women

  1997influential reference
• Visceral fat in relation to health: is it a major culprit or simply an innocent bystander?

  1997cited by this paper
• Visceral fat in relation to health: is it a major culprit or simply an innocent bystander?

  1997cited by this paper
• Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM

  1997cited by this paper
• Visceral adiposity, increased adipocyte lipolysis, and metabolic dysfunction in obese postmenopausal women.

  1996cited by this paper
• Adipocyte insulin action during the normal menstrual cycle.

  1996cited by this paper
• Abdominal fat distribution and metabolic risk factors: effects of race.

  1996cited by this paper
• Regional differences in adipose tissue lipolysis from lean and obese women: existence of postreceptor alterations.

  1995cited by this paper
• Visceral adipose tissue differences in black and white women.

  1995cited by this paper
• Relationships of generalized and regional adiposity to insulin sensitivity in men.

  1995cited by this paper
• Gender differences in regional fatty acid metabolism before and after meal ingestion.

  1995cited by this paper
• Insulin resistance in adipocytes of obese women: effects of body fat distribution and race.

  1995influential reference
• Regional variation in adipose tissue metabolism of severely obese premenopausal women.

  1995cited by this paper
• Estimation of adipose tissue mass by magnetic resonance imaging: validation against dissection in human cadavers.

  1994cited by this paper
• Techniques for the measurement of visceral fat: a practical guide.

  1993cited by this paper
• Postprandial Free Fatty Acid Kinetics Are Abnormal in Upper Body Obesity

  1993cited by this paper
• Abdominal obesity as important component of insulin-resistance syndrome.

  1993cited by this paper
• Quantification of adipose tissue by MRI: relationship with anthropometric variables.

  1992cited by this paper
• Differences in skeletal muscle and bone mineral mass between black and white females and their relevance to estimates of body composition.

  1992cited by this paper
• Attenuated adenosine-sensitivity and decreased adenosine-receptor number in adipocyte plasma membranes in human obesity.

  1991cited by this paper
• Regional differences in triglyceride breakdown in human adipose tissue: effects of catecholamines, insulin, and prostaglandin E2.

  1991cited by this paper
• Effects of body fat distribution on regional lipolysis in obesity.

  1991cited by this paper
• Abdominal fat cell lipolysis, body fat distribution, and metabolic variables in premenopausal women.

  1990cited by this paper
• Increased insulin resistance and fat cell lipolysis in obese but not lean women with a high waist/hip ratio

  1990influential reference
• Microdialysis of intercellular adenosine concentration in subcutaneous tissue in humans.

  1989cited by this paper
• Influence of body fat distribution on free fatty acid metabolism in obesity.

  1989cited by this paper
• Regional adipose tissue metabolism in men and postmenopausal women.

  1987cited by this paper
• Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp.

  1987cited by this paper
• Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences

  1987cited by this paper
• In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus.

  1983cited by this paper
• Site differences in insulin receptor binding and insulin action in subcutaneous fat of obese females.

  1983cited by this paper
• Differences at the Receptor and Postreceptor Levels Between Human Omental and Subcutaneous Adipose Tissue in the Action of Insulin on Lipolysis

  1983cited by this paper
• A simple one-step enzymatic fluorometric method for the determination of glycerol in 20 microliters of plasma.

  1983cited by this paper
• Adenosine receptors in fat cells. Identification by (-)-N6-[3H]phenylisopropyladenosine binding.

  1981cited by this paper
• Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. National Diabetes Data Group.

  1979cited by this paper
• Regional differences and effect of weight reduction on human fat cell metabolism

  1979cited by this paper
• Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance

  1979cited by this paper
• A simple method to determine fat cell size and number in four mammalian species.

  1971cited by this paper
• Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells.

  1971cited by this paper
• Morphological changes in the adipocyte during fat deposition and mobilization.

  1967cited by this paper
• Coated charcoal immunoassay of insulin.

  1965cited by this paper
• A relation between non-esterified fatty acids in plasma and the metabolism of glucose.

  1956cited by this paper

• Sex-and depot-specific differences in cellular insulin responsiveness during adipose expansion.

  2025cites this paper
• Short Sleep Duration Disrupts Glucose Metabolism: Can Exercise Turn Back the Clock?

  2024cites this paper
• An Artemisia scoparia extract attenuates glucocorticoid‐induced lipolysis in adipocytes

  2023cites this paper
• Adipocyte Phenotype Flexibility and Lipid Dysregulation

  2022cites this paper
• Fat Cell Size: Measurement Methods, Pathophysiological Origins, and Relationships With Metabolic Dysregulations

  2021cites this paper
• Sex differences in white adipose tissue expansion: emerging molecular mechanisms.

  2021cites this paper
• Age and Sex: impact on adipose tissue metabolism and inflammation.

  2021cites this paper
• White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in Mice

  2021cites this paper
• The clinical impact of maternal weight on offspring health: lights and shadows in breast milk metabolome

  2021cites this paper
• The effect of macrophage polarisation on adipose tissue fibrosis in the context of hyperinsulinaemia

  2020cites this paper
• The Human Breast Milk Metabolome in Overweight and Obese Mothers

  2020cites this paper
• Impact of sex and age on metabolism, sympathetic activity, and hypertension

  2020cites this paper
• Integration of molecular profiles in a longitudinal wellness profiling cohort

  2020cites this paper
• Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

  2020cites this paper
• Exercise training-induced effects on brown and white adipose tissue metabolism in humans : positron emission tomography studies in health and insulin resistance

  2019cites this paper
• Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals

  2019cites this paper
• Sex differences in metabolism and cardiometabolic disorders

  2018cites this paper
• Body composition and cardiometabolic health: the need for novel concepts

  2018cites this paper
• PID1 alters antilipolytic action of insulin and increases lipolysis via Inhibited the activation of AKT/PKA Pathway

  2018cites this paper
• Inflammatory signatures distinguish metabolic health in African American women with obesity

  2018cites this paper
• Insulin Signalling in Human Adipocytes and its Interplay with beta-Adrenergic Control of Lipolysis

  2018cites this paper
• Cellular Mechanisms Driving Sex Differences in Adipose Tissue Biology and Body Shape in Humans and Mouse Models.

  2017cites this paper
• Gene expression regional differences in human subcutaneous adipose tissue

  2017cites this paper
• Kisspeptin-10 inhibits proliferation and regulates lipolysis and lipogenesis processes in 3T3-L1 cells and isolated rat adipocytes

  2017cites this paper
• Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome.

  2017cites this paper
• Molecular implications of adenosine in obesity.

  2017cites this paper
• Identification Of Lipolysis-Derived Lipid Mediators And The Activation Of A Pro-Inflammatory Cyclooxygenase Pathway, Via Cyclooxygenase-2, In Adipose Tissue

  2016cites this paper
• Relationships between Rodent White Adipose Fat Pads and Human White Adipose Fat Depots

  2016cites this paper
• [Overweight and obesity: review and update].

  2016cites this paper
• Obesity-related insulin resistance: implications for the surgical patient

  2015cites this paper
• Shaping fat distribution: New insights into the molecular determinants of depot‐ and sex‐dependent adipose biology

  2015cites this paper
• SUBCUTANEOUS ADIPOSE TISSUE INSULIN RESISTANCE IS ASSOCIATED WITH VISCERAL ADIPOSITY IN POSTMENOPAUSAL WOMEN

  2014cites this paper
• An Approach to Obesity as a Cardiometabolic Disease: Potential Implications for Clinical Practice

  2014cites this paper
• Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

  2014cites this paper
• Metabolic Effects of Abdominal Fats in Animal Models and Humans

  2014cites this paper
• Mechanisms by which the IKK-related Kinases Affect Energy Expenditure.

  2014cites this paper
• Interrelationships between changes in anthropometric variables and computed tomography indices of abdominal fat distribution in response to a 1-year physical activity-healthy eating lifestyle modification program in abdominally obese men.

  2014cites this paper
• Fat mass localization alters fuel oxidation during exercise in normal weight women.

  2013cites this paper
• Free Fatty Acid Flux in African American and Caucasian Adults – Effect of Sex and Race

  2013cites this paper
• Is “Sick Fat” a Cardiovascular Disease?

  2013cites this paper
• Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications.

  2013cites this paper
• Mesenchymal stem cells: A revolution in therapeutic strategies of age-related diseases

  2013cites this paper
• Low‐calorie diet induced weight loss may alter regulatory hormones and contribute to rebound visceral adiposity in obese persons with a family history of type‐2 diabetes

  2013cites this paper
• Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots.

  2013cites this paper
• Sex Differences in Obesity-Related Glucose Intolerance and Insulin Resistance

  2012cites this paper
• Adipose tissue secretion and inflammation - Characterization of novel adipokines and the impact of hypoxia on adipocyte function

  2012cites this paper
• The effects of habitual exercise and fasting on stress-evoked cytokine expression in non-obese white adipose tissue

  2012cites this paper
• A putative distinct protective fat subdepot in type 2 diabetes

  2012cites this paper
• Interrelations entre les différents indices d'adiposité et le tissu adipeux viscéral à la suite d'un programme de modification des habitudes alimentaires et d'activité physique chez des hommes dyslipidémiques avec obésité abdominale

  2012cites this paper
• Abdominal Superficial Subcutaneous Fat

  2012cites this paper
• Do novel adipokines play a causative or only modulating role in the pathogenesis of obesity and metabolic disorders?

  2012cites this paper
• Interleukin-1 beta: a potential link between stress and the development of visceral obesity

  2012cites this paper
• Sex differences in human adipose tissues – the biology of pear shape

  2012cites this paper
• Obesity and Health: Implications of Public Policy

  2012cites this paper
• Alterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity

  2011cites this paper
• Glyceroneogenesis is inhibited through HIV protease inhibitor-induced inflammation in human subcutaneous but not visceral adipose tissue

  2011cites this paper
• From PDE3B to the regulation of energy homeostasis.

  2011cites this paper
• Adiposopathy is "sick fat" a cardiovascular disease?

  2011cites this paper
• Étude de facteurs impliqués dans la variation de marqueurs inflammatoires présents dans un contexte d'obésité abdominale et de complications métaboliques associées

  2010cites this paper
• Phentermine, topiramate and their combination for the treatment of adiposopathy (‘sick fat’) and metabolic disease

  2010cites this paper
• Femoral Adipose Tissue May Accumulate the Fat That Has Been Recycled as VLDL and Nonesterified Fatty Acids

  2010cites this paper
• Anthropometric Measurements and Diabetes Mellitus: Clues to the “Pathogenic” and “Protective” Potential of Adipose Tissue

  2010cites this paper
• INVESTIGATING THE HETEROGENEITY IN REGIONAL BODY COMPOSITION, METABOLIC RISK AND RESPONSE TO WEIGHT LOSS AMONG OBESE MEN AND WOMEN

  2010cites this paper
• Gene expression profiles of diabetic mice treated with whole body hyperthermia: A high-density DNA microarray analysis

  2010cites this paper
• Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women

  2010cites this paper
• Signaling Pathways Controlling Lipolysis and Lipid Mobilization in Humans

  2010cites this paper
• Depot‐Specific Biology of Adipose Tissues: Links to Fat Distribution and Metabolic Risk

  2010cites this paper
• Associations of the limb fat to trunk fat ratio with markers of cardiometabolic risk in elderly men and women.

  2009cites this paper
• Sex differences in obesity and the regulation of energy homeostasis

  2009cites this paper
• Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity

  2008cites this paper
• Higher Post‐absorptive Skeletal Muscle LPL Activity in African American vs. Non‐Hispanic White Pre‐menopausal Women

  2008cites this paper
• Is adiposopathy (sick fat) an endocrine disease?

  2008cites this paper
• Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High‐fat Diet

  2008cites this paper
• TYPE 2 DIABETICS COMPONENTS OF THE METABOLIC SYNDROME

  2008cites this paper
• Angiotensin II: a hormone that affects lipid metabolism in adipose tissue

  2007cites this paper
• Omentin Plasma Levels and Gene Expression Are Decreased in Obesity

  2007cites this paper
• Regulation of lipolysis in adipocytes.

  2007cites this paper
• Addition of medroxyprogesterone acetate to conjugated equine estrogens results in insulin resistance in adipose tissue.

  2007cites this paper
• Independent associations of insulin resistance with high whole-body intermuscular and low leg subcutaneous adipose tissue distribution in obese HIV-infected women.

  2007cites this paper
• Body Composition and metabolic syndrome features in overweight and obese women

  2007cites this paper
• cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets for fat cell management

  2006cites this paper
• Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action.

  2006cites this paper
• An Unsuspected Metabolic Role for Atrial Natriuretic Peptides: The Control of Lipolysis, Lipid Mobilization, and Systemic Nonesterified Fatty Acids Levels in Humans

  2005cites this paper
• Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator-activated receptor- (cid:1) role

  2005cites this paper
• Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator-activated receptor-alpha.

  2005cites this paper
• Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a review

  2004cites this paper
• Exercise training increases glycogen synthase activity and GLUT4 expression but not insulin signaling in overweight nondiabetic and type 2 diabetic subjects.

  2004cites this paper
• THE EFFECTS OF OBESITY ON PLASMA LEVELS OF OMENTIN, A DEPOT-SPECIFIC ADIPOCYTOKINE

  2004cites this paper
• Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy.

  2004influential citation
• Interaction Connecting Leptin-Obesity-Insulin Dependent Diabetes Mellitus

  2004cites this paper
• Diet and nutrition in pediatric dentistry.

  2003cites this paper
• Sugars, hypertriglyceridemia, and cardiovascular disease.

  2003cites this paper
• A paradox resolved: the postprandial model of insulin resistance explains why gynoid adiposity appears to be protective.

  2003cites this paper
• Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

  2003cites this paper
• Sex steroids and insulin resistance.

  2002cites this paper
• The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations : distinct metabolic effects of two fat compartments.

  2002cites this paper
• Effect of a long-duration physical exercise on fat cell lipolytic responsiveness to adrenergic agents and insulin in obese men

  2002cites this paper